Test Bankfor Pharmacotherapeutics for AdvancedPractice A
v v v v v v v
Practical Approach 5th Edition By Virginia Poole Arcangelo,
v v v v v v v v
Andrew M Peterson, Veronica Wilbur, Tep M. Kang/ All
v v v v v v v v v
Chapters Covered – Latest Update 2024. v v v v v
Nurse practitioner prescriptive authority is regulated by:
v v v v v v
1. The National Council of State Boards of Nursing
v v v v v v v
2. The U.S. Drug Enforcement Administration
v v v v
3. The State Board of Nursing for each state
v v v v v v v
4. The State Board of Pharmacy - Correct Answer - 3. The State Board of Nursing for each state
v v v v v v v v v v v v v v v v v
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber include:
v v v v v v v v v v v v v v
1. Nurses know more about Pharmacology than other prescribers because they take it both in their basic
v v v v v v v v v v v v v v v
nursing program and in their APRN program.
v v v v v v v
2. Nurses care for the patient from a holistic approach and include the patient in decision making
v v v v v v v v v v v v v v v
regarding their care.
v v v
3. APRNs are less likely to prescribe narcotics and other controlled substances.
v v v v v v v v v v
4. APRNs are able to prescribe independently in all states, whereas a physician's assistant needs to have a
v v v v v v v v v v v v v v v v
physician supervising their practice. - Correct Answer - 2. Nurses care for the patient from a holistic
v v v v v v v v v v v v v v v v v
approach and include the patient in decision making regarding their care.
v v v v v v v v v v v
Clinical judgment in prescribing includes:
v v v v
1. Factoring in the cost to the patient of the medication prescribed
v v v v v v v v v v
2. Always prescribing the newest medication available for the disease process
v v v v v v v v v
3. Handing out drug samples to poor patients v v v v v v
4. Prescribing all generic medications to cut costs - Correct Answer - 1. Factoring in the cost to the
v v v v v v v v v v v v v v v v v
patient of the medication prescribed
v v v v v
pg. 1
v
,Criteria for choosing an effective drug for a disorder include:
v v v v v v v v v
1. Asking the patient what drug they think would work best for them
v v v v v v v v v v v
2. Consulting nationally recognized guidelines for disease managementv v v v v v
3. Prescribing medications that are available as samples before writing a prescription
v v v v v v v v v v
4. Following U.S. Drug Enforcement Administration guidelines for prescribing - Correct Answer - 2.
v v v v v v v v v v v v
Consulting nationally recognized guidelines for disease management
v v v v v v v
Nurse practitioner practice may thrive under health-care reform because of:
v v v v v v v v v
1. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes
v v v v v v v v v v v v
2. The fact that nurse practitioners will be able to practice independently
v v v v v v v v v v
3. The fact that nurse practitioners will have full reimbursement under health-care reform
v v v v v v v v v v v
4. The ability to shift accountability for Medicaid to the state level - Correct Answer - 1. The
v v v v v v v v v v v v v v v v
demonstrated ability of nurse practitioners to control costs and improve patient outcomes
v v v v v v v v v v v v
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This is
v v v v v v v v v v
critical to prescribing because:
v v v v
1. Distribution of drugs to target tissue may be affected. v v v v v v v v
2. The solubility of the drug will not match the site of absorption.
v v v v v v v v v v v
3. There will be less free drug available to generate an effect.
v v v v v v v v v v
4. Drugs bound to albumin are readily excreted by the kidneys. - Correct Answer - 1. Distribution of drugs to
v v v v v v v v v v v v v v v v v v
target tissue may be affected.
