NR565 Advanced Pharmacology Midterm
Exam UPDATED ACTUAL Exam
Questions and CORRECT Answers
Schedule 3-5 drugs - CORRECT ANSWER✔✔- Drugs that APRNs can prescribe
Prescriptive authority regulation - CORRECT ANSWER✔✔- Determined by State Boards of
Nursing, Medicine, and Pharmacy
Limited prescriptive authority impact - CORRECT ANSWER✔✔- Leads to fewer treatment
options for patients, requiring them to find providers with authority
Key responsibilities of prescribing - CORRECT ANSWER✔✔- Understanding prescribed
drugs, their effects, contraindications, and ensuring correct dosages
BSCRAP GPS Incudes Rage - CORRECT ANSWER✔✔- Acronym for CYP450 enzyme
inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin, Alcohol, Phenytoin,
Griseofulvin, Phenobarbital, Sulfonylureas
Bioavailability - CORRECT ANSWER✔✔- Amount of active drug reaching systemic
circulation from administration site
Reasons for medication nonadherence - CORRECT ANSWER✔✔- Include forgetfulness,
lack of planning, cost, dissatisfaction, and altered dosing
IM administration in neonates and infants - CORRECT ANSWER✔✔- Absorption is slow in
neonates due to low muscle blood flow; absorption becomes rapid in early infancy
Oral administration in neonates/infants - CORRECT ANSWER✔✔- Gastric emptying time is
prolonged and irregular in early infancy, affecting drug absorption
Dosage determination for pediatric patients - CORRECT ANSWER✔✔- Based on body
surface area (BSA) calculation
, Guiding principles for prescribers - CORRECT ANSWER✔✔- Steps include defining the
problem, setting therapeutic objectives, choosing treatment, verifying its suitability, starting
treatment, giving information, and monitoring treatment
CYP450 inhibitors - CORRECT ANSWER✔✔- Examples include Valproate, Isoniazid,
Sulfonamides, Amiodarone, Chloramphenicol, Ketoconazole, Grapefruit juice, Quinidine
Pharmacokinetics and pharmacodynamics - CORRECT ANSWER✔✔- Basis for prescribing
decisions, considering drug interactions and effects on target receptors
Beer's Criteria - CORRECT ANSWER✔✔- Tool identifying inappropriate medication use in
older adults, cautioning against certain drugs and interactions
Impacts of polypharmacy - CORRECT ANSWER✔✔- Include adverse drug events,
increased healthcare interactions, cognitive impairment, reduced adherence, falls, and
mortality
CYP450 inhibitors function - CORRECT ANSWER✔✔- They decrease medication
metabolism
CYP450 inhibitors consequences - CORRECT ANSWER✔✔- May cause toxicity if enzymes
are inactive or ineffectiveness if enzymes are overactive
Poor metabolism phenotype - CORRECT ANSWER✔✔- Occurs when CYP2D6 alleles have
inactivating mutations, leading to enzyme synthesis with impaired or no activity
US FDA regulation - CORRECT ANSWER✔✔- Ensures safety, efficiency, and security of
human and veterinary drugs, biological products, and medical devices
Pure Opioid Agonists - CORRECT ANSWER✔✔- Include heroin, oxycodone, methadone,
and morphine.
Exam UPDATED ACTUAL Exam
Questions and CORRECT Answers
Schedule 3-5 drugs - CORRECT ANSWER✔✔- Drugs that APRNs can prescribe
Prescriptive authority regulation - CORRECT ANSWER✔✔- Determined by State Boards of
Nursing, Medicine, and Pharmacy
Limited prescriptive authority impact - CORRECT ANSWER✔✔- Leads to fewer treatment
options for patients, requiring them to find providers with authority
Key responsibilities of prescribing - CORRECT ANSWER✔✔- Understanding prescribed
drugs, their effects, contraindications, and ensuring correct dosages
BSCRAP GPS Incudes Rage - CORRECT ANSWER✔✔- Acronym for CYP450 enzyme
inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin, Alcohol, Phenytoin,
Griseofulvin, Phenobarbital, Sulfonylureas
Bioavailability - CORRECT ANSWER✔✔- Amount of active drug reaching systemic
circulation from administration site
Reasons for medication nonadherence - CORRECT ANSWER✔✔- Include forgetfulness,
lack of planning, cost, dissatisfaction, and altered dosing
IM administration in neonates and infants - CORRECT ANSWER✔✔- Absorption is slow in
neonates due to low muscle blood flow; absorption becomes rapid in early infancy
Oral administration in neonates/infants - CORRECT ANSWER✔✔- Gastric emptying time is
prolonged and irregular in early infancy, affecting drug absorption
Dosage determination for pediatric patients - CORRECT ANSWER✔✔- Based on body
surface area (BSA) calculation
, Guiding principles for prescribers - CORRECT ANSWER✔✔- Steps include defining the
problem, setting therapeutic objectives, choosing treatment, verifying its suitability, starting
treatment, giving information, and monitoring treatment
CYP450 inhibitors - CORRECT ANSWER✔✔- Examples include Valproate, Isoniazid,
Sulfonamides, Amiodarone, Chloramphenicol, Ketoconazole, Grapefruit juice, Quinidine
Pharmacokinetics and pharmacodynamics - CORRECT ANSWER✔✔- Basis for prescribing
decisions, considering drug interactions and effects on target receptors
Beer's Criteria - CORRECT ANSWER✔✔- Tool identifying inappropriate medication use in
older adults, cautioning against certain drugs and interactions
Impacts of polypharmacy - CORRECT ANSWER✔✔- Include adverse drug events,
increased healthcare interactions, cognitive impairment, reduced adherence, falls, and
mortality
CYP450 inhibitors function - CORRECT ANSWER✔✔- They decrease medication
metabolism
CYP450 inhibitors consequences - CORRECT ANSWER✔✔- May cause toxicity if enzymes
are inactive or ineffectiveness if enzymes are overactive
Poor metabolism phenotype - CORRECT ANSWER✔✔- Occurs when CYP2D6 alleles have
inactivating mutations, leading to enzyme synthesis with impaired or no activity
US FDA regulation - CORRECT ANSWER✔✔- Ensures safety, efficiency, and security of
human and veterinary drugs, biological products, and medical devices
Pure Opioid Agonists - CORRECT ANSWER✔✔- Include heroin, oxycodone, methadone,
and morphine.
