NUR4271 Conditions of Cortisol (Cushings & Addison's
disease) + diabetes Exam
Cortisol, adrenal cortex - ANSWER Cushing's Disease (hypercortisolism) is a condition
of an excess of the hormone ____ in the blood from the ____ ______
secondary Cushing's syndrome. - ANSWER Cushing' s disease is also called _____
adrenal cortex, anterior pituitary gland, or hypothalamus - ANSWER Problems w/
hypercortisolism (Cushings) can be due to problems with the _____,_____, or _____
long term, high dose, glucocorticoid therapy (ex: prednisone) - ANSWER Cushing's
SYNDROME is most commonly caused by ________
Adrenal gland malignancy - ANSWER Primary (endogenous) hypercortisolism is caused
by _________
•Excessive secretion of Adrenocorticotropic hormone (ACTH), by a pituitary tumor
•Ectopic- caused by another malignancy (e.g., lung cancer) (extra-pituitary) - ANSWER
Secondary (Cushing's DISEASE) (endogenous) hypercortisolism is caused by _______
long term corticosteroid therapy (asthma, COPD) - ANSWER Cushing's syndrome
(exogenous) is most commonly caused by ________
C. one month
•Symptoms associated with exogenous Cushing syndrome typically do not develop until
the client is on corticosteroids for at least one month. - ANSWER How long does a client
need to be on glucocorticoid therapy to be at risk for Cushing's syndrome?
, •A. one day
•B. one week
•C. one month
•D. one year
- full blown moon-face
-growing gut
-memory was shot
-aching all over
-three hours of sleep
-feeling lost, hopeless, scared (emotional disturbances) - ANSWER which symptoms are
supportive of Cushing's syndrome:
•By June 2016, I had full-blown moon-face, and my gut was somehow still growing. I
didn't fit into any of my clothes. My memory was shot. I was aching all over. And I was
lucky to get three hours of sleep each night. At this point, I was feeling lost, hopeless,
and scared.
•Visceral fat deposits- slow turnover of fatty acids
•Decreased muscle mass- breakdown of tissue protein
•Fat deposit different than obesity
•Fat deposits on face, clavicular area
•Extremities remain thin
•Acne - ANSWER Early signs & symptoms of Cushing's?
•Moon face
•Purple striae on chest, armpits, abdomen
•Hypertension
•Skin ulcers
disease) + diabetes Exam
Cortisol, adrenal cortex - ANSWER Cushing's Disease (hypercortisolism) is a condition
of an excess of the hormone ____ in the blood from the ____ ______
secondary Cushing's syndrome. - ANSWER Cushing' s disease is also called _____
adrenal cortex, anterior pituitary gland, or hypothalamus - ANSWER Problems w/
hypercortisolism (Cushings) can be due to problems with the _____,_____, or _____
long term, high dose, glucocorticoid therapy (ex: prednisone) - ANSWER Cushing's
SYNDROME is most commonly caused by ________
Adrenal gland malignancy - ANSWER Primary (endogenous) hypercortisolism is caused
by _________
•Excessive secretion of Adrenocorticotropic hormone (ACTH), by a pituitary tumor
•Ectopic- caused by another malignancy (e.g., lung cancer) (extra-pituitary) - ANSWER
Secondary (Cushing's DISEASE) (endogenous) hypercortisolism is caused by _______
long term corticosteroid therapy (asthma, COPD) - ANSWER Cushing's syndrome
(exogenous) is most commonly caused by ________
C. one month
•Symptoms associated with exogenous Cushing syndrome typically do not develop until
the client is on corticosteroids for at least one month. - ANSWER How long does a client
need to be on glucocorticoid therapy to be at risk for Cushing's syndrome?
, •A. one day
•B. one week
•C. one month
•D. one year
- full blown moon-face
-growing gut
-memory was shot
-aching all over
-three hours of sleep
-feeling lost, hopeless, scared (emotional disturbances) - ANSWER which symptoms are
supportive of Cushing's syndrome:
•By June 2016, I had full-blown moon-face, and my gut was somehow still growing. I
didn't fit into any of my clothes. My memory was shot. I was aching all over. And I was
lucky to get three hours of sleep each night. At this point, I was feeling lost, hopeless,
and scared.
•Visceral fat deposits- slow turnover of fatty acids
•Decreased muscle mass- breakdown of tissue protein
•Fat deposit different than obesity
•Fat deposits on face, clavicular area
•Extremities remain thin
•Acne - ANSWER Early signs & symptoms of Cushing's?
•Moon face
•Purple striae on chest, armpits, abdomen
•Hypertension
•Skin ulcers
