NURS 5334 Antimicrobial Recall Quiz: Questions And
Answers (Score A+)
At what age are adult levels of renal function achieved Right Ans - 12
months
What is the most accurate device for measuring a 2.5mL dose for a child
Right Ans - An oral syringe
How do you help prevent medication errors Right Ans - Write out the term
daily
In pediatric patients gastric acidity does not reach adult values for Right
Ans - 2 years
Why do many medications lack pediatric dosing information in their drug
labeling Right Ans - There is lack of evidence-based literature on the safe
and effective use of medications in children
Why are neonates at greater risk for toxicity with highly protein-bound drugs
Right Ans - Protein binding is decreased in neonates increasing the amount of
free drug available
Nalidixic acid may cause _______ in children Right Ans - cartilage erosion
Altered absorption of drugs in the elderly may result in _______ drug response
Right Ans - Delayed
You have an elderly patient taking warfarin. You add another protein binding
drug. Which of the following statements is correct? Right Ans - You will
need to decrease dose of warfarin
In elderly, proper index of renal function is _____ Right Ans - Glomerular
filtration rate (GFR)
List that identifies drugs with high likelihood of cause adverse effects in
elderly Right Ans - Beers list
, Primary mechanism of antibacterial action of the penicillin's involve
inhibition of Right Ans - Cell wall synthesis by binding and inactivating
penicillin binding proteins (PBPs)
Which statement about vancomycin is accurate Right Ans - Increases
bacterial cell wall permeability and inhibits RNA synthesis
The mechanism of action of the tetracyclines involves Right Ans - Inhibiting
protein synthesis
Mechanism of action of aminoglycosides Right Ans - Causes misreading of
the code on the mRNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin
Right Ans - Gentamicin continues to exert antibacterial effects even after
plasma level decrease below detectable levels
If a patient was treated with the macrolide erythromycin, he/she should
Right Ans - Temporarily stop simvastatin while taking erythromycin
24 year old woman returned from vacation abroad suffering from traveler's
diarrhea, and her problem has not responded to antidiarrheal drugs. A
pathogenic gram-negative bacillus is suspected. Which drug is most likely to
be effective in the treatment of this patient Right Ans - Ciprofloxacin
Which is accurate about fluoroquinolones Right Ans - Fluoroquinolones
have different therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides Right
Ans - Skin reactions
Which is true about ciprofloxacin Right Ans - During treatment, tendonitis
and even tendon rupture may occur
Primary reason for the use of drug combinations in treatment of TB is to
Right Ans - Delay or prevent emergence of resistance
Which is true about fluconazole Right Ans - Primary route of excretion is
renal
Answers (Score A+)
At what age are adult levels of renal function achieved Right Ans - 12
months
What is the most accurate device for measuring a 2.5mL dose for a child
Right Ans - An oral syringe
How do you help prevent medication errors Right Ans - Write out the term
daily
In pediatric patients gastric acidity does not reach adult values for Right
Ans - 2 years
Why do many medications lack pediatric dosing information in their drug
labeling Right Ans - There is lack of evidence-based literature on the safe
and effective use of medications in children
Why are neonates at greater risk for toxicity with highly protein-bound drugs
Right Ans - Protein binding is decreased in neonates increasing the amount of
free drug available
Nalidixic acid may cause _______ in children Right Ans - cartilage erosion
Altered absorption of drugs in the elderly may result in _______ drug response
Right Ans - Delayed
You have an elderly patient taking warfarin. You add another protein binding
drug. Which of the following statements is correct? Right Ans - You will
need to decrease dose of warfarin
In elderly, proper index of renal function is _____ Right Ans - Glomerular
filtration rate (GFR)
List that identifies drugs with high likelihood of cause adverse effects in
elderly Right Ans - Beers list
, Primary mechanism of antibacterial action of the penicillin's involve
inhibition of Right Ans - Cell wall synthesis by binding and inactivating
penicillin binding proteins (PBPs)
Which statement about vancomycin is accurate Right Ans - Increases
bacterial cell wall permeability and inhibits RNA synthesis
The mechanism of action of the tetracyclines involves Right Ans - Inhibiting
protein synthesis
Mechanism of action of aminoglycosides Right Ans - Causes misreading of
the code on the mRNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin
Right Ans - Gentamicin continues to exert antibacterial effects even after
plasma level decrease below detectable levels
If a patient was treated with the macrolide erythromycin, he/she should
Right Ans - Temporarily stop simvastatin while taking erythromycin
24 year old woman returned from vacation abroad suffering from traveler's
diarrhea, and her problem has not responded to antidiarrheal drugs. A
pathogenic gram-negative bacillus is suspected. Which drug is most likely to
be effective in the treatment of this patient Right Ans - Ciprofloxacin
Which is accurate about fluoroquinolones Right Ans - Fluoroquinolones
have different therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides Right
Ans - Skin reactions
Which is true about ciprofloxacin Right Ans - During treatment, tendonitis
and even tendon rupture may occur
Primary reason for the use of drug combinations in treatment of TB is to
Right Ans - Delay or prevent emergence of resistance
Which is true about fluconazole Right Ans - Primary route of excretion is
renal
