AAPD Handbook of Pediatric Dentistry
Ch2. Dental Development, Morphology,
Eruption, and Related Pathologies
Neural Crest Cells: Develop from _______ along lateral margins of neural plate,
undergo extensive migration, resulting in many skeletal and connective tissues including
bone, cartilage, _________, and dermis (but not _______) - answer Ectoderm
dentin but NOT enamel
Dental Lamina: Begins development at _________ weeks of embryonic age, then
differentiates from expansion of basal layer of oral cavity epithelium, where_________
eventually arise. - answer6 weeks
tooth buds
Components of tooth bud/germ (3) - answer Enamel Organ
Dental Papilla
Dental Sac
Dental Lamina Developmental Stage - answer Inductive phenomenon initiates dental
development and is characterized by initiation
Bud Developmental Stage:Initial swellings from dental lamina forming tooth buds,
characterized by _____________ and ______________ - answerBud stage:
proliferation and morphodifferentiation
Cap Developmental stage: Expansion of tooth buds, forming tooth germ, proliferating
into a cap-like appearance. Characterized by (3) - answerCap stage: Proliferation,
histodifferentiation, morphodiffererntiation
Features of Cap stage (4) - answerInner and Outer enamel epithelium
Stellate Reticulum
Dental Papilla
Dental Sac
Stellate reticulum: located in _________ of enamel organ and purpose is to support and
protect ________ - answerSR:
, center of enamel organ
Ameloblasts
Dental papilla: Originates from _________ _________.
Formative organ of _________ and _________ - answerDental Papilla:
from neural crest cells
formative organ of Dentin and primordium of pulp
Dental sac: Gives rise to _________ and _________ - answerCementum and PDL
Early Bell Developmental Stage: Invagination of epithelium deepens, and margins
continue to grow. Form and size develop from differential growth. Characterized by (3) -
answerCharacterized by proliferation, histodifferentiation, and morphodifferentiation
(similar to cap stage)
Early Bell Stage: Stratum intermedium is essential for _________ production -
answerEssential for enamel production
Primordia of permanent teeth (except molars) bud off primary dental lamina and are
called __________
Permanent molars bud off ___________ - answersuccessional dental lamina
primary dental lamina
Advanced Bell Developmental Stage: Differentiation of odontoblasts ________ that of
ameloblasts and future DEJ is outlined.
Basal margin of enamel organ gives rise to ________ - answerdifferentiation of
odontoblast precede ameloblasts
hertwigs epithelial root sheath
Hertwig's Epithelial Root Sheath: Composed of________ and _________ without
stratum intermedium and stellate reticulum.
Root sheath loses continuity once first layer of dentin laid down.
Remnants of root sheath persist as ___________ - answerInner and outer enamel
epithelium
rests of Malassez
Formation of Enamel and Dentin Matrices Developmental Stage: Characterized by
_____________. Regular and rhythmic deposition of matrix of hard dental structures,
taking place in waves from DEJ outward (incisal to cervical).
Ch2. Dental Development, Morphology,
Eruption, and Related Pathologies
Neural Crest Cells: Develop from _______ along lateral margins of neural plate,
undergo extensive migration, resulting in many skeletal and connective tissues including
bone, cartilage, _________, and dermis (but not _______) - answer Ectoderm
dentin but NOT enamel
Dental Lamina: Begins development at _________ weeks of embryonic age, then
differentiates from expansion of basal layer of oral cavity epithelium, where_________
eventually arise. - answer6 weeks
tooth buds
Components of tooth bud/germ (3) - answer Enamel Organ
Dental Papilla
Dental Sac
Dental Lamina Developmental Stage - answer Inductive phenomenon initiates dental
development and is characterized by initiation
Bud Developmental Stage:Initial swellings from dental lamina forming tooth buds,
characterized by _____________ and ______________ - answerBud stage:
proliferation and morphodifferentiation
Cap Developmental stage: Expansion of tooth buds, forming tooth germ, proliferating
into a cap-like appearance. Characterized by (3) - answerCap stage: Proliferation,
histodifferentiation, morphodiffererntiation
Features of Cap stage (4) - answerInner and Outer enamel epithelium
Stellate Reticulum
Dental Papilla
Dental Sac
Stellate reticulum: located in _________ of enamel organ and purpose is to support and
protect ________ - answerSR:
, center of enamel organ
Ameloblasts
Dental papilla: Originates from _________ _________.
Formative organ of _________ and _________ - answerDental Papilla:
from neural crest cells
formative organ of Dentin and primordium of pulp
Dental sac: Gives rise to _________ and _________ - answerCementum and PDL
Early Bell Developmental Stage: Invagination of epithelium deepens, and margins
continue to grow. Form and size develop from differential growth. Characterized by (3) -
answerCharacterized by proliferation, histodifferentiation, and morphodifferentiation
(similar to cap stage)
Early Bell Stage: Stratum intermedium is essential for _________ production -
answerEssential for enamel production
Primordia of permanent teeth (except molars) bud off primary dental lamina and are
called __________
Permanent molars bud off ___________ - answersuccessional dental lamina
primary dental lamina
Advanced Bell Developmental Stage: Differentiation of odontoblasts ________ that of
ameloblasts and future DEJ is outlined.
Basal margin of enamel organ gives rise to ________ - answerdifferentiation of
odontoblast precede ameloblasts
hertwigs epithelial root sheath
Hertwig's Epithelial Root Sheath: Composed of________ and _________ without
stratum intermedium and stellate reticulum.
Root sheath loses continuity once first layer of dentin laid down.
Remnants of root sheath persist as ___________ - answerInner and outer enamel
epithelium
rests of Malassez
Formation of Enamel and Dentin Matrices Developmental Stage: Characterized by
_____________. Regular and rhythmic deposition of matrix of hard dental structures,
taking place in waves from DEJ outward (incisal to cervical).
