APHA Immunization Exam Questions
with Correct Rationales Graded A+
Which of the following vaccines may be administered to boys and young men aged 9 through 26 years
to reduce the likelihood of acquiring genital warts? - Answer: HPV9
Barbara is a 60-year-old woman who presents to the pharmacy for two vaccines: HZV and IIV. Which of
the following are the appropriate doses and routes for administering these vaccines to this patient? -
Answer: HZV 0.65 mL subcutaneously; IIV 0.5 mL intramuscularly.
Which of the following patients would be a candidate for PPSV23? - Answer: 25-year-old man who
smokes cigarettes.
Why should refrigerated vaccines be stored in the middle of the refrigerator? - Answer: There are fewer
temperature fluctuations
When looking at the schedule for vaccines that might be indicated for children and adolescents aged 18
years or younger based on medical indications, what does the orange bar represent? - Answer:
Precautions for vaccination
Which of the following statements is true regarding how vaccines evoke an immune response? - Answer:
The antigen in the vaccine activates B cells, which produce antigen-specific antibodies and memory cells.
How often are the Healthy People targets for vaccination rates updated? - Answer: *not* every year
According to ACIP recommendations, which of the following needle lengths would be appropriate for
administering HZV to an adult patient? - Answer: 5/8 inch
Which vaccine does ACIP recommend for all college freshmen, aged 21 years or younger, living in
dormitories, who have not been previously vaccinated? - Answer: mcv4
,What is the time interval for which the development of Guillain-Barré syndrome following influenza
vaccination would result in a precaution for future influenza vaccines? - Answer: Within 6 weeks
A health care provider who has not been vaccinated against hepatitis B is stuck by a contaminated
needle after administering an immunization to a hepatitis B-positive patient. In addition to hepatitis B
vaccine, the health care provider also should receive hepatitis B Immunoglobulin (HBIG) as postexposure
prophylaxis because the HBIG provides: - Answer: Prompt immunity
Alex is a 32-year-old man who is scheduled to travel to a country where hepatitis A is endemic. He
leaves in 3 weeks and will be gone a month. He received his first dose of hepatitis A vaccine today. Alex
should be counseled to return for his second dose of hepatitis A vaccine: - Answer: In 6 months
What is the type of immunity that occurs when a pregnant woman is vaccinated with Tdap to protect
the infant from pertussis after birth? - Answer: Passive immunity
The monitoring system that health care providers should use to report serious adverse events after
vaccination is: - Answer: VAERS
If a vial of influenza vaccine is left out of the refrigerator on the pharmacy counter overnight, what
should be done with the vaccine? - Answer: Mark "do not use," place in the refrigerator, and call the
manufacturer for further guidance.
For which age group is the adjuvanted inactivated influenza vaccine approved? - Answer: 65 years and
older
Which of the following statements about establishing clinics for administering vaccines is true? -
Answer: Technicians can administer screening questionnaires and distribute VISs.
If pharmacists are called upon to assist with vaccination efforts following a natural disaster, which
vaccine is likely to be needed by many of the victims? - Answer: Tetanus
Which of the following patients should receive the MMR vaccine? - Answer: A pharmacist born in 1975
with documentation of 1 dose of MMR vaccine.
,Prior to the introduction of a vaccine, what was the leading cause of bacterial meningitis in children
younger than 5 years of age? - Answer: Haemophilus influenzae type b.
According to the Advisory Committee on Immunization Practices (ACIP), which of the following would be
considered adequate evidence of immunity to varicella, indicating that administration of varicella
vaccine is unnecessary? - Answer: Diagnosis of chickenpox by a health care provider.
Even though state laws may have specific mandates, how long should pharmacists maintain records of
immunizations? - Answer: For a patient's lifetime
Justin is a healthy 16-year-old boy who has no documentation of varicella vaccine or history of the
disease. He should receive - Answer: 2 doses of varicella vaccine separated by at least 4 weeks.
The childhood/adolescent and adult immunization schedules are updated and published annually during
which months? - Answer: January or February.
