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PHAR 100 Final Exam Questions and
Answers 100% Solved | Graded A+
Path of drug from when it enters to exits the body - ✔✔1. Absorption
2. Distribution
3. Metabolism
4. Excretion
Absorption - ✔✔the movement of the drug from the site of administration
into the bloodstream
Distribution - ✔✔the movement of a drug from the blood to the site of action
and other tissues
Metabolism - ✔✔the conversion of a drug to a different chemical
compound.
Excretion - ✔✔moving of the drug and its metabolites out of the body
Routes of drug administration - ✔✔1. Topical
- On the skin
-Transdermal
-Inhalation
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2. Enteral
-Oral
-Suppository
-Buccal
3.Parenteral
-IV
-IM
-Subcutaneous
Why and how do adverse drug reactions occur? - ✔✔Example: a receptor
is activated in a blood vessel by a drug designed to treat hypertension. The
rector is activated by the ligand that is bound to it, and the blood pressure
is lowered. However, this receptor may located in other areas of the body.
The subsequent activation of this receptor in other areas of the body is an
example of an adverse effect.
Adverse effects - ✔✔1. Extension of therapeutic effect
2. Unrelated to main drug action
3. Allergic reaction
4. Dependence and addiction
, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
5. Teratogenesis
6. Adverse biotransformation reactions
Why does drug variability exist - ✔✔1. Genetic Factors
2. Environmental factors
3. Diseased states (cardiovascular or kidney disease for example)
4. Altered Physiological state
-pregnant or elderly
5. Other drugs present (competition)
The process of developing a new drug - ✔✔1. Pre-clinical testing
-safety and potential efficacy in lab animals
2. Phase I Clinical Trial
-safety and tolerability in healthy volunteers
3. Phase II
-effectiveness and safety in a small number of patients
4. Phase III
-effectiveness and safety in a large number of patients
PHAR 100 Final Exam Questions and
Answers 100% Solved | Graded A+
Path of drug from when it enters to exits the body - ✔✔1. Absorption
2. Distribution
3. Metabolism
4. Excretion
Absorption - ✔✔the movement of the drug from the site of administration
into the bloodstream
Distribution - ✔✔the movement of a drug from the blood to the site of action
and other tissues
Metabolism - ✔✔the conversion of a drug to a different chemical
compound.
Excretion - ✔✔moving of the drug and its metabolites out of the body
Routes of drug administration - ✔✔1. Topical
- On the skin
-Transdermal
-Inhalation
,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
2. Enteral
-Oral
-Suppository
-Buccal
3.Parenteral
-IV
-IM
-Subcutaneous
Why and how do adverse drug reactions occur? - ✔✔Example: a receptor
is activated in a blood vessel by a drug designed to treat hypertension. The
rector is activated by the ligand that is bound to it, and the blood pressure
is lowered. However, this receptor may located in other areas of the body.
The subsequent activation of this receptor in other areas of the body is an
example of an adverse effect.
Adverse effects - ✔✔1. Extension of therapeutic effect
2. Unrelated to main drug action
3. Allergic reaction
4. Dependence and addiction
, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
5. Teratogenesis
6. Adverse biotransformation reactions
Why does drug variability exist - ✔✔1. Genetic Factors
2. Environmental factors
3. Diseased states (cardiovascular or kidney disease for example)
4. Altered Physiological state
-pregnant or elderly
5. Other drugs present (competition)
The process of developing a new drug - ✔✔1. Pre-clinical testing
-safety and potential efficacy in lab animals
2. Phase I Clinical Trial
-safety and tolerability in healthy volunteers
3. Phase II
-effectiveness and safety in a small number of patients
4. Phase III
-effectiveness and safety in a large number of patients
