LABORATORY REPORT
Activity: Homeostatic Imbalances of Thyroid Function
Name: Theresa Nichole McDaris
Instructor: Adrea Kelley
Date: 08.13.2021
Predictions
1. TSH levels in patients with primary hypothyroidism are
low
2. Thyroxine (T4) levels in patients with primary hypothyroidism are
low
3. TSH levels in patients with secondary hypothyroidism are
low
4. Thyroxine (T4) levels in patients with secondary hypothyroidism are
low
5. TSH levels in patients with hyperthyroidism are
high
6. Thyroxine (T4) levels in patients with hyperthyroidism are
high
Materials and Methods
1. Dependent Variable
blood levels of TSH and thyroxine and accumulation of radioactive iodine in thyroid
2. Independent Variable
thyroid activity
3. Controlled Variables
gender, age
4. Why was RIA used to measure Thyroxine while IRMA was used to measure TSH?
5. How was it used to observe relative amount of iodine accumulated by thyroid gland?
Results
Table 2. Concentration of Thyroxine and Thyroid Stimulating Hormone (TSH) in Blood Serum
Normal Patient 1 Patient 2 Patient 3
Value Status Value Status Value Status
Thyroxine (mg/l) 0.05-0.14 0.25 High 0.01 Low 0.01 Low
TSH (mIU/l) 0.35-4.5 0.13 Low 14.49 High 0.19 Low
Type of thyroid Hyperthyroidism Primary Secondary
disorder Hypothyroidism Hypothyroidism
1. The normal range for total amount of Thyroxine in serum is 0.05 - 0.14 mg/L. For each patient, type in their serum Thyroxine
concentration and indicate if it is lower, within, or higher than the normal range.
a. Patient with primary hypothyroidism
Lower
b. Patient with secondary hypothyroidism
Laboratory Report/ Theresa Nichole McDaris/ Homeostatic Imbalances of Thyroid Function/ Adrea Kelley / 08.13.2021/ Page [1] of [3]