Aiden is a 6-month-old healthy boy with no known allergies. He has received vaccinations in the past
with no reported adverse reactions. Aiden's father asks about having his son vaccinated against
influenza. The most appropriate response would be to inform the father that Aiden: - Answer: Should
receive 1 dose of IIV4 today followed by a second dose of IIV4 administered 4 weeks later
Which of the following patients are appropriate candidates for the 2-dose schedule of HPV9? - Answer:
11 year-old girl with no medical conditions, series has not been started
What is the standard dose of epinephrine for managing anaphylaxis? - Answer: 0.01 mg per kg body
weight, up to a maximum of 0.5 mg.
Which of the following statements about live attenuated vaccines is true? - Answer: They should
generally be avoided in immunocompromised individuals.
Upon giving a VIS to a patient who is to receive a vaccine cover under the National Childhood Vaccine
Injury Act, what must be documented? - Answer: The date the VIS was given to the patient or caregiver
and the date printed on the VIS.
, RotaTeq (RV5) should be administered as a: - Answer: 3-dose series to infants at 2, 4, and 6 months of
age
Which of the following best describes how to administer MMR vaccine to an adult patient weighing 210
lb? - Answer: Inject subcutaneously at a 45° angle in the outer aspect of the upper arm
According to ACIP recommendations, HZV is indicated for the prevention of herpes zoster in adults aged:
- Answer: 60 years and older.
Federal law makes offering an annual influenza vaccination a requirement for continued federal funding
in which setting? - Answer: Long-term care facilities.
Which of the following patients is a candidate for both MenACWY and MenB vaccines? - Answer: A 10
year-old who just had his spleen removed.
A 69 year-old man received Td vaccination 4 years ago. He is preparing to travel to see his newborn
granddaughter next month. Which of the following vaccines containing tetanus, diphtheria, and/or
pertussis would be most appropriate for him? - Answer: Tdap
Which of the following key questions is important to ask a patient before administering IIV? - Answer:
Are you sick today?
Which of these vaccines is an inactivated vaccine? - Answer: Tdap
Which of these vaccines is a live attenuated vaccine? - Answer: Zoster
Which viruses are associated with the development of cancer? - Answer: Human papillomavirus and
hepatitis B virus.
What is the minimum needle length recommended for administering HepB vaccine to an adult patient
weighing 130 lb? - Answer: 1 inch
with Correct Rationales Graded A+
Which of the following vaccines may be administered to boys and young men aged 9 through 26 years
to reduce the likelihood of acquiring genital warts? - Answer: HPV9
Barbara is a 60-year-old woman who presents to the pharmacy for two vaccines: HZV and IIV. Which of
the following are the appropriate doses and routes for administering these vaccines to this patient? -
Answer: HZV 0.65 mL subcutaneously; IIV 0.5 mL intramuscularly.
Which of the following patients would be a candidate for PPSV23? - Answer: 25-year-old man who
smokes cigarettes.
Why should refrigerated vaccines be stored in the middle of the refrigerator? - Answer: There are fewer
temperature fluctuations
When looking at the schedule for vaccines that might be indicated for children and adolescents aged 18
years or younger based on medical indications, what does the orange bar represent? - Answer:
Precautions for vaccination
Which of the following statements is true regarding how vaccines evoke an immune response? - Answer:
The antigen in the vaccine activates B cells, which produce antigen-specific antibodies and memory cells.
How often are the Healthy People targets for vaccination rates updated? - Answer: *not* every year
According to ACIP recommendations, which of the following needle lengths would be appropriate for
administering HZV to an adult patient? - Answer: 5/8 inch
Which vaccine does ACIP recommend for all college freshmen, aged 21 years or younger, living in
dormitories, who have not been previously vaccinated? - Answer: mcv4
,What is the time interval for which the development of Guillain-Barré syndrome following influenza
vaccination would result in a precaution for future influenza vaccines? - Answer: Within 6 weeks
A health care provider who has not been vaccinated against hepatitis B is stuck by a contaminated
needle after administering an immunization to a hepatitis B-positive patient. In addition to hepatitis B
vaccine, the health care provider also should receive hepatitis B Immunoglobulin (HBIG) as postexposure
prophylaxis because the HBIG provides: - Answer: Prompt immunity
Alex is a 32-year-old man who is scheduled to travel to a country where hepatitis A is endemic. He
leaves in 3 weeks and will be gone a month. He received his first dose of hepatitis A vaccine today. Alex
should be counseled to return for his second dose of hepatitis A vaccine: - Answer: In 6 months
What is the type of immunity that occurs when a pregnant woman is vaccinated with Tdap to protect
the infant from pertussis after birth? - Answer: Passive immunity
The monitoring system that health care providers should use to report serious adverse events after
vaccination is: - Answer: VAERS
If a vial of influenza vaccine is left out of the refrigerator on the pharmacy counter overnight, what
should be done with the vaccine? - Answer: Mark "do not use," place in the refrigerator, and call the
manufacturer for further guidance.
