PT 623 - Myelodysplasia (Spina Bifida)
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What is myelodysplasia? - ✔✔defective development of any part of the
spinal cord related to abnormal neurulation or canalization
What is the most common neural tube defect in the US? -
✔✔myelodysplasia
What is spina bifida occulta? - ✔✔spinal cord does not protrude, tufts of
hair are found at the site of neural tube defect, no neurological defects
What is spina bifida meningocele? - ✔✔spinal cord is normal, but meninges
protrude through opening, rare to see neurological defects
What is spina bifida myelomeningocele? - ✔✔spinal cord and meninges
are damaged and protrude into opening, permanent neurological damage
What are the etiologies of spina bifida? - ✔✔- genetic problems
- exposure to hazardous chemicals and other substances
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- maternal lack of proper vitamin B-9 (folic acid) and nutrients in the diet in
1st trimester
- infection
- prescription drugs (ex. valproic acid)
- alcohol consumption
What are the MSK impairments that are seen with myelodysplasia? - ✔✔-
spinal deformities (scoliosis, kyphosis,. hyperlordosis)
- hip dislocation/subluxation
- foot deformities (ex. clubfoot)
- contractures
- osteoporosis
How is the motor level of myelodysplasia named? - ✔✔by the lowest intact,
functional neuromuscular segment
What are the neuromuscular impairments seen with myelomeningocele? -
✔✔- motor paralysis
- sensory deficits
- neurogenic bowel and bladder
- spasticity
- hydrocephalus
- arnold-chiari malformation