LUPUS NCLEX QUESTIONS WITH
VERIFIED ANSWERS
1. ddA dd26-year-old ddwoman ddhas ddbeen dddiagnosed ddwith ddearly ddsystemic ddlupus
dderythematosus dd(SLE) ddinvolving ddher ddjoints. ddIn ddteaching ddthe ddpatient ddabout
ddthe dddisease, ddthe ddnurse ddincludes ddthe ddinformation ddthat ddSLE ddis dda(n):
A. ddHereditary dddisorder ddof ddwomen ddbut ddusually dddoes ddnot ddshow ddclinical
ddsymptoms ddunless dda ddwoman ddbecomes ddpregnant.
B. ddAutoimmune dddisease ddof ddwomen ddin ddwhich ddantibodies ddare ddformed ddthat
dddestroy ddall ddnucleated ddcells ddin ddthe ddbody.
C. ddDisorder ddof ddimmune ddfunction, ddbut ddit ddis ddextremely ddvariable ddin ddits
ddcourse, ddand ddthere ddis ddno ddway ddto ddpredict ddits ddprogression.
D. ddDisease ddthat ddcauses ddproduction ddof ddantibodies ddthat ddbind ddwith ddcellular
ddestrogen ddreceptors, ddcausing ddan ddinflammatory ddresponse. dd- ddAnswer dd1.
ddAnswer: ddC
Rationale: ddSLE ddhas ddan ddunpredictable ddcourse, ddeven ddwith ddappropriate
ddtreatment. ddWomen ddare ddmore ddat ddrisk ddfor ddSLE, ddbut ddit ddis ddnot ddconfined
ddexclusively ddto ddwomen. ddClinical ddsymptoms ddmay ddworsen ddduring ddpregnancy
ddbut ddare ddnot ddconfined ddto ddpregnancy ddor ddthe ddperinatal ddperiod. ddAll
ddnucleated ddcells ddare ddnot dddestroyed ddby ddthe ddantinuclear ddantibodies. ddThe
ddinflammation ddin ddSLE ddis ddnot ddcaused ddby ddantibody ddbinding ddto ddcellular
ddestrogen ddreceptors.
2. ddA ddpatient ddwith ddan ddacute ddexacerbation ddof ddsystemic ddlupus dderythematosus
dd(SLE) ddis ddhospitalized ddwith ddincapacitating ddfatigue, ddacute ddhand ddand ddwrist
ddpain, ddand ddproteinuria. ddThe ddhealth ddcare ddprovider ddprescribes ddprednisone
dd(Deltasone) dd40 ddmg ddtwice dddaily. ddWhich ddnursing ddaction ddshould ddbe ddincluded
ddin ddthe ddplan ddof ddcare?
A. ddInstitute ddseizure ddprecautions.
B. ddReorient ddto ddtime ddand ddplace ddPRN.
C. ddMonitor ddintake ddand ddoutput.
D. ddPlace ddon ddcardiac ddmonitor. dd- ddAnswer dd2. ddAnswer: ddC
Rationale: ddLupus ddnephritis ddis dda ddcommon ddcomplication ddof ddSLE, ddand ddwhen
ddthe ddpatient ddis ddtaking ddcorticosteroids, ddit ddis ddespecially ddimportant ddto ddmonitor
ddrenal ddfunction. ddThere ddis ddno ddindication ddthat ddthe ddpatient ddis ddexperiencing
ddany ddnervous ddsystem ddor ddcardiac ddproblems ddwith ddthe ddSLE.