For which age group is the adjuvanted inactivated influenza vaccine approved? - Answer: 65 years and
older
Which of the following statements about establishing clinics for administering vaccines is true? -
Answer: Technicians can administer screening questionnaires and distribute VISs.
If pharmacists are called upon to assist with vaccination efforts following a natural disaster, which
vaccine is likely to be needed by many of the victims? - Answer: Tetanus
Which of the following patients should receive the MMR vaccine? - Answer: A pharmacist born in 1975
with documentation of 1 dose of MMR vaccine.
,Prior to the introduction of a vaccine, what was the leading cause of bacterial meningitis in children
younger than 5 years of age? - Answer: Haemophilus influenzae type b.
According to the Advisory Committee on Immunization Practices (ACIP), which of the following would be
considered adequate evidence of immunity to varicella, indicating that administration of varicella
vaccine is unnecessary? - Answer: Diagnosis of chickenpox by a health care provider.
Even though state laws may have specific mandates, how long should pharmacists maintain records of
immunizations? - Answer: For a patient's lifetime
Justin is a healthy 16-year-old boy who has no documentation of varicella vaccine or history of the
disease. He should receive - Answer: 2 doses of varicella vaccine separated by at least 4 weeks.
The childhood/adolescent and adult immunization schedules are updated and published annually during
which months? - Answer: January or February.
Aiden is a 6-month-old healthy boy with no known allergies. He has received vaccinations in the past
with no reported adverse reactions. Aiden's father asks about having his son vaccinated against
influenza. The most appropriate response would be to inform the father that Aiden: - Answer: Should
receive 1 dose of IIV4 today followed by a second dose of IIV4 administered 4 weeks later
Which of the following patients are appropriate candidates for the 2-dose schedule of HPV9? - Answer:
11 year-old girl with no medical conditions, series has not been started
What is the standard dose of epinephrine for managing anaphylaxis? - Answer: 0.01 mg per kg body
weight, up to a maximum of 0.5 mg.
Which of the following statements about live attenuated vaccines is true? - Answer: They should
generally be avoided in immunocompromised individuals.
Upon giving a VIS to a patient who is to receive a vaccine cover under the National Childhood Vaccine
Injury Act, what must be documented? - Answer: The date the VIS was given to the patient or caregiver
and the date printed on the VIS.
, RotaTeq (RV5) should be administered as a: - Answer: 3-dose series to infants at 2, 4, and 6 months of
age
Which of the following best describes how to administer MMR vaccine to an adult patient weighing 210
lb? - Answer: Inject subcutaneously at a 45° angle in the outer aspect of the upper arm
According to ACIP recommendations, HZV is indicated for the prevention of herpes zoster in adults aged:
- Answer: 60 years and older.
Federal law makes offering an annual influenza vaccination a requirement for continued federal funding
in which setting? - Answer: Long-term care facilities.
Which of the following patients is a candidate for both MenACWY and MenB vaccines? - Answer: A 10
year-old who just had his spleen removed.
A 69 year-old man received Td vaccination 4 years ago. He is preparing to travel to see his newborn
granddaughter next month. Which of the following vaccines containing tetanus, diphtheria, and/or
pertussis would be most appropriate for him? - Answer: Tdap
Which of the following key questions is important to ask a patient before administering IIV? - Answer:
Are you sick today?
Which of these vaccines is an inactivated vaccine? - Answer: Tdap
Which of these vaccines is a live attenuated vaccine? - Answer: Zoster
Which viruses are associated with the development of cancer? - Answer: Human papillomavirus and
hepatitis B virus.
What is the minimum needle length recommended for administering HepB vaccine to an adult patient
weighing 130 lb? - Answer: 1 inch
