The light-colored zone adjacent to the nucleus in a plasmacyte is the:
A. Ribosome
B. Chromatin
C. Mitochondria
D. Golgi area - ✔✔Correct Answer: D
The following are compounds formed in the synthesis of heme:
1. coproporphyrinogen
2. porphobilinogen
3. uroporphyrinogen
4. protoporphyrinogen
A. 4,3,1,2
B. 2,3,1,4
C. 4,2,3,1
D. 2,1,3,4 - ✔✔Correct Answer: B
The majority of the iron in an adult is found as a constituent of:
A. hemoglobin
B. hemosiderin
C. myoglobin
D. transferrin - ✔✔Correct Answer: A
The main function of the hexose monophosphate shunt in the erythrocyte is to:
A. regulate the level of 2,3-DPG
B. provide reduced glutathione to prevent oxidation of hemoglobin
C. prevent the reduction of heme iron
D. provide energy for membrane maintenance - ✔✔Correct Answer: B
,Correct Answer: B - ✔✔Refer to the following illustration:
Which curve represents the production of alpha polypeptide chains of hemoglobin?
A. A
B. B
C. C
D. D
Correct Answer: D - ✔✔Refer to the following illustration:
Which curve represents the production of beta polypeptide chains of hemoglobin?
A. B
B. C
C. E
D. D
Correct Answer: C - ✔✔Refer to the following illustration:
Which curve represents the production of gamma polypeptide chains of hemoglobin?
A. A
B. B
C. C
D. D
Correct Answer: D - ✔✔Refer to the following illustration:
,Which curve represents the production of delta polypeptide chains of hemoglobin?
A. B
B. C
C. D
D. E
Correct Answer: A - ✔✔Refer to the following illustration:
Which curve represents the production of epsilon polypeptide chains of hemoglobin?
A. A
B. B
C. C
D. D
In order for hemoglobin to combine reversibly with oxygen, the iron must be:
A. complexed with haptoglobin
B. freely circulating in the cytoplasm
C. attached to transferrin
D. in the ferrous state - ✔✔Correct Answer: D
In which of the following disease states are teardrop cells and abnormal platelets most
characteristically seen?
A. hemolytic anemia
B. multiple myeloma
C. G-6-PD deficiency
D. myeloid metaplasia - ✔✔Correct Answer: D
, The characteristic erythrocyte found in pernicious anemia is:
A. microcytic
B. spherocytic
C. hypochromic
D. macrocytic - ✔✔Correct Answer: D
In the normal adult, the spleen acts as a site for:
A. storage of red blood cells
B. production of red blood cells
C. synthesis of erythropoietin
D. removal of imperfect and aging cells - ✔✔Correct Answer: D
After the removal of red blood cells from the circulation hemoglobin is broken down into:
A. iron, porphyrin, and amino acids
B. iron, protoporphyrin, and globin
C. heme, protoporphyrin, and amino acids
D. heme, hemosiderin, and globin - ✔✔Correct Answer: B
Heinz bodies are:
A. readily identified with polychrome stains
B. rarely found in glucose-6-phosphate dehydrogenase deficient erythrocytes
C. closely associated with spherocytes
D. denatured hemoglobin inclusions that are readily removed by the spleen - ✔✔Correct
Answer: D
Hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) is:
A. temperature-dependent
B. complement-independent
C. antibody-mediated