NURS 180 Quiz 6 QUESTIONS AND ANSWERS
WITH VERIFIED SOLUTIONS 100% CORRECT
Biological Response Modifiers (BRMs) - ANSWER Proteins naturally produced
by the immune system and enhanced body's immune system.
FUNCTIONS:
-enhances immune system's ability to kill abnormal cells
-change cancer cells to wct like healthy cells
Signs and symptoms of hypersensitivity with antibiotics - ANSWER
colony stimulating factors - ANSWER Proteins that regulate growth,
maturation, and differentiation of bone marrow stem cells
USE: cancer treatment and neutropenia
ACTION:
-promote growth of blood cells
-decrease the length of post treatment neutropenia
-permit the delivery of higher doses of chemotherapy
-reduce bone marrow recovery time after bone marrow transplantation
-CSF therapy shortens the length of time patients are susceptible to life-
threatening infections due to low numbers of neutrophils
,-increase the production of new leukocytes
INDICATIONS:
-undergoing chemotherapy
-receiving bone marrow of stem cell transplants
-having certain malignancies
Hematopoietic Growth Factors (HGFs) - ANSWER The cytokines influencing the
proliferation and differentiation of blood cell precursors
-DARBEPOETIN AND ERYTHROPOIETIN EPOETIN ALFA
ADVERSE EFFECTS:
-hypertension
-seizures
-heart failure
-MI
-Stroke
Erythropoietin - ANSWER A hormone produced and released by the kidney
that stimulates the production of red blood cells by the bone marrow.
-Epoetin Alfa
epoetin alfa (Epogen, Procrit) - ANSWER biosynthetic form of erythropoietin
ACTION:
,-Chronic Renal Failure: cannot secrete enough endogenous erythropoietin
-Undergoing cancer chemotherapy: counteract the anemia caused by
antineoplastic drugs
-Prior to blood transfusion
ADMIN:
-SubQ route 3x/week until a therapeutic response
-Do not shake vial but gently rotate
-refrigerate vials
-one time use vials (remaining should be trashed
SIDE EFFECTS:
-anaphylaxis
-hypertension (30% of pts; asses BP and concurrent with antihypertensive drugs)
-flu like symptoms
-red cell aplasia
-edema
-bronchospasm
LAB ASSESSMENT:
HBG: Men-14-18 Women-12-16
HCT: Men-40-54 Women-36-48
OUTCOME:
-increase HGB/HCT
, -Less SOB
-Increase Energy
Ferrous Sulfate - ANSWER Iron supplement containing 20-30 percent
prevent iron deficit anemia
ADMIN:
-when administering IV be careful to prevent infiltration because iron is highly
irritating to tissues
-use Z track method when giving IM
-do not crush or empty
-do not give tablets within 1 hr of bedtime
-pregnancy category A
ADVERSE EFFECTS:
-darken stool (harmless)
-constipation (increase fiber and fluids)
-do not take with antacids
-take with food but decrease absorption
-ideally administer 1 hr before or 2 hrs after
Filgrastim (Neupogen) - ANSWER colony stimulating factor
ACTIONS:
-increase white blood well production in the bone marrow
-enhance phagocytes and cytotoxic functions of existing neutrophils
WITH VERIFIED SOLUTIONS 100% CORRECT
Biological Response Modifiers (BRMs) - ANSWER Proteins naturally produced
by the immune system and enhanced body's immune system.
FUNCTIONS:
-enhances immune system's ability to kill abnormal cells
-change cancer cells to wct like healthy cells
Signs and symptoms of hypersensitivity with antibiotics - ANSWER
colony stimulating factors - ANSWER Proteins that regulate growth,
maturation, and differentiation of bone marrow stem cells
USE: cancer treatment and neutropenia
ACTION:
-promote growth of blood cells
-decrease the length of post treatment neutropenia
-permit the delivery of higher doses of chemotherapy
-reduce bone marrow recovery time after bone marrow transplantation
-CSF therapy shortens the length of time patients are susceptible to life-
threatening infections due to low numbers of neutrophils
,-increase the production of new leukocytes
INDICATIONS:
-undergoing chemotherapy
-receiving bone marrow of stem cell transplants
-having certain malignancies
Hematopoietic Growth Factors (HGFs) - ANSWER The cytokines influencing the
proliferation and differentiation of blood cell precursors
-DARBEPOETIN AND ERYTHROPOIETIN EPOETIN ALFA
ADVERSE EFFECTS:
-hypertension
-seizures
-heart failure
-MI
-Stroke
Erythropoietin - ANSWER A hormone produced and released by the kidney
that stimulates the production of red blood cells by the bone marrow.
-Epoetin Alfa
epoetin alfa (Epogen, Procrit) - ANSWER biosynthetic form of erythropoietin
ACTION:
,-Chronic Renal Failure: cannot secrete enough endogenous erythropoietin
-Undergoing cancer chemotherapy: counteract the anemia caused by
antineoplastic drugs
-Prior to blood transfusion
ADMIN:
-SubQ route 3x/week until a therapeutic response
-Do not shake vial but gently rotate
-refrigerate vials
-one time use vials (remaining should be trashed
SIDE EFFECTS:
-anaphylaxis
-hypertension (30% of pts; asses BP and concurrent with antihypertensive drugs)
-flu like symptoms
-red cell aplasia
-edema
-bronchospasm
LAB ASSESSMENT:
HBG: Men-14-18 Women-12-16
HCT: Men-40-54 Women-36-48
OUTCOME:
-increase HGB/HCT
, -Less SOB
-Increase Energy
Ferrous Sulfate - ANSWER Iron supplement containing 20-30 percent
prevent iron deficit anemia
ADMIN:
-when administering IV be careful to prevent infiltration because iron is highly
irritating to tissues
-use Z track method when giving IM
-do not crush or empty
-do not give tablets within 1 hr of bedtime
-pregnancy category A
ADVERSE EFFECTS:
-darken stool (harmless)
-constipation (increase fiber and fluids)
-do not take with antacids
-take with food but decrease absorption
-ideally administer 1 hr before or 2 hrs after
Filgrastim (Neupogen) - ANSWER colony stimulating factor
ACTIONS:
-increase white blood well production in the bone marrow
-enhance phagocytes and cytotoxic functions of existing neutrophils