, 3. ddA ddpatient ddwith ddsystemic ddlupus dderythematosus dd(SLE) ddwho ddhas dda ddfacial
ddrash ddand ddalopecia ddtells ddthe ddnurse, dd"I ddhate ddthe ddway ddI ddlook! ddI ddnever
ddgo ddanyplace ddexcept ddhere ddto ddthe ddhealth ddclinic." ddAn ddappropriate ddnursing
dddiagnosis ddfor ddthe ddpatient ddis:
A. ddActivity ddintolerance ddrelated ddto ddfatigue ddand ddinactivity.
B. ddImpaired ddskin ddintegrity ddrelated ddto dditching ddand ddskin ddsloughing.
C. ddSocial ddisolation ddrelated ddto ddembarrassment ddabout ddthe ddeffects ddof ddSLE.
D. ddImpaired ddsocial ddinteraction ddrelated ddto ddlack ddof ddsocial ddskills. dd- ddAnswer
dd3. ddAnswer: ddC
Rationale: ddThe ddpatient's ddstatement ddabout ddnot ddgoing ddanyplace ddbecause ddof
ddhating ddthe ddway ddhe ddor ddshe ddlooks ddsupports ddthe dddiagnosis ddof ddsocial
ddisolation ddbecause ddof ddembarrassment ddabout ddthe ddeffects ddof ddthe ddSLE.
ddActivity ddintolerance ddis dda ddpossible ddproblem ddfor ddpatients ddwith ddSLE, ddbut ddthe
ddinformation ddabout ddthis ddpatient dddoes ddnot ddsupport ddthis ddas dda dddiagnosis.
ddThe ddrash ddwith ddSLE ddis ddnonpruritic. ddThere ddis ddno ddevidence ddof ddlack ddof
ddsocial ddskills ddfor ddthis ddpatient.
4. ddA ddpatient ddwith ddpolyarthralgia ddwith ddjoint ddswelling ddand ddpain ddis ddbeing
ddevaluated ddfor ddsystemic ddlupus dderythematosus dd(SLE). ddThe ddnurse ddknows
ddthat ddthe ddserum ddtest ddresult ddthat ddis ddthe ddmost ddspecific ddfor ddSLE ddis ddthe
ddpresence ddof:
A. ddRheumatoid ddfactor.
B. ddAnti-Smith ddantibody dd(Anti-Sm).
C. ddAntinuclear ddantibody dd(ANA).
D. ddLupus dderythematosus dd(LE) ddcell ddprep. dd- ddAnswer dd4. ddAnswer: ddB
Rationale: ddThe ddanti-Sm ddis ddantibody ddfound ddalmost ddexclusively ddin ddSLE. ddThe
ddother ddblood ddtests ddare ddalso ddused ddin ddscreening ddbut ddare ddnot ddas ddspecific
ddto ddSLE.
5. ddFollowing ddinstruction ddfor dda ddpatient ddwith ddnewly dddiagnosed ddsystemic ddlupus
dderythematosus dd(SLE), ddthe ddnurse dddetermines ddthat ddteaching ddabout ddthe
dddisease ddhas ddbeen ddeffective ddwhen ddthe ddpatient ddsays:
A. dd"I ddshould ddexpect ddto ddhave dda ddlow ddfever ddall ddthe ddtime ddwith ddthis
dddisease."
B. dd"I ddneed ddto ddrestrict ddmy ddexposure ddto ddsunlight ddto ddprevent ddan ddacute
ddonset ddof ddsymptoms."
C. dd"I ddshould ddtry ddto ddignore ddmy ddsymptoms ddas ddmuch ddas ddpossible ddand
ddhave dda ddpositive ddoutlook."
