LUPUS (SYSTEMIC LUPUS
ERYTHEMATOSUS (SLE)) (LPN)
QUESTIONS WITH COMPLETE
ANSWERS
The bbnurse bbis bbpreparing bba bbpresentation bbon bbsystemic bblupus bberythematosus
bb(SLE). bbwhich bbstatement bbshould bbthe bbnurse bbinclude? bbSATA
A) bbThe bbetiology bbis bbknown bbto bbbe bblinked bbto bbenvironmental bbfactors
B) bbSLE bbis bba bbresult bbof bbdeposition bbof bbantigen-antibody bbcomplexes bbin
bbconnective bbtissues
C) bbThe bbimmune bbcomplex bbdeposits bbtrigger bban bbinflammatory bbresponse
D) bbThe bbinflammatory bbresponse bbleads bbto bbanaphylactic bbshock
E) bbManifestations bbcan bbbe bbmild bbto bbfatal, bbwith bbremissions bband bbexacerbations
bb- bbAnswer bbB, bbC, bbE
Rationale: bb
The bbpathophysiology bbof bbsystemic bblupus bberythematosus bbis bba bbresult bbof bbthe
bbformation bbof bb
antigen-antibody
immunocomplexes bbthat bbare bbdeposited bbin bbthe bbconnective bbtissue bband bbtrigger
bban bbinflammatory bbresponse. bbThe bbmanifestations bbof bbthe bbdisease bbcan bbbe
bbmild bbto bbfatal, bband bbremissions bbare bbfollowed bbby bbexacerbations. bbThe
bbinflammatory bbresponse bbleads bbto bbtissue bbdamage bbbut bbnot bbanaphylactic
bbshock bb(allergic bbreaction). bbAlthough bbthe bbexact bbetiology bbof bbSLE bbis
bbunknown, bbgenetic, bbethnic, bbenvironmental, bband bbhormonal bbfactors bbplay bba
bbrole bbin bbits bbdevelopment.
The bbnurse bbis bbassessing bba bbclient bbwith bblupus bb(SLE). bbWhich bbclinical
bbmanifestation bbshould bbthe bbnurse bbexpect bbto bbobserve? bbSATA
A) bbPsoriatic bblesions
B) bbRed bbbutterfly bbrash bbon bbthe bbface
C) bbAlopecia
D) bbPainful bbor bbswollen bbjoints
E) bbLeg bband bbeye bbedema bb- bbAnswer bbB, bbC, bbD, bbE
Rationale: bb
, Painful bbswollen bbjoints, bbalopecia, bbred bbbutterfly bbrash bbon bbthe bbface, bband bbleg
bband bbeye bbedema bbare bball bbcharacteristics bbof bbSLE. bbPsoriatic bblesions bbare
bbcaused bbby bbpsoriasis, bbwhich bbis bban bbautoimmune bbdisease bbcharacterized bbby
bbpatches bbof bbabnormal bbskin.
The bbnurse bbis bbassessing bba bbclient bbwith bblupus bb(SLE). bbWhich bbmanifestation
bbshould bbthe bbnurse bbrecognize bbas bba bbresult bbof bbinflammation? bbSATA
A) bbMalaise
B) bbFever
C) bbJoint bbpain
D) bbCough
E) bbMaculopapular bbrash bb- bbAnswer bbA, bbB, bbC, bbE
Rationale: bb
In bbSLE, bbthe bbimmunocomplexes bbthat bbare bbdeposited bbin bbthe bbconnective
bbtissue bbtrigger bban bbinflammatory bbresponse. bbJoint bbpain, bbfever, bbmalaise, bband
bbmaculopapular bbrash bbare bball bbsigns bbof bbthe bbinflammation bbthat bbresult bbfrom
bblocal bbtissue bbdamage. bbA bbcough bbis bba bbsign bbof bbinfection, bbnot bbof
bbinflammation bbresulting bbfrom bbtissue bbdamage.
A bblient bbdiagnosed bbwith bblupus bb(SLE) bbis bbexperiencing bbpulmonary bbinterstitial
bbfibrosis. bbWhich bbclassification bbof bblupus bbshould bbthe bbnurse bbsuspect? bb
A) bbDrug bbinduced
B) bbDiscoid
C) bbCutaneous
D) bbSystemic bb- bbAnswer bbD) bbSystemic
Rationale: bb
The bbclassification bbof bblupus bbthe bbclient bbis bbexperiencing bbis bbsystemic. bbThere
bbare bbthree bbmajor bbclassifications bbof bbSLE: bbdiscoid bbor bbcutaneous, bbsystemic,
bband bbdrug-induced. bbSystemic bblupus bbinvolves bbone bbor bbmore bbof bbthese
bbsystems: bbcardiovascular, bbcentral bbnervous, bbhematologic, bbkidneys, bblungs, bband
bbmusculoskeletal. bbCutaneous bbor bbdiscoid bblupus bbis bblimited bbto bbthe bbskin. bbMany
bbdrugs bbcan bbcause bba bbsyndrome bbthat bbmimics bblupus bb(drug-induced bblupus).
