PCB 4522: MOLECULAR GENETICS PRACTICE EXAM 3
WITH ACCURATE & VERIFIED QUESTIONS 100%
SOLVED
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. The -chain locus is positioned within the -chain locus, and is consequently deleted and inactivated during
rearrangement of the gene segments.
a. True b. False
2. Gene rearrangements of the light chain include all of the following, except:
a. At least four possible attempts for a successful rearrangement.
b. Rearrangement of the genes first, and then the genes.
c. If no successful rearrangements are made, apoptosis will result.
d. Rearrangement of the genes first, and then the genes.
3. T-cell receptors will typically bind antigen using multipoint attachment, which is achieved using two
, opposing human cell surfaces.
a. True b. False
4. Which of the following cell types does NOT express MHC class I?
a. Erythrocytes d. Dendritic cells
b. Hepatocytes e. Macrophages
c. Lymphocytes
5. T-cell receptor diversity is established by:
a. somatic hypermutation in the secondary lymphoid tissues
b. somatic recombination in the thymus
c. somatic hypermutation in the thymus
d. somatic recombination in the secondary lymphoid tissues
6. Although T cells differ from B cells in that they require MHC molecules for antigen processing, both T cells
and B cells will always bind soluble antigens.
a. True b. False
7. Which of the following components are included in the CD3 complex?
a. CD3 d. Ig and Ig
b. CD3 e. All of the above
c. CD3
8. During the maturation of both B cells and T cells, which of the following enzymes would you expect to be
working?
a. RAG-1 & RAG-2 d. A & B
b. AID e. A & C
c. TdT
WITH ACCURATE & VERIFIED QUESTIONS 100%
SOLVED
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. The -chain locus is positioned within the -chain locus, and is consequently deleted and inactivated during
rearrangement of the gene segments.
a. True b. False
2. Gene rearrangements of the light chain include all of the following, except:
a. At least four possible attempts for a successful rearrangement.
b. Rearrangement of the genes first, and then the genes.
c. If no successful rearrangements are made, apoptosis will result.
d. Rearrangement of the genes first, and then the genes.
3. T-cell receptors will typically bind antigen using multipoint attachment, which is achieved using two
, opposing human cell surfaces.
a. True b. False
4. Which of the following cell types does NOT express MHC class I?
a. Erythrocytes d. Dendritic cells
b. Hepatocytes e. Macrophages
c. Lymphocytes
5. T-cell receptor diversity is established by:
a. somatic hypermutation in the secondary lymphoid tissues
b. somatic recombination in the thymus
c. somatic hypermutation in the thymus
d. somatic recombination in the secondary lymphoid tissues
6. Although T cells differ from B cells in that they require MHC molecules for antigen processing, both T cells
and B cells will always bind soluble antigens.
a. True b. False
7. Which of the following components are included in the CD3 complex?
a. CD3 d. Ig and Ig
b. CD3 e. All of the above
c. CD3
8. During the maturation of both B cells and T cells, which of the following enzymes would you expect to be
working?
a. RAG-1 & RAG-2 d. A & B
b. AID e. A & C
c. TdT
