,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has been
prescribed oralparoxetine hydrochloride. What is the expected
effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body,
circulated through the bloodstream to their sites of action in various body
tissues, and eventually eliminated from the body. Curative agents are given
to cure a disease process. In this case, paroxetine hydrochloride will
control the symptoms but not cure the disorder. Drugs with local effects,
such as sunscreen and local anesthetics, act mainly at the site of
application. Paroxetine hydrochloride is not administered parenterally.
Parenteral agents are administered subcutaneously, intramuscularly, or
intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and
Parenteral TherapiesTOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been cheG mRicAalDlyEm
SoBdOifOieSd.TWhaOt M
.C is another name
for this type of medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally
occurring substances that have been chemically modified. Synthetic drugs
are more standardized in their chemicalcharacteristics, more consistent in
their effects, and less likely to produce allergic reactions. Biotechnology
drugs involve manipulating DNA and RNA and recombining genes into
hybrid molecules that can be inserted into living organisms. Prototype drugs
are the first drug of a particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and
Parenteral TherapiesTOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE