SNL Reaction
substitution nucleophilic bimolecular
onestep 2 molecules
LG nu
Fr LG
Nu
T
backside attacksgivesinversion in chirality
rate K alkyl CNUT
2nd order
good LG SN E
i'Br L 0 z CN 0
DMSO
iii i
2ohm I polaraprotic co
l w2
leaving group capableof being
kickedout
Ex
2 charged strongenough
13
A acetoneSN
so I r n
futz
lpolaraprotic
good LG
1 and 2 H'son C
S is a weakbase bc it'slarge Atom is polarizable
betternucleophile
Ex c c cites
c 0
to
DMSO
If
rl polaraprotic
notchiral
Alkylchain to
leavinggroup decent
substitution nucleophilic bimolecular
onestep 2 molecules
LG nu
Fr LG
Nu
T
backside attacksgivesinversion in chirality
rate K alkyl CNUT
2nd order
good LG SN E
i'Br L 0 z CN 0
DMSO
iii i
2ohm I polaraprotic co
l w2
leaving group capableof being
kickedout
Ex
2 charged strongenough
13
A acetoneSN
so I r n
futz
lpolaraprotic
good LG
1 and 2 H'son C
S is a weakbase bc it'slarge Atom is polarizable
betternucleophile
Ex c c cites
c 0
to
DMSO
If
rl polaraprotic
notchiral
Alkylchain to
leavinggroup decent