Neurotransmitters
Compiled By Simon Mwangi
Edition: 2024/25
, Science | Biochemistry I of VI pages
1. electrical synapses
two neurons connected by a gap junction, which allows electrical current to flow directly from one cell to the
2. what do chemical synapses release?
NT from the presynaptic membrane which bind t receptors of the postsynaptic membrane
3. chemical synapses specify..
which will happen to a neuron, can regulate depending on what ligands and receptors are present
4. NT trigger (2) or modulate the postsynaptic cell
EPSPs/IPSPs
5. quanta
amount of NT located within
6. where are SNAREs located (2)
vesicle membrane
presynaptic membrane
7. SNARE proteins I the SV and plasma membrane help to
dock the vesicles and then zip together t oforce the membranes to fuse
8. triggers fusion and exocytosis
calcium
9. botulinum toxin
cleaves SNARES so the vesicle cant fuse with the membrane which prevents release of acetylcholine and
10. botulinum toxin involves (2)
SNAP 25
syntaxin
11. depending on the NT and the type of receptor it binds to, it can either
excite or inhibit the postsynaptic membrane
12. excitatory NT (3)
glutamateaspartame nitric oxide
13. inhibitory NT (4)
glycineGABAserotonindopamine
14. both excitatory and inhibitory NT (2)
acetylcholine
norepinephrine
15. resting MP
-65 mV
Biochemistry 2024/25 Edition