Pharmacology for Anesthesia 1 questions with correct
answers
What is the 2nd leading cause of death? Correct Answer-- cancer
- 1 in 4 deaths
Anthracyclines Correct Answer-Daunorubicin
Doxorubicin
Epirubricin
Idarubicin
Valrubicin
Antitumor Antibiotics Correct Answer-Dactinomycin
Mitomycin C* (acts as an alkylating agent)
Bleomycin
Plicamycin (Discontinued)
Alkylating Agents Correct Answer-Altretamine
Bendamustine
Bisulfan
Carmustine - nitrosurea
Chlorambucil
Cyclophosphamide
,Dacarbazine
Ifosamide
Lomustine - nitrosurea
Mechlorethamine
Melphalan
Mitomycin C* (technically an antitumor antibiotic)
Temozolomide
Thiotepa
Antimetabolites (Anti-folates) Correct Answer-Cepecitabine
Cladribine
Clafarabine
Cytarabine
Fludarabine
Gemcitabine
Nelarabine
5-Flourouracil
6-Thiguanine
6-Mercaptopurine
Methotrexate
Pralatrexate
Anti-microtubule Inhibitors (2) Correct Answer-1. Ixabepilone
, 2. Eribulin
MOA: functions as a microtubule inhibitor and binds directly to B-
tubulin on microtubules, leading to inhibition of mitosis
SE: myelosuppression, peripheral neuropathy, hypersensitivity
Platinum Analogs (3) Correct Answer-1. Carboplatin
2. Cisplatin
3. Oxaplatin
Taxanes (4) Correct Answer-1. Albumin-bound paclitaxel
2. Cabazitaxel
3. Doxetaxel
4. Paclitaxel
MOA: inhibits mitosis and cell division
SE: Myelosuppression & peripheral neuropathy
Topoisomerase 1 Inhibitors (2) Correct Answer-1. Irinotecan
2. Topotecan