Immunization Exam Questions with
Correct Rationales Graded A+
Which of the following antibody classes is the mediator of allergy and anaphylaxis?
A) IgE
B) IgA
C) IgG
D) IgM - Answer: A) IgE
Which of the following describes the role of helper T cells in mounting an immune response to a
vaccine?
A) Directly kills infected cells
B) Presents antigen to antibodies
C) Produces large amounts of antigen specific antibodies
D) Produces cytokines that stimulate B cells to produce antibodies. - Answer: D) Produces cytokines that
stimulate B Cells to produce antibodies
Which of the following is an advantage of passive immunity compared to active immunity?
A) Passive immunity develops in response to infection or after giving a vaccine or toxoid.
B) Passive immunity does not interfere with the development immune responses from live vaccine.
C) Passive immunity protects almost immediately
D) Passive immunity is long-lasting. - Answer: C) Passive immunity protects almost immediately.
Which of the following is NOT an example of active immunity?Administration of high titer immune
globulin
C) Administration of a live attenuated viral vaccine
D) Infection with natural disease. - Answer: B) Administration of high titer immune globulin.
Mary received a blood transfusion following a recent motor vehicle accident. Response to which of the
following vaccines will be most affected by the event?
,A) Tetanus-diptheria
B) Inactivated influenza vaccine
C) Pneumoccoccal polysaccaride vaccine
D) Measles vaccine - Answer: D) Measles Vaccine
A US born 67 year old was recently diagnosed with diabetes. His vaccine records indicate that he
received his Tdap, PPSV23, and flu vaccines in October 2015. What vaccines would you recommed for
him?
A) flu, Hep B series
B) flu, zoster, PCV13, and hep b series
C) flu, zoster, and hep b serie
D) flu, PCV13, varicella, and hep b series. - Answer: B) flu, zoster, PCV13, hep b series
Which of the following is/are true regarding live attenuated vaccines?
A) They re stronger versions of the "wild" vaccines
B) All of the above
C) the injectable live attenuated vaccines usually product immunity with one dose.
D) Live attenuated vaccines generally have milder reactions versus the inactivated vaccines. - Answer: C)
the injectable live attenuated vaccines usually product immunity with one dose.
Joe is a 28 yr old who traveled to Bangkok for a 2 month visit 2 yrs ago. As part of his preparations for
that trip he received a dose of hep A. he has reveived only a Tdap booster since his return. He is now
planning another trip. What vaccines would you recommend?
A) he should start hep a over, getting a dose now and then in 6 months.
B) a double dose of hep a prior to him leaving.
C) half dose of hep a now and another in 6 months.
D) a dose of hep a now to complete the series - Answer: D) A dose of hep A now to complete his series.
Which of the following represent a true contraindication to measles vaccine?
A) moderate or severe acute illness with or without fever.
, B) History of thrombocytopenia
C) Vaccine condidate's mother is pregnant
D) the vaccine candidate is pregnant. - Answer: D) the vaccine candidate is pregnant
A 26 yr old female received the second dose in her series of varicella 2 weeks ago. today to stepped on a
nail. Her last tetnus-diptheria was 6 years ago. Which of the following is appropriate?
A) No booster is necessary
B) give Td in 2 weeks
C) Give DTaP ow
D) Give Tdap now - Answer: D) give Tdap now
Which of the following is a contraindication to receiving a live vaccine?
A) Allergy to penicillin
B) predisone 40 mg qd
C) diabetic patient
D) chronic liver disease - Answer: B) prednisone 40 mg qd.
Is the following statement true or false? Increasing the interval b/w doses of a multi-dose vaccine does
NOT diminish the effectiveness of the vaccine. - Answer: True
Which of the following is a condidate for the HPV9 vaccine?
A) 27 yr old male on prednisone 10 mg daily
B) 35 year old health male
C) 27 year old healthy female
D) 11 year old healthy male - Answer: D) 11 yr old healthy male
True or False. Joe is a 20 yr old patient stating that he remembers having Cx Px when he was young He is
a candidate for the varicella vaccine. - Answer: True
Correct Rationales Graded A+
Which of the following antibody classes is the mediator of allergy and anaphylaxis?
