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Biochemistry 301 Exam 3 and Answers
What is the function of the citric acid cycle? - Answers✓✓Harvest high energy electrons from
carbon fuels
What product is found by the condensation of oxaloacetate and acetyl CoA? -
Answers✓✓Citrate
What makes up citrate? - Answers✓✓- Acetyl CoA
- Oxaloacetate
What is the intermediate between citrate and isocitrate? - Answers✓✓Cis-aconitate
Where is succinate dehydrogenase located? - Answers✓✓Inner membrane of mitochondria
What intermediate in the citric acid cycle is at both the beginning and end of the cycle? -
Answers✓✓Oxaloacetate
What is the product of the complete oxidation of carbon in the citric acid cycle? -
Answers✓✓Carbon Dioxide
What name is suggested for associated multienzyme complexes in metabolism? -
Answers✓✓Metabolon
What substance is a competitive inhibitor of succinate dehydrogenase? - Answers✓✓Melonate
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What is the primary control point of the citric acid cycle? - Answers✓✓Isocitrate
dehydrogenase
What is the name applied to metabolic reactions that replenish the citric acid cycle
intermediates that are depleted because they were used for biosynthesis? -
Answers✓✓Anaplerotic reactions
What form are the carbons from carbohydrates in when they enter the citric acid cycle? -
Answers✓✓Acetyl CoA
What is produced by a substrate-level phosphorylation in the citric cycle? - Answers✓✓GTP
What state is the free energy at the standard state for MDH in the direction of the citric acid in?
- Answers✓✓Positive
What type of reactions fill up a cycle with outside carbon compounds? -
Answers✓✓Anaplerotic reactions
What enzyme in the citric acid cycle is also an example of an iron-sulfur protein? -
Answers✓✓Aconitase or succinate dehydrogenase
What organelles in plants and some bacteria where two-carbon acetyl units are converted into
four-carbon units (succinate) for glucose synthesis. energy production. and biosynthesis? -
Answers✓✓Glyoxysomes
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Which intermediate in the oxidation of isocitrate is decarboxylated to form alpha-ketoglutarate?
- Answers✓✓Oxalosuccinate
What energy conditions (high or low) is the citric acid cycle inhibited by? - Answers✓✓High
What is the first intermediate to be oxidized in the citric acid cycle? - Answers✓✓Isocitrate
What cycle are organisms that can convert fat into sugar use? - Answers✓✓Glyoxylate cycle
What would a mutation in the active site of a succinyl CoA synthetase where His is converted
to a lysine would result in? - Answers✓✓The loss of a succinyl phosphate intermediate
What molecule initiates the citric acid cycle by reacting with oxaloacetate? -
Answers✓✓Acetyl CoA
What enzyme in muscle is used to catalyze a substrate-level phosphorylation? -
Answers✓✓Succinyl CoA synthetase
Where does the direct channeling of proteins from one enzyme to the next happen? -
Answers✓✓Metabolon
What vitamins are precursors to coenzymes that are necessary for the formation of succinyl
CoA from alpha-ketoglutarate? - Answers✓✓- Thiamine
- Riboflavin
- Niacin
- Lipoic acid