NR 568 ADVANCED PHARMACOLOGY WEEK 6 QUESTIONS AND
ANSWERS COMPLETE CHAMBERLAIN COLLEGE.
1. How do you manage Parkin- Either with Pramipexole (mirapex) OR Rotig-
sons disease in early stages otine (Neupro)
2. What is the most effective Combination therapy with levodopa/car-
therapy for PD bidopa or levodopa/carbidopa/entacapone
3. What medications are used Dopamine agonists, COMT inhibitors and
to treat off times including MAO-B inhibitors.
wearing off experiences
Entacapone-COMT- inhibitor
Rasagiline- MAO- B inhibitor
4. Adverse effects of Pramipex- Nausea, dizziness, daytime somnolence, in-
ole somnia, constipation, weakness, and halluci-
nations, impulse control disorders
5. Which medication is the Pregabalin
safest choice for someone
on oral contraceptive
6. What is the purpose and tim- small changes in dosage produce large
ing of serum drug levels changes in plasma levels, as a result small
increases in dosage can cause toxicity and
small decreases can cause therapeutic fail-
ure. this relationship makes it difficult to es-
tablish and maintain a dosage that is both
safe and effective. for this reason, serum drug
levels and trough levels are often used along
with assessments of seizure control o deter-
mine dosage.
7. Phenytoin drug interactions Oxcarbazepine inhibits the enzymes that
metabolize phenytoin thus raising pheny-
toin. Controversially phenytoin may decrease
serum concentrations of oxcarbazepine
8. What can happen when you bazepine together
take phenytoin and oxcar-
, NR 568 ADVANCED PHARMACOLOGY WEEK 6 QUESTIONS AND
ANSWERS COMPLETE CHAMBERLAIN COLLEGE.
phenytoin toxicity and
subtherapeutic levelsof
oxcarbazepine can occur.
These levels
ANSWERS COMPLETE CHAMBERLAIN COLLEGE.
1. How do you manage Parkin- Either with Pramipexole (mirapex) OR Rotig-
sons disease in early stages otine (Neupro)
2. What is the most effective Combination therapy with levodopa/car-
therapy for PD bidopa or levodopa/carbidopa/entacapone
3. What medications are used Dopamine agonists, COMT inhibitors and
to treat off times including MAO-B inhibitors.
wearing off experiences
Entacapone-COMT- inhibitor
Rasagiline- MAO- B inhibitor
4. Adverse effects of Pramipex- Nausea, dizziness, daytime somnolence, in-
ole somnia, constipation, weakness, and halluci-
nations, impulse control disorders
5. Which medication is the Pregabalin
safest choice for someone
on oral contraceptive
6. What is the purpose and tim- small changes in dosage produce large
ing of serum drug levels changes in plasma levels, as a result small
increases in dosage can cause toxicity and
small decreases can cause therapeutic fail-
ure. this relationship makes it difficult to es-
tablish and maintain a dosage that is both
safe and effective. for this reason, serum drug
levels and trough levels are often used along
with assessments of seizure control o deter-
mine dosage.
7. Phenytoin drug interactions Oxcarbazepine inhibits the enzymes that
metabolize phenytoin thus raising pheny-
toin. Controversially phenytoin may decrease
serum concentrations of oxcarbazepine
8. What can happen when you bazepine together
take phenytoin and oxcar-
, NR 568 ADVANCED PHARMACOLOGY WEEK 6 QUESTIONS AND
ANSWERS COMPLETE CHAMBERLAIN COLLEGE.
phenytoin toxicity and
subtherapeutic levelsof
oxcarbazepine can occur.
These levels
