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Samenvatting Histologie - Kraakbeen

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Samenvatting van H3 Kraakbeen uit boek Cytologie en histologie. Notities en extra info uit de les zijn hierin verwerkt. 1e bach revaki Ugent

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Summarized whole book?
No
Which chapters are summarized?
H3 histologie
Uploaded on
February 7, 2020
Number of pages
6
Written in
2019/2020
Type
Summary

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Kraakbeen
 Steunweefsel
 Plooibaar (veel water), niet broos
 Geen bloedvaten, zenuwen of lymfevaten
 Lacune = kleine holte in grondstof

Soorten

 Hyalien kraakbeen
o Bv kraakbeen neus
o Chondrocyten (oud, meest mature)
- Ronde cellen
- Grote centrale kern met veel nucleoli
- Produceren collageen (eiwitten)
- Veel uitstulpingen
- Veel ribosomen, RER, goede Golgi, veel mitoc
- Chondronen = groepering van chondrocyten


o Of Chondroblast (jong), minder actief
- Elliptische cellen
- Geen chondronen


o Extracellulair materiaal
- Vezels: rechte structuren, netwerk; collageen II
- Grondsubstantie
Proteoglycanen (chondroïtinesulfaat/keratansulfaat)
Vormen aggregaten met hyaluronzuur

o Perichondrium = periferie
- Omgeeft hyalien kraakbeen
- Dichte laag bindweefsel
- Via diffusie
- Fibroblasten (stamcellen) en kraakbeencellen
- Hierin liggen blodvaten, zenuwen en lymfevaten

o Voeding: diffusie
- Chondrocyten: glycolytisch metabolisme
Wijst op: glycolyse; is dominant bij anaeroob
Diffusiecap is traag; O2 levering is traag

o Regeneratie: traag, vanuit perichondriu

,  Elastisch kraakbeen
o Chondrocyten en chondroblasten (& chondronen, zie hierboven)
o Extracellulair materiaal
- Bevat veel meer elastine (netwerk)
- Ook collageenvezels
- Grondsubstantie: meer weefselvloeistof voor soepelheid

o Perichondrium
o Regenereert traag




 Fibrocartilago
o In tussenwervelschijven
o Regenereert zeer traag
o Vangt sterke druk-torsiekrachten op
o Cellen:
- Chondrocyten: in korte rijen achter elkaar
- Chondronen: overwegend tweecellig

o Extracellulair materiaal
- Collageenvezels: dikke bundels (weinig grondstof)
- Alternerende lagen grondstof hyalien
kraakbeen met chondrocyten en dikke lagen
collagene vezels
- Weerstandig!
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