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PHRM30002 – Glia Exam Questions With
Correct Answers
Microglia are immune cells, Astrocytes affect synapses and cover endothelium,
Oligodendrocytes wrap neurons to form myelin sheath - answer✔What are three major types
of glia and what do they do?
Directly modulate neuronal function - answer✔Not only can the glia support neurons, what else
do they do?
Damage may lead to demyelination, affecting ap propogation and thus CNS function -
answer✔How can oligodendrocytes be so core to CNS function?
Can alter phenotype to change release of chemo/cytokines, there are multitude of pro and anti
inflammatory phentypes - answer✔What do microglia often do in response to stimuli? What
complicates the targetting of this?
Synaptic pruning by phagocytosis of neurons, can be excessively done in disease -
answer✔What is the main process of microglia? What often goes wrong with this in disease?
Can release pro-inflammatory cytokines - answer✔Like microglia, how can astrocytes promote
inflammation?
1|Page
ALL RIGHTS RESERVED.
PHRM30002 – Glia Exam Questions With
Correct Answers
Microglia are immune cells, Astrocytes affect synapses and cover endothelium,
Oligodendrocytes wrap neurons to form myelin sheath - answer✔What are three major types
of glia and what do they do?
Directly modulate neuronal function - answer✔Not only can the glia support neurons, what else
do they do?
Damage may lead to demyelination, affecting ap propogation and thus CNS function -
answer✔How can oligodendrocytes be so core to CNS function?
Can alter phenotype to change release of chemo/cytokines, there are multitude of pro and anti
inflammatory phentypes - answer✔What do microglia often do in response to stimuli? What
complicates the targetting of this?
Synaptic pruning by phagocytosis of neurons, can be excessively done in disease -
answer✔What is the main process of microglia? What often goes wrong with this in disease?
Can release pro-inflammatory cytokines - answer✔Like microglia, how can astrocytes promote
inflammation?
1|Page
