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Summary Learning goals case 10

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January 24, 2020
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Learninggoals case 10
1. What diseases are caused by a sedentary lifestyle?
Risk factors sedentary lifestyle:
- Physical inactivity may increase the risks of certain cancers.
- Physical inactivity may contribute to anxiety and depression.
- Physical inactivity has been shown to be a risk factor for certain cardiovascular
diseases.
- People who engage in more physical activity are less likely to develop coronary heart
disease.
- People who are more active are less likely to be overweight or obese.
- Sitting too much may cause a decrease in skeletal muscle mass.
- Physical inactivity is linked to high blood pressure and elevated cholesterol levels.

Risk factors coronary heart disease (CHD)
Cannot be controlled
- Heredity
- Race
- Male sex
- Advanced age
Primary risk factors that can be controlled
- Tobacco smoke
- Hypertension
- Abnormal blood lipids and lipoproteins
 High levels of low-density lipoprotein cholesterol (LDL-C)
Responsible for depositing cholesterol in the arterial wall
 Low levels of high-density lipoprotein cholesterol (HDL-C)
Scavenger that removes cholesterol from the arterial wall and transports it
to the liver to be metabolized
 Place a person at extremely high risk of having a heart attack at young age
under 60.
 Very low density lipoprotein cholesterol (VLDL-C) is becoming increasingly
implicated as a risk factor
 Only looking at cholesterol levels is not enough, it is the combination with
the levels LDL and HDL which determines someone’s risk.
The ratio of total cholesterol to HDL-C may be the best blood lipid index of
risk for CHD. Values of 3.0 or less place a person at low risk, but values of 5.0
or greater place a person at high risk.

- Physical inactivity
- Obesity and overweight
- Diabetes and insulin resistance

, Risk factors hypertension
Systolic pressure above 140 mmHg or diastolic 90 mmHg
Cannot be controlled
- Heredity
Plays a much smaller role than many of the other factors, lifestyle factors are often
quite similar within a family.
- Sex
- Advanced age
- Race (increased risk for people of African or Hispanic ancestry)
Primary risk factors that can be controlled
- Insulin resistance
- Obesity and overweight
- Diet (sodium and alcohol)
- Use of tobacco products
- Use of oral contraceptives (anticonceptie in de vorm van de pil)
- Stress
- Physical inactivity

Stroke
Two types of strokes (hemorrhagis)

Heart failure
- Systolic failure  heart does not pump heart enough, lower ejection fraction
- Diastolic failure  heart does not relax enough

Excessive weight and obesity and health problems:
- Coronary heart disease
- Hypertension
- Stroke
- Type 2 diabetes
- Certain types of cancer - endometrial, breast, and colon
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