Chemotherapy and Biotherapy Guidelines - ONS 942p Exam Questions and Answers

Chemotherapy and Biotherapy Guidelines - ONS 942p Exam Questions and Answers nadir - lowest blood cell count after chemotherapy, 10-14 days but varies with individual agents cisplatin - ototoxic --> report tinnitus nephrotoxic --> monitor BUN and creatinine depletes K and Mg --> replacement prior/after cytoxan - hemorrhagic cystitis >3000ml/day fluid intake unless contraindicated void q2-4 hours day, q4 hours night can also cause sinus drainage, slow infusion oxaliplatin - hang with D5W cold sensitivity (Ixnay on the ice, okay?) Copyright ©EMILLECT 2024. ALL RIGHTS RESERVED. Page 2/11 irinotecan - diarrhea (I run to the can) nephrotoxic - avastin - protein in urine cisplatin zometa hypersensitivity reactions - taxol rituxan and other MAbs herceptin zometa - know creatinine prior run over at least 15 mins osteonecrosis of jaw taxol - titrate first couple doses peripheral neuropathy cryotherapy need filtered line Copyright ©EMILLECT 2024. ALL RIGHTS RESERVED. Page 3/11 (Are YEW going to react?) avastin - MAb - angiogenesis inhibitor colorectal, kidney, cervical, NSCLC, brain HTN, proteinuria can affect healing; hold 4 weeks prior to/after surgery cardiotoxic - adriamycin/doxorubi