The bbnurse bbis bbcaring bbfor bba bbclient bbwith bblupus bb(SLE). bbWhich bbsystem bbshould
bbthe bbnurse bbconsider bbas bbbeing bbmost bbaffected bbby bbthe bbformation bbof bbimmune
bbcomplexes bband bbtissue bbdamage? bb
A) bbRenal bb
B) bbRespiratory
C) bbCardiac
D) bbIntegumentary bb- bbAnswer bbA) bbRenal
Rationale: bb
When bbthe bbSLE bbautoantibodies bbreact bbwith bbtheir bbcorresponding bbantigen, bbthey
bbform bbimmune bbcomplexes, bbwhich bbare bbthen bbdeposited bbin bbthe bbconnective
ERYTHEMATOSUS (SLE)) (LPN)
QUESTIONS WITH COMPLETE
ANSWERS
The bbnurse bbis bbpreparing bba bbpresentation bbon bbsystemic bblupus bberythematosus
bb(SLE). bbwhich bbstatement bbshould bbthe bbnurse bbinclude? bbSATA
A) bbThe bbetiology bbis bbknown bbto bbbe bblinked bbto bbenvironmental bbfactors
B) bbSLE bbis bba bbresult bbof bbdeposition bbof bbantigen-antibody bbcomplexes bbin
bbconnective bbtissues
C) bbThe bbimmune bbcomplex bbdeposits bbtrigger bban bbinflammatory bbresponse
D) bbThe bbinflammatory bbresponse bbleads bbto bbanaphylactic bbshock
E) bbManifestations bbcan bbbe bbmild bbto bbfatal, bbwith bbremissions bband bbexacerbations
bb- bbAnswer bbB, bbC, bbE
Rationale: bb
The bbpathophysiology bbof bbsystemic bblupus bberythematosus bbis bba bbresult bbof bbthe
bbformation bbof bb
antigen-antibody
immunocomplexes bbthat bbare bbdeposited bbin bbthe bbconnective bbtissue bband bbtrigger
bban bbinflammatory bbresponse. bbThe bbmanifestations bbof bbthe bbdisease bbcan bbbe
bbmild bbto bbfatal, bband bbremissions bbare bbfollowed bbby bbexacerbations. bbThe
bbinflammatory bbresponse bbleads bbto bbtissue bbdamage bbbut bbnot bbanaphylactic
bbshock bb(allergic bbreaction). bbAlthough bbthe bbexact bbetiology bbof bbSLE bbis
bbunknown, bbgenetic, bbethnic, bbenvironmental, bband bbhormonal bbfactors bbplay bba
bbrole bbin bbits bbdevelopment.
The bbnurse bbis bbassessing bba bbclient bbwith bblupus bb(SLE). bbWhich bbclinical
bbmanifestation bbshould bbthe bbnurse bbexpect bbto bbobserve? bbSATA
A) bbPsoriatic bblesions
B) bbRed bbbutterfly bbrash bbon bbthe bbface
C) bbAlopecia
D) bbPainful bbor bbswollen bbjoints
E) bbLeg bband bbeye bbedema bb- bbAnswer bbB, bbC, bbD, bbE
Rationale: bb
, Painful bbswollen bbjoints, bbalopecia, bbred bbbutterfly bbrash bbon bbthe bbface, bband bbleg
bband bbeye bbedema bbare bball bbcharacteristics bbof bbSLE. bbPsoriatic bblesions bbare
bbcaused bbby bbpsoriasis, bbwhich bbis bban bbautoimmune bbdisease bbcharacterized bbby
bbpatches bbof bbabnormal bbskin.
The bbnurse bbis bbassessing bba bbclient bbwith bblupus bb(SLE). bbWhich bbmanifestation
bbshould bbthe bbnurse bbrecognize bbas bba bbresult bbof bbinflammation? bbSATA
A) bbMalaise
B) bbFever
C) bbJoint bbpain
D) bbCough
E) bbMaculopapular bbrash bb- bbAnswer bbA, bbB, bbC, bbE
Rationale: bb
In bbSLE, bbthe bbimmunocomplexes bbthat bbare bbdeposited bbin bbthe bbconnective
bbtissue bbtrigger bban bbinflammatory bbresponse. bbJoint bbpain, bbfever, bbmalaise, bband
bbmaculopapular bbrash bbare bball bbsigns bbof bbthe bbinflammation bbthat bbresult bbfrom
bblocal bbtissue bbdamage. bbA bbcough bbis bba bbsign bbof bbinfection, bbnot bbof
bbinflammation bbresulting bbfrom bbtissue bbdamage.
A bblient bbdiagnosed bbwith bblupus bb(SLE) bbis bbexperiencing bbpulmonary bbinterstitial
bbfibrosis. bbWhich bbclassification bbof bblupus bbshould bbthe bbnurse bbsuspect? bb
A) bbDrug bbinduced
B) bbDiscoid
C) bbCutaneous
D) bbSystemic bb- bbAnswer bbD) bbSystemic
Rationale: bb
The bbclassification bbof bblupus bbthe bbclient bbis bbexperiencing bbis bbsystemic. bbThere
bbare bbthree bbmajor bbclassifications bbof bbSLE: bbdiscoid bbor bbcutaneous, bbsystemic,
bband bbdrug-induced. bbSystemic bblupus bbinvolves bbone bbor bbmore bbof bbthese
bbsystems: bbcardiovascular, bbcentral bbnervous, bbhematologic, bbkidneys, bblungs, bband
bbmusculoskeletal. bbCutaneous bbor bbdiscoid bblupus bbis bblimited bbto bbthe bbskin. bbMany
bbdrugs bbcan bbcause bba bbsyndrome bbthat bbmimics bblupus bb(drug-induced bblupus).
The bbnurse bbis bbcaring bbfor bba bbclient bbwith bblupus bb(SLE). bbWhich bbsystem bbshould
bbthe bbnurse bbconsider bbas bbbeing bbmost bbaffected bbby bbthe bbformation bbof bbimmune
bbcomplexes bband bbtissue bbdamage? bb
A) bbRenal bb
B) bbRespiratory
C) bbCardiac
D) bbIntegumentary bb- bbAnswer bbA) bbRenal
Rationale: bb
When bbthe bbSLE bbautoantibodies bbreact bbwith bbtheir bbcorresponding bbantigen, bbthey
bbform bbimmune bbcomplexes, bbwhich bbare bbthen bbdeposited bbin bbthe bbconnective
