©THEBRIGHT EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
Immunology Exam 5 Questions With Verified
Answers
Which of the following molecules with cytoplasmic tails is/are associated with a BCR? -
Answers✔Igα
Igβ
In a helminth parasitic infection, which cytokine/s will lead to B-cells isotype switching to make
IgE? - Answers✔IL-4
TI antigens can activate B-cells in individuals without a thymus. - Answers✔True
How do intestinal epithelial cells help defend mucosal tissue? - Answers✔-Provide a barrier
between the gut tissue and the gut lumen
-Utilize TLR and NOD receptors to recognize bacteria
-Secrete chemokines and cytokines to recruit neutrophils and monocytes
-Secrete antimicrobial peptides
All of the above!
Which of the following is/are true about FDC's? - Answers✔-They have CR1 and CR2 on their
surface
-They have an extensive surface area
From what you learned in lecture and the power points, which cells will form a conjugate pair? -
Answers✔B-cell with T-cell
All naive B and T-cells can recirculate through the blood and enter secondary lymphoid tissues
of both the systemic and mucosal compartments. - Answers✔True
Which of the following is/are occurring in the germinal centers? - Answers✔Proliferation
Somatic Hypermuation
1
, ©THEBRIGHT EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
Isotype switching
Antigen binding selection
Correct! All of the above
Mucins _______. - Answers✔thicken mucus
Expression of Bcl-xL by a centroblast in the dark zone prevents it from dying by apoptosis. -
Answers✔False
The process by which an antibody increases its affinity for a specific antigen during an immune
response is: - Answers✔Affinity Maturation
Which of the following is/are characteristic of intestinal macrophages? - Answers✔Phagocytosis
The Fc portion of IgE is bound by ______ which is found on _________. - Answers✔FcεRI;
mast cells
Tingible body macrophage is the terminology used to refer to macrophages that have recently
engulfed apoptotic centrocytes in the germinal centers. - Answers✔True
What is true about individuals that suffer from hyper-IgM syndrome? - Answers✔-They lack the
CD40 ligand
-Their B cells can't undergo isotype switching
Centrocytes activated in the presence of IL-10 will differentiate into plasma cells, while those
that interact with IL-4 will differentiate into memory B-cells. - Answers✔True
Which of the following chemokines is/are responsible for attracting B-cells into the B-cell
follicle? - Answers✔CXCL13
Which lymphocyte is involved in fighting parasitic infections and has orangish-red granules in
it's cytoplasm? - Answers✔Eosinophils
Mast cells
Basophils
Macrophages
Correct Answer: None of the above
Which of the following transports IgG across the placenta to the fetus? - Answers✔-FcRn
-FcRB
-Brambell receptor
2
ALL RIGHTS RESERVED.
Immunology Exam 5 Questions With Verified
Answers
Which of the following molecules with cytoplasmic tails is/are associated with a BCR? -
Answers✔Igα
Igβ
In a helminth parasitic infection, which cytokine/s will lead to B-cells isotype switching to make
IgE? - Answers✔IL-4
TI antigens can activate B-cells in individuals without a thymus. - Answers✔True
How do intestinal epithelial cells help defend mucosal tissue? - Answers✔-Provide a barrier
between the gut tissue and the gut lumen
-Utilize TLR and NOD receptors to recognize bacteria
-Secrete chemokines and cytokines to recruit neutrophils and monocytes
-Secrete antimicrobial peptides
All of the above!
Which of the following is/are true about FDC's? - Answers✔-They have CR1 and CR2 on their
surface
-They have an extensive surface area
From what you learned in lecture and the power points, which cells will form a conjugate pair? -
Answers✔B-cell with T-cell
All naive B and T-cells can recirculate through the blood and enter secondary lymphoid tissues
of both the systemic and mucosal compartments. - Answers✔True
Which of the following is/are occurring in the germinal centers? - Answers✔Proliferation
Somatic Hypermuation
1
, ©THEBRIGHT EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
Isotype switching
Antigen binding selection
Correct! All of the above
Mucins _______. - Answers✔thicken mucus
Expression of Bcl-xL by a centroblast in the dark zone prevents it from dying by apoptosis. -
Answers✔False
The process by which an antibody increases its affinity for a specific antigen during an immune
response is: - Answers✔Affinity Maturation
Which of the following is/are characteristic of intestinal macrophages? - Answers✔Phagocytosis
The Fc portion of IgE is bound by ______ which is found on _________. - Answers✔FcεRI;
mast cells
Tingible body macrophage is the terminology used to refer to macrophages that have recently
engulfed apoptotic centrocytes in the germinal centers. - Answers✔True
What is true about individuals that suffer from hyper-IgM syndrome? - Answers✔-They lack the
CD40 ligand
-Their B cells can't undergo isotype switching
Centrocytes activated in the presence of IL-10 will differentiate into plasma cells, while those
that interact with IL-4 will differentiate into memory B-cells. - Answers✔True
Which of the following chemokines is/are responsible for attracting B-cells into the B-cell
follicle? - Answers✔CXCL13
Which lymphocyte is involved in fighting parasitic infections and has orangish-red granules in
it's cytoplasm? - Answers✔Eosinophils
Mast cells
Basophils
Macrophages
Correct Answer: None of the above
Which of the following transports IgG across the placenta to the fetus? - Answers✔-FcRn
-FcRB
-Brambell receptor
2
