NSG 533 Advanced Pharmacology Test 1
Week 4 Exam Questions and Answers
100% Pass
Which of the following SSRIs requires up to a 5-week washout period
because of the
long half-life of its potent active metabolite?
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine
D. Sertraline - ✔✔C
Which of the following symptoms is most likely to improve within
approximately 1 week
of starting treatment?
A. Depressed mood
B. Suicidal thoughts
C. Anhedonia
D. Sleep - ✔✔D
1
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,Of the following combinations of medications, which one would you want to
avoid?
A. Fluoxetine-lithium
B. Fluoxetine-phenelzine
C. Citalopram-valproic acid
D. Citalopram-aripiprazole - ✔✔B
A 26-year-old man with a history of depression has been taking sertraline
200 mg/day for 12 weeks with no response. The patient has no other
complications. The physician asks for your recommendation. The most
reasonable recommendation would be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine
E. Decrease sertraline - ✔✔D
Which of the following is a dangerous combination?
A. MAOI-lorazepam
B. MAOI-acetaminophen
C. MAOI-meperidine
D. MAOI-ziprasidone - ✔✔C
2
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
, A 23-year-old married white woman comes to the outpatient psychiatric
clinic
complaining of decreased sleep, decreased appetite, decreased
concentration, depressed
mood, thoughts of death, and lack of interest in activities for 6 weeks'
duration. She has
no history of psychiatric illness and takes no medications except for Ortho-
Tri Cyclen Lo
daily. Based upon the patients symptoms, choose the best medication to
treat this patient.
A. Nefazodone 100 mg po twice daily
B. Paroxetine 20 mg po daily
C. St. John's wort 300 mg po three times daily
D. Amitriptyline 25 mg at bedtime - ✔✔B
A 36-year-old man is admitted to the hospital for a severe methicillin-
resistant Staphylococcus aureus diabetic foot infection and is started on
linezolid 600 mg IV every 12 hours. His medication profile includes
paroxetine 40 mg every morning, trazodone 100 mg at bedtime as needed
for sleep, and metformin 1000 mg po twice daily. After 3
3
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
Week 4 Exam Questions and Answers
100% Pass
Which of the following SSRIs requires up to a 5-week washout period
because of the
long half-life of its potent active metabolite?
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine
D. Sertraline - ✔✔C
Which of the following symptoms is most likely to improve within
approximately 1 week
of starting treatment?
A. Depressed mood
B. Suicidal thoughts
C. Anhedonia
D. Sleep - ✔✔D
1
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
,Of the following combinations of medications, which one would you want to
avoid?
A. Fluoxetine-lithium
B. Fluoxetine-phenelzine
C. Citalopram-valproic acid
D. Citalopram-aripiprazole - ✔✔B
A 26-year-old man with a history of depression has been taking sertraline
200 mg/day for 12 weeks with no response. The patient has no other
complications. The physician asks for your recommendation. The most
reasonable recommendation would be to:
A. Increase sertraline
B. Add fluoxetine
C. Switch to amitriptyline
D. Change to venlafaxine
E. Decrease sertraline - ✔✔D
Which of the following is a dangerous combination?
A. MAOI-lorazepam
B. MAOI-acetaminophen
C. MAOI-meperidine
D. MAOI-ziprasidone - ✔✔C
2
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
, A 23-year-old married white woman comes to the outpatient psychiatric
clinic
complaining of decreased sleep, decreased appetite, decreased
concentration, depressed
mood, thoughts of death, and lack of interest in activities for 6 weeks'
duration. She has
no history of psychiatric illness and takes no medications except for Ortho-
Tri Cyclen Lo
daily. Based upon the patients symptoms, choose the best medication to
treat this patient.
A. Nefazodone 100 mg po twice daily
B. Paroxetine 20 mg po daily
C. St. John's wort 300 mg po three times daily
D. Amitriptyline 25 mg at bedtime - ✔✔B
A 36-year-old man is admitted to the hospital for a severe methicillin-
resistant Staphylococcus aureus diabetic foot infection and is started on
linezolid 600 mg IV every 12 hours. His medication profile includes
paroxetine 40 mg every morning, trazodone 100 mg at bedtime as needed
for sleep, and metformin 1000 mg po twice daily. After 3
3
©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.