v v v v v
Drugs that have a significant first-pass effect:
v v v v v v
1. Must be given by the enteral (oral) route only
v v v v v v v v
2. Bypass the hepatic circulation v v v
3. Are rapidly metabolized by the liver and may have little if any desired action
v v v v v v v v v v v v v
pg. 2v
,4. Are converted by the liver to more active and fat-soluble forms - Correct Answer - 3. Are rapidly
v v v v v v v v v v v v v v v v v
metabolized by the liver and may have little if any desired action
v v v v v v v v v v v v
The route of excretion of a volatile drug will likely be the:
v v v v v v v v v v v
1. Kidneys
2. Lungs
3. Bile and feces v v
4. Skin - Correct Answer - 2. Lungs
v v v v v v
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir of v v v v v v v v v v v v
the drug. Storage reservoirs:
v v v v
1. Assure that the drug will reach its intended target tissue
v v v v v v v v v
2. Are the reason for giving loading doses
v v v v v v
3. Increase the length of time a drug is available and active
v v v v v v v v v v
4. Are most common in collagen tissues - Correct Answer - 3. Increase the length of time a drug is
v v v v v v v v v v v v v v v v v v
available and active
v v v
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
v v v v v v v v v v v v v v
1. Propensity to go to the target receptor v v v v v v
2. Biological half-life v
3. Pharmacodynamics
4. Safety and side effects - Correct Answer - 2. Biological half-life
v v v v v v v v v v
Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of the
v v v v v v v v v v v v v v v v v
prescription. This is considered a loading dose. A loading dose:
v v v v v v v v v v
1. Rapidly achieves drug levels in the therapeutic range
v v v v v v v
2. Requires four- to five-half-lives to attain v v v v v
3. Is influenced by renal function
v v v v
4. Is directly related to the drug circulating to the target tissues - Correct Answer - 1. Rapidly achieves
v v v v v v v v v v v v v v v v v
drug levels in the therapeutic range
v v v v v v
pg. 3
v
, The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the:
v v v v v v v v v v v v v v v v v v v
1. Minimum adverse effect level v v v
2. Peak of action v v
3. Onset of action v v
4. Therapeutic range - Correct Answer - 3. Onset of action v v v v v v v v v
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
v v v v v v v v v v v v v
1. When the drug has a wide therapeutic range
v v v v v v v
2. When the drug will be administered for a short time only
v v v v v v v v v v
3. When there is a high correlation between the dose and saturation of receptor sites
v v v v v v v v v v v v v
4. To determine if a drug is in the therapeutic range - Correct Answer - 4. To determine if a drug is in the
v v v v v v v v v v v v v v v v v v v v v v
therapeutic range
v v
A laboratory result indicates that the peak level for a drug is above the minimum toxic concentration. This
v v v v v v v v v v v v v v v v v
means that the:
v v v
1. Concentration will produce therapeutic effects v v v v
2. Concentration will produce an adverse response v v v v v
3. Time between doses must be shortened
v v v v v
4. Duration of action of the drug is too long - Correct Answer - 2. Concentration will produce an adverse
v v v v v v v v v v v v v v v v v v
response
v
Drugs that are receptor agonists may demonstrate what property?
v v v v v v v v
1. Irreversible binding to the drug receptor site v v v v v v
2. Upregulation with chronic use v v v
3. Desensitization or downregulation with continuous use v v v v v
4. Inverse relationship between drug concentration and drug action - Correct Answer - 3. Desensitization or
v v v v v v v v v v v v v v
downregulation with continuous use
v v v v
pg. 4v
v v v v v v v
Practical Approach 5th Edition By Virginia Poole Arcangelo,
v v v v v v v v
Andrew M Peterson, Veronica Wilbur, Tep M. Kang/ All
v v v v v v v v v
Chapters Covered – Latest Update 2024. v v v v v
Nurse practitioner prescriptive authority is regulated by:
v v v v v v
1. The National Council of State Boards of Nursing
v v v v v v v
2. The U.S. Drug Enforcement Administration
v v v v
3. The State Board of Nursing for each state
v v v v v v v
4. The State Board of Pharmacy - Correct Answer - 3. The State Board of Nursing for each state
v v v v v v v v v v v v v v v v v
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber include:
v v v v v v v v v v v v v v
1. Nurses know more about Pharmacology than other prescribers because they take it both in their basic
v v v v v v v v v v v v v v v
nursing program and in their APRN program.
v v v v v v v
2. Nurses care for the patient from a holistic approach and include the patient in decision making
v v v v v v v v v v v v v v v
regarding their care.
v v v
3. APRNs are less likely to prescribe narcotics and other controlled substances.
v v v v v v v v v v
4. APRNs are able to prescribe independently in all states, whereas a physician's assistant needs to have a
v v v v v v v v v v v v v v v v
physician supervising their practice. - Correct Answer - 2. Nurses care for the patient from a holistic
v v v v v v v v v v v v v v v v v
approach and include the patient in decision making regarding their care.
v v v v v v v v v v v
Clinical judgment in prescribing includes:
v v v v
1. Factoring in the cost to the patient of the medication prescribed
v v v v v v v v v v
2. Always prescribing the newest medication available for the disease process
v v v v v v v v v
3. Handing out drug samples to poor patients v v v v v v
4. Prescribing all generic medications to cut costs - Correct Answer - 1. Factoring in the cost to the
v v v v v v v v v v v v v v v v v
patient of the medication prescribed
v v v v v
pg. 1
v
,Criteria for choosing an effective drug for a disorder include:
