BMTCN PRACTICE TEST A QUESTIONS & ANSWERS
Which of the following medications should a patient taking cyclosporine avoid following
an allogenic HSCT?
A. Torsemide
B. Bumetanide
C. Spironolactone
D. Furosemide - Answers- C. Patients taking cyclosporine should avoid potassium
sparing diuretics such as spironolactone.
How is bronchiolitis obliterans diagnosed?
A. Pulmonary function test
B. Bronchoalveolar lavage
C. Computed tomography scan
D. Chest x-ray - Answers- A. Pulmonary function test. Used to diagnose bronchiolitis
obliterans.
Which of the following medications is a chemokine antagonist that is used for stem cell
mobilization?
A. Plerixafor
B. Filgrastim
C. Erythropoietin
D. Sargramostim - Answers- A. Plerixafor is the first chemokine antagonist for stem cell
mobilization.
Which of the following immunizations should an asplenic child who had a transplant
receive?
A. Tetanus
B. Cytomegalovirus
C. Pneumococcal
D. Varicella - Answers- C. Asplenic children should receive a pneumococcal
immunization after a transplant.
Why is the additive DMSO used during stem cell processing?
A. Prevents cell damage during the freezing and thawing of autologous stem cells.
B. Facilitates purging of malignant cells in autologous transplants
C. Prevents GVHD by removing cytokines from mismatched stem cells
D. Prevents coagulation in bags of unrelated fresh bone marrow and stem cells -
Answers- A. DMSO is an additive used to prevent damage to cells during freezing or
thawing.
How many days should lapse between dental extraction and the start of conditioning?
A. 28 to 30 days
B. 10 to 14 days
C. 5 to 7 days
, D. 18 to 21 days - Answers- B. In order to prevent potential complications, dental
extraction and healing should be complete 10 to 14 days prior to beginning a
conditioning regimen or transplantation.
Immunoglobulins are secreted by which type of cell?
A. Natural Killer
B. Megakaryocyte
C. B-Lymphocyte
D. T-Lymphocyte - Answers- C. B-Lymphocytes synthesize and secrete
immunoglobulins.
What is a female patient experiencing who begins to have a dense, coarse, and
excessive hair growth on the face, neck, and chest after taking vincristine?
A. Hirsutism
B. Paronychia
C. Trichomegaly
D. Hyperpigmentation - Answers- A. Hirsutism is the term for abnormal hair growth that
follows a number of chemotherapy drugs.
How should the healthcare team address the psychosocial needs of transplant patients
and caregivers?
A. Implement a quality improvement plan
B. Develop a comprehensive educational program
C. Report complications to FACT
D. Consult with the American Society of Hematology - Answers- B. Members of the
team must work together to educate the patient, family, and caregiver through each step
of the transplant.
What type of chimerism describes the state that exists when a donor
lymphohematopoietic system completely replaces that of the recipient?
A. Incomplete
B. Split
C. Tetragametic
D. Mixed - Answers- D. Mixed chimerism is the term used to describe the coexistence
of a donor and recipient's lymphohematopoietic system.
What is the first step in selecting a donor for an allogenic HSCT?
A. Histocompatibility testing
B. ABO blood-typing
C. Psychosocial assessment
D. Physical examination - Answers- A. The first step in selecting a donor for an
allogenic HSCT is HLA testing to determine if there is a match.
Which of the following is a disadvantage for the host of the matched sibling/related
donor stem cells?
A. Increased rate of infection
Which of the following medications should a patient taking cyclosporine avoid following
an allogenic HSCT?
A. Torsemide
B. Bumetanide
C. Spironolactone
D. Furosemide - Answers- C. Patients taking cyclosporine should avoid potassium
sparing diuretics such as spironolactone.
How is bronchiolitis obliterans diagnosed?
A. Pulmonary function test
B. Bronchoalveolar lavage
C. Computed tomography scan
D. Chest x-ray - Answers- A. Pulmonary function test. Used to diagnose bronchiolitis
obliterans.
Which of the following medications is a chemokine antagonist that is used for stem cell
mobilization?
A. Plerixafor
B. Filgrastim
C. Erythropoietin
D. Sargramostim - Answers- A. Plerixafor is the first chemokine antagonist for stem cell
mobilization.
Which of the following immunizations should an asplenic child who had a transplant
receive?
A. Tetanus
B. Cytomegalovirus
C. Pneumococcal
D. Varicella - Answers- C. Asplenic children should receive a pneumococcal
immunization after a transplant.
Why is the additive DMSO used during stem cell processing?
A. Prevents cell damage during the freezing and thawing of autologous stem cells.
B. Facilitates purging of malignant cells in autologous transplants
C. Prevents GVHD by removing cytokines from mismatched stem cells
D. Prevents coagulation in bags of unrelated fresh bone marrow and stem cells -
Answers- A. DMSO is an additive used to prevent damage to cells during freezing or
thawing.
How many days should lapse between dental extraction and the start of conditioning?
A. 28 to 30 days
B. 10 to 14 days
C. 5 to 7 days
, D. 18 to 21 days - Answers- B. In order to prevent potential complications, dental
extraction and healing should be complete 10 to 14 days prior to beginning a
conditioning regimen or transplantation.
Immunoglobulins are secreted by which type of cell?
A. Natural Killer
B. Megakaryocyte
C. B-Lymphocyte
D. T-Lymphocyte - Answers- C. B-Lymphocytes synthesize and secrete
immunoglobulins.
What is a female patient experiencing who begins to have a dense, coarse, and
excessive hair growth on the face, neck, and chest after taking vincristine?
A. Hirsutism
B. Paronychia
C. Trichomegaly
D. Hyperpigmentation - Answers- A. Hirsutism is the term for abnormal hair growth that
follows a number of chemotherapy drugs.
How should the healthcare team address the psychosocial needs of transplant patients
and caregivers?
A. Implement a quality improvement plan
B. Develop a comprehensive educational program
C. Report complications to FACT
D. Consult with the American Society of Hematology - Answers- B. Members of the
team must work together to educate the patient, family, and caregiver through each step
of the transplant.
What type of chimerism describes the state that exists when a donor
lymphohematopoietic system completely replaces that of the recipient?
A. Incomplete
B. Split
C. Tetragametic
D. Mixed - Answers- D. Mixed chimerism is the term used to describe the coexistence
of a donor and recipient's lymphohematopoietic system.
What is the first step in selecting a donor for an allogenic HSCT?
A. Histocompatibility testing
B. ABO blood-typing
C. Psychosocial assessment
D. Physical examination - Answers- A. The first step in selecting a donor for an
allogenic HSCT is HLA testing to determine if there is a match.
Which of the following is a disadvantage for the host of the matched sibling/related
donor stem cells?
A. Increased rate of infection
