, lOMoARcPSD| 47481126
Week 5
- Prevention of osteoporosis with hormone replacement therapy
- When and when not to use progestin for hormone replacement
therapy and why
- Local vs. systemic estrogen options and why one would be
chosen over the other o Peri-menopausal estrogen therapy (ET)
- Transdermal estrogen therapy has fewer adverse effects.
- Osteoporosis, osteopenia, and hormone replacement therapy
(HRT) o Selective estrogen receptor modulator (SERM)
Bazedoxifene
- Management of oral contraceptives (OCs) o How to change
patient from one combination oral contraceptive to another.
o How to initiate treatment (when in the cycle is it best to start-
may vary based on the type of contraceptive)
o What teaching needs to be done o What baseline data is
needed?
o Contraindications for OCs
- How to achieve an extended cycle with oral contraceptives
- What behaviors would make one birth control method more
effective over another?
o Be able to evaluate a patient scenario and suggest an
appropriate birth control method (type of prescribed
contraception: OC, long-term methods, IUD, longacting
reversible contraceptives (LARCs), etc.
- What effect does CYP450 inhibitors or inducers have on OCs?
o Recall examples of CYP450 inhibitors and inducers from NR565
(Chapter 4 in textbook)
o How does this impact prescribing of OCs? - Benefits and
drawbacks of progestin-only contraception - What are the
most effective forms of contraception?
- Testosterone replacement o Administration o Benefits o Patient
Teaching
1
, lOMoARcPSD| 47481126
- Treatment of delayed puberty o When is it appropriate to initiate
androgen therapy (short course and long-term)
- Androgen therapy o Effects
Therapeutic
Adverse o Monitoring Needs
o Role of androgens in treating anemia
- Preferred administration route of alprostadil and why
- Treatment of hypogonadism o Benefits
o Administration methods for transdermal preparations
Testosterone gels
- Erectile Dysfunction (ED) o Patient Teaching
o Medication Classes used to treat ED
Vasodilators
PGE1
- Treatment of BPH o Know examples of drugs in each major drug
class
o Adverse effects of common therapies
5-α-Reductase Inhibitors:
α1 Blockers principal adverse effects are hypotension,
fainting, dizziness, somnolence, and nasal congestion.
However, silodosin and tamsulosin can cause abnormal
ejaculation (ejaculation failure,
2
Week 5
- Prevention of osteoporosis with hormone replacement therapy
- When and when not to use progestin for hormone replacement
therapy and why
- Local vs. systemic estrogen options and why one would be
chosen over the other o Peri-menopausal estrogen therapy (ET)
- Transdermal estrogen therapy has fewer adverse effects.
- Osteoporosis, osteopenia, and hormone replacement therapy
(HRT) o Selective estrogen receptor modulator (SERM)
Bazedoxifene
- Management of oral contraceptives (OCs) o How to change
patient from one combination oral contraceptive to another.
o How to initiate treatment (when in the cycle is it best to start-
may vary based on the type of contraceptive)
o What teaching needs to be done o What baseline data is
needed?
o Contraindications for OCs
- How to achieve an extended cycle with oral contraceptives
- What behaviors would make one birth control method more
effective over another?
o Be able to evaluate a patient scenario and suggest an
appropriate birth control method (type of prescribed
contraception: OC, long-term methods, IUD, longacting
reversible contraceptives (LARCs), etc.
- What effect does CYP450 inhibitors or inducers have on OCs?
o Recall examples of CYP450 inhibitors and inducers from NR565
(Chapter 4 in textbook)
o How does this impact prescribing of OCs? - Benefits and
drawbacks of progestin-only contraception - What are the
most effective forms of contraception?
- Testosterone replacement o Administration o Benefits o Patient
Teaching
1
, lOMoARcPSD| 47481126
- Treatment of delayed puberty o When is it appropriate to initiate
androgen therapy (short course and long-term)
- Androgen therapy o Effects
Therapeutic
Adverse o Monitoring Needs
o Role of androgens in treating anemia
- Preferred administration route of alprostadil and why
- Treatment of hypogonadism o Benefits
o Administration methods for transdermal preparations
Testosterone gels
- Erectile Dysfunction (ED) o Patient Teaching
o Medication Classes used to treat ED
Vasodilators
PGE1
- Treatment of BPH o Know examples of drugs in each major drug
class
o Adverse effects of common therapies
5-α-Reductase Inhibitors:
α1 Blockers principal adverse effects are hypotension,
fainting, dizziness, somnolence, and nasal congestion.
However, silodosin and tamsulosin can cause abnormal
ejaculation (ejaculation failure,
2
