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What is the most common skin condition in the U.S.? - ✔✔acne vulgaris
What type of acne often flares prior to menses? - ✔✔female hormonal acne
What 4 main factors contribute to acne? - ✔✔excessive sebum production
abnormal keratonization of follicles
colonization of P acne
inflammation of the follicle and surrounding tissue
What is important to assess in women c/o acne? - ✔✔menstrual and contraception hx
What is important to assess in med presenting with c/o acne? - ✔✔med hx such as corticosteroids or
testosterone replacement
Treatment for mild comedonal acne? - ✔✔topical retinoid for 6-12 weeks
less than 15 inflammatory acne lesions indicate what severity? more than 15? - ✔✔mild-mod; severe
What is a common inflammatory disorder that may present with papules, pustules, telangiectasias (ie,
spider veins), or erythema involving the central face. Tends to manifest at a later age than acne, and the
lack of comedones (the primary lesion of acne) is a distinguishing feature. The papular component favors
the malar region, chin, and forehead. The presence of telangiectasias and a history of easy flushing can
also aid in establishing the correct diagnosis. - ✔✔Rosacea
What should patients be warned about when taking topical steroids for acne? - ✔✔may cause a mild acne
flare before providing improvement
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,What is the main side effect of topical retinoids? - ✔✔irritation
Which retinoid is regarded as the most effective, but also causes the most irritation? - ✔✔Tazarotene
What acne tx works by reducing P acnes numbers, suppressing the growth of these bacteria, and killing
them without inducing bacterial resistance? - ✔✔benzoyl peroxide
What is the main adverse effect of benzoyl peroxide? - ✔✔irritant contact dermatitis
What education should be provided with benzoyl peroxide? - ✔✔should be aware that benzoyl peroxide
can bleach clothing, towels, bed linens, and even hair
Also considered safe and effective, these commonly prescribed agents improve acne by acting directly on
P acnes colonization and inhibiting the proinflammatory effects of these bacteria on comedogenesis -
✔✔topical abx
What are 2 commonly used topical abx? - ✔✔clindamycin and erythromycin
What is a preferable choice in the tx of acne because it has proven efficacy and tolerability and prevents
the development of antimicrobial resistance? - ✔✔a combination of clindamycin and benzoyl peroxide
(eg, Duac)
What is the preferred prescribed oral abx for the tx of acne? What about in pregnant pts? -
✔✔tetracycline/ doxy; erythromycin
All tetracyclines should be avoided in children younger than _____ years because they can stain growing
teeth - ✔✔11
How long does improvement of acne usually take with tx? - ✔✔3 months
What are the primary agents used to treat postadolescent acne? - ✔✔Flutamine and spironolactone
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, What is the moa of flutamine and spironolactone in the tx of acne? - ✔✔block the effects of androgen on
sebacous glands
What should be monitored in any patient on flutamine? - ✔✔LFTs
When flutamine or spironolactone is used in women, what should it be used in combination with? -
✔✔OCPs
What areas of the body should strong steroids be avoided? - ✔✔face, flexers, and scrotum
What is Rosacea and what is it characterized by? - ✔✔a chronic inflammatory disorder characterized by
centrofacial erythema, flushing, papules, pustules, and
telangiectasias
How is acne and rosacea differentiated? - ✔✔Rosacea does not have open and closed comedones and
generally more centrally located
What triggers rosacea? - ✔✔alcohol, hot food or drink, spicy food, sunlight, temperature extremes, stress,
exercise, hot baths, topical corticosteroids, and vasodilatory medications
What 2 topical agents are used to tx rosacea? - ✔✔metronidazole and topical azelaic acid,
What is first line therapy for hyperpigmentation? - ✔✔hydroquinone
What is a common pigment disorder more common in black, Hispanic and Asian individuals, and has
been
linked to hormonal and genetic factors, as well as exposure to UV radiation. It is characterized by
irregular light brown to gray-brown patches more often on the face, including the cheeks, nose and
forehead regions, but also seen on the chest and arms - ✔✔Melasma
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