Immunology Exam 1 With Questions
And 100% Correct Answers
What are two examples of phagocytes?
Neutrophils (PMN-polymorpho nuclear) and Macrophages (MO)
True or false: Monocytes are precursors of macrophages.
True. Monocytes are found in blood but when they move into tissues,
they are macrophages.
What cells are important for parasite control, allergy, and
inflammation?
1. mast cell (release histamine when activated)
2. eosinophil (similar function as mast cell but arrive at scene later)
3. basophil (uncommon; function unknown)
4. dendritic cell (internalize pathogens & active T-cells & help
initiate adaptive immune response-serving as a bridge)
What are two types of lymphocytes?
T cells and B cells.
T or F: Plasma cells are B-cells that actively secrete antibodies.
True.
What is the effector function?
A job that a cell has once it is activated
Some functions of the immune response include:
a. recognition of the pathogen or antigen
b. develop "effector" function
What are the main differences between innate immunity and
adaptive immunity?
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Innate immunity: quicker response, use less specific mechanisms
to recognize pathogens, unable to eradicate the pathogen
completely, doesn't provide immunity for reinfection.
Define hematopoiesis.
Hematopoiesis is the generation of blood cells.
T or F: Blood cells and certain tissue cells derive from a common
hematopoietic stem cell.
True. It's pluripotent & self-renewing (can make many copies of
itself)
Immune cells go through which pathways?
Lymphoid and myeloid pathways.
What are examples of granulocytes?
neutrophils, basophils, and eosinophils. They are
polymorphonuclear leukocytes that reside in the blood.
What chemical signals drive the path the cell takes to its final fate?
1. colony stimulating factor (CSF) - GCSF (granulocyte colony
stimulating factor) --> drives the production of neutrophils
2. cytokines
3. growth factors
Blood cell development occurs where in the body?
fetal liver or spleen, and bone marrow (adults only)
What does lymphoid progenitor differentiate into?
1. B cells
2. T cells
3. Natural Killer (NK) cells
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