D. dd"I ddcan ddexpect dda ddtemporary ddimprovement ddin ddmy ddsymptoms ddif ddI
ddbecome ddpregnant." dd- ddAnswer dd5. ddAnswer: ddB
Rationale: ddSun ddexposure ddis ddassociated ddwith ddSLE ddexacerbation, ddand
ddpatients ddshould dduse ddsunscreen ddwith ddan ddSPF ddof ddat ddleast dd15 ddand ddstay
ddout ddof ddthe ddsun ddbetween dd11:00 ddAM ddand dd3:00 ddPM. ddLow-grade ddfever
VERIFIED ANSWERS
1. ddA dd26-year-old ddwoman ddhas ddbeen dddiagnosed ddwith ddearly ddsystemic ddlupus
dderythematosus dd(SLE) ddinvolving ddher ddjoints. ddIn ddteaching ddthe ddpatient ddabout
ddthe dddisease, ddthe ddnurse ddincludes ddthe ddinformation ddthat ddSLE ddis dda(n):
A. ddHereditary dddisorder ddof ddwomen ddbut ddusually dddoes ddnot ddshow ddclinical
ddsymptoms ddunless dda ddwoman ddbecomes ddpregnant.
B. ddAutoimmune dddisease ddof ddwomen ddin ddwhich ddantibodies ddare ddformed ddthat
dddestroy ddall ddnucleated ddcells ddin ddthe ddbody.
C. ddDisorder ddof ddimmune ddfunction, ddbut ddit ddis ddextremely ddvariable ddin ddits
ddcourse, ddand ddthere ddis ddno ddway ddto ddpredict ddits ddprogression.
D. ddDisease ddthat ddcauses ddproduction ddof ddantibodies ddthat ddbind ddwith ddcellular
ddestrogen ddreceptors, ddcausing ddan ddinflammatory ddresponse. dd- ddAnswer dd1.
ddAnswer: ddC
Rationale: ddSLE ddhas ddan ddunpredictable ddcourse, ddeven ddwith ddappropriate
ddtreatment. ddWomen ddare ddmore ddat ddrisk ddfor ddSLE, ddbut ddit ddis ddnot ddconfined
ddexclusively ddto ddwomen. ddClinical ddsymptoms ddmay ddworsen ddduring ddpregnancy
ddbut ddare ddnot ddconfined ddto ddpregnancy ddor ddthe ddperinatal ddperiod. ddAll
ddnucleated ddcells ddare ddnot dddestroyed ddby ddthe ddantinuclear ddantibodies. ddThe
ddinflammation ddin ddSLE ddis ddnot ddcaused ddby ddantibody ddbinding ddto ddcellular
ddestrogen ddreceptors.
2. ddA ddpatient ddwith ddan ddacute ddexacerbation ddof ddsystemic ddlupus dderythematosus
dd(SLE) ddis ddhospitalized ddwith ddincapacitating ddfatigue, ddacute ddhand ddand ddwrist
ddpain, ddand ddproteinuria. ddThe ddhealth ddcare ddprovider ddprescribes ddprednisone
dd(Deltasone) dd40 ddmg ddtwice dddaily. ddWhich ddnursing ddaction ddshould ddbe ddincluded
ddin ddthe ddplan ddof ddcare?
A. ddInstitute ddseizure ddprecautions.
B. ddReorient ddto ddtime ddand ddplace ddPRN.
C. ddMonitor ddintake ddand ddoutput.
D. ddPlace ddon ddcardiac ddmonitor. dd- ddAnswer dd2. ddAnswer: ddC
Rationale: ddLupus ddnephritis ddis dda ddcommon ddcomplication ddof ddSLE, ddand ddwhen
ddthe ddpatient ddis ddtaking ddcorticosteroids, ddit ddis ddespecially ddimportant ddto ddmonitor
ddrenal ddfunction. ddThere ddis ddno ddindication ddthat ddthe ddpatient ddis ddexperiencing
ddany ddnervous ddsystem ddor ddcardiac ddproblems ddwith ddthe ddSLE.