A) IgE
B) IgA
C) IgG
D) IgM - Answer: A) IgE
Which of the following describes the role of helper T cells in mounting an immune response to a
vaccine?
A) Directly kills infected cells
B) Presents antigen to antibodies
C) Produces large amounts of antigen specific antibodies
D) Produces cytokines that stimulate B cells to produce antibodies. - Answer: D) Produces cytokines that
stimulate B Cells to produce antibodies
Which of the following is an advantage of passive immunity compared to active immunity?
A) Passive immunity develops in response to infection or after giving a vaccine or toxoid.
B) Passive immunity does not interfere with the development immune responses from live vaccine.
C) Passive immunity protects almost immediately
D) Passive immunity is long-lasting. - Answer: C) Passive immunity protects almost immediately.
Which of the following is NOT an example of active immunity?Administration of high titer immune
globulin
C) Administration of a live attenuated viral vaccine
D) Infection with natural disease. - Answer: B) Administration of high titer immune globulin.
Mary received a blood transfusion following a recent motor vehicle accident. Response to which of the
following vaccines will be most affected by the event?
,A) Tetanus-diptheria
B) Inactivated influenza vaccine
C) Pneumoccoccal polysaccaride vaccine
D) Measles vaccine - Answer: D) Measles Vaccine
A US born 67 year old was recently diagnosed with diabetes. His vaccine records indicate that he
received his Tdap, PPSV23, and flu vaccines in October 2015. What vaccines would you recommed for
him?
A) flu, Hep B series
B) flu, zoster, PCV13, and hep b series
C) flu, zoster, and hep b serie
D) flu, PCV13, varicella, and hep b series. - Answer: B) flu, zoster, PCV13, hep b series
Which of the following is/are true regarding live attenuated vaccines?
A) They re stronger versions of the "wild" vaccines
B) All of the above
C) the injectable live attenuated vaccines usually product immunity with one dose.
D) Live attenuated vaccines generally have milder reactions versus the inactivated vaccines. - Answer: C)
the injectable live attenuated vaccines usually product immunity with one dose.
Joe is a 28 yr old who traveled to Bangkok for a 2 month visit 2 yrs ago. As part of his preparations for
that trip he received a dose of hep A. he has reveived only a Tdap booster since his return. He is now
planning another trip. What vaccines would you recommend?
A) he should start hep a over, getting a dose now and then in 6 months.
B) a double dose of hep a prior to him leaving.
C) half dose of hep a now and another in 6 months.
D) a dose of hep a now to complete the series - Answer: D) A dose of hep A now to complete his series.
Which of the following represent a true contraindication to measles vaccine?
A) moderate or severe acute illness with or without fever.
, B) History of thrombocytopenia
C) Vaccine condidate's mother is pregnant
D) the vaccine candidate is pregnant. - Answer: D) the vaccine candidate is pregnant
A 26 yr old female received the second dose in her series of varicella 2 weeks ago. today to stepped on a
nail. Her last tetnus-diptheria was 6 years ago. Which of the following is appropriate?
A) No booster is necessary
B) give Td in 2 weeks
C) Give DTaP ow
D) Give Tdap now - Answer: D) give Tdap now
Which of the following is a contraindication to receiving a live vaccine?
A) Allergy to penicillin
B) predisone 40 mg qd
C) diabetic patient
D) chronic liver disease - Answer: B) prednisone 40 mg qd.
Is the following statement true or false? Increasing the interval b/w doses of a multi-dose vaccine does
NOT diminish the effectiveness of the vaccine. - Answer: True
Which of the following is a condidate for the HPV9 vaccine?
A) 27 yr old male on prednisone 10 mg daily
B) 35 year old health male
C) 27 year old healthy female
D) 11 year old healthy male - Answer: D) 11 yr old healthy male
True or False. Joe is a 20 yr old patient stating that he remembers having Cx Px when he was young He is
a candidate for the varicella vaccine. - Answer: True
