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UMN BIOC 3021 Exam 2 Questions And
Answers (Guaranteed A+)
Proteins that can be classified according to the type and arrangement of secondary structure -
answer✔(a) Antiparallel α-helix proteins
(b) Parallel or mixed β-sheet proteins
(c) Antiparallel β-sheet proteins
(d) Metal- and disulfide-rich proteins
Protein Domains or Modules - answer✔amino acid sequences
that are used repeatedly in the same protein or that are
found in different proteins
How many proteins domains? - answer✔40-100
Step 1 of Protein Folding - answer✔A newly synthesized polypeptide first forms segments
of secondary structure (α-helix and β-sheet)
step 2 of protein folding - answer✔These coalesce into a globular structure, primarily
through hydrophobic interactions
Step 3 of protein folding - answer✔The final stable tertiary structure is generated by small
adjustments to the folded structure
Step 4 of protein folding - answer✔In the cell, protein folding may require the assistance of
molecular chaperones
quaternary Structure - answer✔refers to the association of protein subunits to
form multi-subunit complexes
Monolayers and Micelles - answer✔produced by amphipathic lipid molecules
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interacting with water
Micelles - answer✔lipid aggregates which have the hydrophobic tails in the
center and polar head groups facing outward
Bilayers - answer✔produced spontaneously by certain lipids, particularly
phospholipids, instead of micelles
Bilayers - answer✔Normally wrap around themselves to form closed vesicles, which
can consist of multiple bilayers.
Liposomes - answer✔Vesicles with a single lipid bilayer
Liposomes - answer✔Can be used as drug or enzyme delivery systems in
therapeutic applications.
the phospholipid bilayer - answer✔fluid supporting matrix for
membrane proteins, and both lipids and proteins are capable of
lateral and transverse movement.
Peripheral membrane proteins - answer✔external to the lipid bilayer
Integral membrane proteins - answer✔extend into or through the lipid bilayer
Lipid-Anchored Membrane Proteins - answer✔Membrane proteins are covalently linked to lipid
molecules.
Peptidoglycan - answer✔the strong, protective peptide/
polysaccharide layer of bacterial cell walls
Gram-negative bacteria - answer✔have the peptidoglycan layer
between two lipid bilayers
Gram-positive bacteria - answer✔have a thicker peptidoglycan layer external to a
single lipid bilayer.
Glycoproteins - answer✔on the cell surface
Proteoglycans - answer✔in the extracellular matrix
Glycoproteins - answer✔Proteins with covalently-linked oligo- or
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