Bioinformatics and Genomics Chapter 18 Exam Questions and Correct Answers Already Passed
structural genomics - Answers sequencing genomes and identifying genes and regulatory regions
whole genome shotgun sequencing - Answers entire genome broken into small frangments of DNA
contiguous fragments - Answers overlapping fragments of a cut chromosome
DNA sequence alignment - Answers similar contigs are aligned for analysis and comparison
Computer -Automated DNA sequencing - Answers organized sequencing of nucleotides by a computer
high throughput sequencing - Answers can process millions of base pairs in a day
bioinformatics - Answers the use of computers and math apps to organize and anlyze genes
annotation - Answers identifying gen regulatory sequences in the genome (the important stuff)
BLAST - Answers basic local alignment search: used to compare new segments with existing ones
similarity score - Answers determined by the sum of identical matches/bases aligned
open reading frame - Answers sequence of nucleotides that are translated into amino acids
ORF recognition - Answers initiation sequences (AUG), termination sequences (UAA, UGA, UAG)
polyadenylation sequences
functional genomics - Answers study of gene functions
homologous genes - Answers evolutionary related genes
Leptin - Answers gene that produces the protein hormone leptin which suppresses appetite (fat mice)
ortholog - Answers homolgous genes in different species dervived from a common ancestor
paralog - Answers homologous genes in same species (human aglobin and b globin subunits)
Domain vs Motif - Answers motifs are patterns found in a protein and domains are functional regions
made of motifs
Domain example: - Answers ion channels
motif - Answers leucine zipper, zinc-finger
ELSI - Answers Program made to protect rights of people and their genetic information
Dr. J Craig Venter - Answers developed whole genome shotgun sequencing
Francis Collins and James Watson - Answers human genome project
structural genomics - Answers sequencing genomes and identifying genes and regulatory regions
whole genome shotgun sequencing - Answers entire genome broken into small frangments of DNA
contiguous fragments - Answers overlapping fragments of a cut chromosome
DNA sequence alignment - Answers similar contigs are aligned for analysis and comparison
Computer -Automated DNA sequencing - Answers organized sequencing of nucleotides by a computer
high throughput sequencing - Answers can process millions of base pairs in a day
bioinformatics - Answers the use of computers and math apps to organize and anlyze genes
annotation - Answers identifying gen regulatory sequences in the genome (the important stuff)
BLAST - Answers basic local alignment search: used to compare new segments with existing ones
similarity score - Answers determined by the sum of identical matches/bases aligned
open reading frame - Answers sequence of nucleotides that are translated into amino acids
ORF recognition - Answers initiation sequences (AUG), termination sequences (UAA, UGA, UAG)
polyadenylation sequences
functional genomics - Answers study of gene functions
homologous genes - Answers evolutionary related genes
Leptin - Answers gene that produces the protein hormone leptin which suppresses appetite (fat mice)
ortholog - Answers homolgous genes in different species dervived from a common ancestor
paralog - Answers homologous genes in same species (human aglobin and b globin subunits)
Domain vs Motif - Answers motifs are patterns found in a protein and domains are functional regions
made of motifs
Domain example: - Answers ion channels
motif - Answers leucine zipper, zinc-finger
ELSI - Answers Program made to protect rights of people and their genetic information
Dr. J Craig Venter - Answers developed whole genome shotgun sequencing
Francis Collins and James Watson - Answers human genome project