, 3. ddA ddpatient ddwith ddsystemic ddlupus dderythematosus dd(SLE) ddwho ddhas dda ddfacial
ddrash ddand ddalopecia ddtells ddthe ddnurse, dd"I ddhate ddthe ddway ddI ddlook! ddI ddnever
ddgo ddanyplace ddexcept ddhere ddto ddthe ddhealth ddclinic." ddAn ddappropriate ddnursing
dddiagnosis ddfor ddthe ddpatient ddis:
A. ddActivity ddintolerance ddrelated ddto ddfatigue ddand ddinactivity.
B. ddImpaired ddskin ddintegrity ddrelated ddto dditching ddand ddskin ddsloughing.
C. ddSocial ddisolation ddrelated ddto ddembarrassment ddabout ddthe ddeffects ddof ddSLE.
D. ddImpaired ddsocial ddinteraction ddrelated ddto ddlack ddof ddsocial ddskills. dd- ddAnswer
dd3. ddAnswer: ddC
Rationale: ddThe ddpatient's ddstatement ddabout ddnot ddgoing ddanyplace ddbecause ddof
ddhating ddthe ddway ddhe ddor ddshe ddlooks ddsupports ddthe dddiagnosis ddof ddsocial
ddisolation ddbecause ddof ddembarrassment ddabout ddthe ddeffects ddof ddthe ddSLE.
ddActivity ddintolerance ddis dda ddpossible ddproblem ddfor ddpatients ddwith ddSLE, ddbut ddthe
ddinformation ddabout ddthis ddpatient dddoes ddnot ddsupport ddthis ddas dda dddiagnosis.
ddThe ddrash ddwith ddSLE ddis ddnonpruritic. ddThere ddis ddno ddevidence ddof ddlack ddof
ddsocial ddskills ddfor ddthis ddpatient.
4. ddA ddpatient ddwith ddpolyarthralgia ddwith ddjoint ddswelling ddand ddpain ddis ddbeing
ddevaluated ddfor ddsystemic ddlupus dderythematosus dd(SLE). ddThe ddnurse ddknows
ddthat ddthe ddserum ddtest ddresult ddthat ddis ddthe ddmost ddspecific ddfor ddSLE ddis ddthe
ddpresence ddof:
A. ddRheumatoid ddfactor.
B. ddAnti-Smith ddantibody dd(Anti-Sm).
C. ddAntinuclear ddantibody dd(ANA).
D. ddLupus dderythematosus dd(LE) ddcell ddprep. dd- ddAnswer dd4. ddAnswer: ddB
Rationale: ddThe ddanti-Sm ddis ddantibody ddfound ddalmost ddexclusively ddin ddSLE. ddThe
ddother ddblood ddtests ddare ddalso ddused ddin ddscreening ddbut ddare ddnot ddas ddspecific
ddto ddSLE.
5. ddFollowing ddinstruction ddfor dda ddpatient ddwith ddnewly dddiagnosed ddsystemic ddlupus
dderythematosus dd(SLE), ddthe ddnurse dddetermines ddthat ddteaching ddabout ddthe
dddisease ddhas ddbeen ddeffective ddwhen ddthe ddpatient ddsays:
A. dd"I ddshould ddexpect ddto ddhave dda ddlow ddfever ddall ddthe ddtime ddwith ddthis
dddisease."
B. dd"I ddneed ddto ddrestrict ddmy ddexposure ddto ddsunlight ddto ddprevent ddan ddacute
ddonset ddof ddsymptoms."
C. dd"I ddshould ddtry ddto ddignore ddmy ddsymptoms ddas ddmuch ddas ddpossible ddand
ddhave dda ddpositive ddoutlook."
D. dd"I ddcan ddexpect dda ddtemporary ddimprovement ddin ddmy ddsymptoms ddif ddI
ddbecome ddpregnant." dd- ddAnswer dd5. ddAnswer: ddB
Rationale: ddSun ddexposure ddis ddassociated ddwith ddSLE ddexacerbation, ddand
ddpatients ddshould dduse ddsunscreen ddwith ddan ddSPF ddof ddat ddleast dd15 ddand ddstay
ddout ddof ddthe ddsun ddbetween dd11:00 ddAM ddand dd3:00 ddPM. ddLow-grade ddfever