v v v v v v v v v
1. Asking the patient what drug they think would work best for them
v v v v v v v v v v v
2. Consulting nationally recognized guidelines for disease managementv v v v v v
3. Prescribing medications that are available as samples before writing a prescription
v v v v v v v v v v
4. Following U.S. Drug Enforcement Administration guidelines for prescribing - Correct Answer - 2.
v v v v v v v v v v v v
Consulting nationally recognized guidelines for disease management
v v v v v v v
Nurse practitioner practice may thrive under health-care reform because of:
v v v v v v v v v
1. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes
v v v v v v v v v v v v
2. The fact that nurse practitioners will be able to practice independently
v v v v v v v v v v
3. The fact that nurse practitioners will have full reimbursement under health-care reform
v v v v v v v v v v v
4. The ability to shift accountability for Medicaid to the state level - Correct Answer - 1. The
v v v v v v v v v v v v v v v v
demonstrated ability of nurse practitioners to control costs and improve patient outcomes
v v v v v v v v v v v v
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This is
v v v v v v v v v v
critical to prescribing because:
v v v v
1. Distribution of drugs to target tissue may be affected. v v v v v v v v
2. The solubility of the drug will not match the site of absorption.
v v v v v v v v v v v
3. There will be less free drug available to generate an effect.
v v v v v v v v v v
4. Drugs bound to albumin are readily excreted by the kidneys. - Correct Answer - 1. Distribution of drugs to
v v v v v v v v v v v v v v v v v v
target tissue may be affected.
v v v v v
Drugs that have a significant first-pass effect:
v v v v v v
1. Must be given by the enteral (oral) route only
v v v v v v v v
2. Bypass the hepatic circulation v v v
3. Are rapidly metabolized by the liver and may have little if any desired action
v v v v v v v v v v v v v
pg. 2v
,4. Are converted by the liver to more active and fat-soluble forms - Correct Answer - 3. Are rapidly
v v v v v v v v v v v v v v v v v
metabolized by the liver and may have little if any desired action
v v v v v v v v v v v v
The route of excretion of a volatile drug will likely be the:
v v v v v v v v v v v
1. Kidneys
2. Lungs
3. Bile and feces v v
4. Skin - Correct Answer - 2. Lungs
v v v v v v
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir of v v v v v v v v v v v v
the drug. Storage reservoirs:
v v v v
1. Assure that the drug will reach its intended target tissue
v v v v v v v v v
2. Are the reason for giving loading doses
v v v v v v
3. Increase the length of time a drug is available and active
v v v v v v v v v v
4. Are most common in collagen tissues - Correct Answer - 3. Increase the length of time a drug is
v v v v v v v v v v v v v v v v v v
available and active
v v v
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
v v v v v v v v v v v v v v
1. Propensity to go to the target receptor v v v v v v
2. Biological half-life v
3. Pharmacodynamics
4. Safety and side effects - Correct Answer - 2. Biological half-life
v v v v v v v v v v
Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of the
v v v v v v v v v v v v v v v v v
prescription. This is considered a loading dose. A loading dose:
v v v v v v v v v v
1. Rapidly achieves drug levels in the therapeutic range
v v v v v v v
2. Requires four- to five-half-lives to attain v v v v v
3. Is influenced by renal function
v v v v
4. Is directly related to the drug circulating to the target tissues - Correct Answer - 1. Rapidly achieves
v v v v v v v v v v v v v v v v v
drug levels in the therapeutic range
v v v v v v
pg. 3
v
, The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the:
v v v v v v v v v v v v v v v v v v v
1. Minimum adverse effect level v v v
2. Peak of action v v
3. Onset of action v v
4. Therapeutic range - Correct Answer - 3. Onset of action v v v v v v v v v
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
v v v v v v v v v v v v v
1. When the drug has a wide therapeutic range
v v v v v v v
2. When the drug will be administered for a short time only
v v v v v v v v v v
3. When there is a high correlation between the dose and saturation of receptor sites
v v v v v v v v v v v v v
4. To determine if a drug is in the therapeutic range - Correct Answer - 4. To determine if a drug is in the
v v v v v v v v v v v v v v v v v v v v v v
therapeutic range
v v
A laboratory result indicates that the peak level for a drug is above the minimum toxic concentration. This
v v v v v v v v v v v v v v v v v
means that the:
v v v
1. Concentration will produce therapeutic effects v v v v
2. Concentration will produce an adverse response v v v v v
3. Time between doses must be shortened
v v v v v
4. Duration of action of the drug is too long - Correct Answer - 2. Concentration will produce an adverse
v v v v v v v v v v v v v v v v v v
response
v
Drugs that are receptor agonists may demonstrate what property?
v v v v v v v v
1. Irreversible binding to the drug receptor site v v v v v v
2. Upregulation with chronic use v v v
3. Desensitization or downregulation with continuous use v v v v v
4. Inverse relationship between drug concentration and drug action - Correct Answer - 3. Desensitization or
v v v v v v v v v v v v v v
downregulation with continuous use
v v v v
pg. 4v
