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Test Bank For Mosby-s Pharmacology in Nursing , 22nd Edition All Chapters Covered.

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Chapter 3: Principles of Drug Action 1. A nurse is teaching a patient about the mechanism of action of a drug. Which statement by the patient indicates a need for further teaching? A) "The drug will bind to receptors and produce a response." B) "This drug will enhance the activity of an enzyme in my body." C) "The drug will work immediately after I take it." D) "The drug may block the effects of other substances in my body." Answer: C Rationale: Many drugs do not work immediately; there can be a time lag due to absorption and distribution processes. NCLEX Preference: Knowledge of pharmacodynamics. 2. The nurse understands that pharmacodynamics refers to: A) The study of how the body affects a drug. B) The study of how drugs affect the body. C) The process of drug absorption in the body. D) The elimination of drugs from the body. Answer: B Rationale: Pharmacodynamics is concerned with the effects of drugs on biological systems. NCLEX Preference: Understanding drug actions. 3. When assessing a patient’s response to a newly prescribed medication, the nurse recognizes that therapeutic effects are generally expected to occur within: A) Minutes B) Hours C) Days D) Weeks Answer: B Rationale: Many medications typically begin to exert therapeutic effects within hours. NCLEX Preference: Monitoring drug effects. 4. The nurse is administering a medication that works as an antagonist. What is the expected outcome of this type of drug? A) It will stimulate a physiological response. B) It will block the effect of a naturally occurring substance. C) It will have no effect on the receptor. D) It will enhance the binding of another drug. Answer: B Rationale: Antagonists bind to receptors but do not activate them, blocking the effects of agonists. NCLEX Preference: Understanding drug mechanisms. 5. Which of the following factors can significantly influence drug absorption? A) Patient’s age B) Route of administration C) Time of day D) All of the above Answer: D Rationale: Each factor can affect how quickly and effectively a drug is absorbed. NCLEX Preference: Factors affecting drug absorption. 6. A nurse is assessing a patient who has just started on a new medication. Which of the following would be an appropriate evaluation of the drug's efficacy? A) Checking the patient's vital signs. B) Asking the patient if they feel better after one dose. C) Monitoring the patient's lab values relevant to the condition. D) Reviewing the patient's medication history. Answer: C Rationale: Lab values provide objective evidence of drug efficacy over time. NCLEX Preference: Evaluating therapeutic outcomes. 7. Which of the following statements about drug half-life is true? A) It is the time it takes for half of the drug to be eliminated from the body. B) It is the time it takes for the full effect of the drug to be felt. C) It is irrelevant when considering dosing intervals. D) It varies based on the patient’s weight only. Answer: A Rationale: Drug half-life is defined as the time required for the drug concentration to reduce by half. NCLEX Preference: Understanding pharmacokinetics. 8. A patient is prescribed a drug with a narrow therapeutic index. The nurse understands that this means: A) The drug is highly effective. B) There is a small margin between therapeutic and toxic doses. C) The drug can be taken safely without monitoring. D) The drug is ineffective for most patients. Answer: B Rationale: A narrow therapeutic index indicates a small difference between effective and toxic doses. NCLEX Preference: Monitoring high-risk medications. 9. A nurse teaches a patient that taking a medication with food can sometimes enhance its absorption. Which type of medication is most likely affected by food? A) Antibiotics B) Anticoagulants C) Lipophilic drugs D) Hydrophilic drugs Answer: C Rationale: Lipophilic drugs often require dietary fats for better absorption. NCLEX Preference: Understanding factors affecting absorption. 10. A nurse is assessing a patient who has been prescribed an opioid. What is the most critical assessment parameter for this patient? A) Respiratory rate B) Blood pressure C) Heart rate D) Temperature Answer: A Rationale: Opioids can depress respiratory function, so monitoring the respiratory rate is essential. NCLEX Preference: Safety assessments in opioid administration

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Test Bank For Mosby's Pharmacology in
Nursing - Elsevier eBook on VitalSource,
22nd Edition
Author :
By Leda M. McKenry

,Chapter 1 Orientation to Pharmacology


1. The nurse is explaining pharmacology to a group of students. What does
pharmacology primarily study?
A) How drugs are administered
B) The therapeutic uses of drugs
C) The effects of drugs on the body
D) The cost-effectiveness of medications
Answer: C
Rationale: Pharmacology is the study of how drugs affect the body,
including mechanisms of action, therapeutic effects, and side effects.
NCLEX Focus: Basics of pharmacology
2. A patient asks the nurse how medications are classified. Which of the
following is the best description of drug classification?
A) Drugs are classified based on their chemical properties
B) Drugs are classified based on their therapeutic uses
C) Drugs are classified based on the pharmacy where they are made
D) Drugs are classified based on patient age
Answer: B
Rationale: Drugs are typically classified by their therapeutic use or their
effects on particular body systems.
NCLEX Focus: Drug classification
3. The nurse is preparing to administer a drug to a patient. What is the
first step in ensuring medication safety?
A) Checking the patient's ID band
B) Reviewing the patient's allergy history
C) Confirming the drug dosage
D) Reading the medication label
Answer: B
Rationale: Reviewing a patient’s allergy history is critical to prevent
allergic reactions.
NCLEX Focus: Safety - medication administration
4. Which of the following is an important nursing responsibility when
administering medications?
A) Determining the drug's cost
B) Documenting the administration of the medication
C) Calculating the pharmacy's profit
D) Choosing the manufacturer

, Answer: B
Rationale: Proper documentation of medication administration is a crucial
nursing responsibility to ensure patient safety and legal accuracy.
NCLEX Focus: Medication administration
5. A nurse is explaining the difference between generic and brand-name
drugs. What is the key difference?
A) Generic drugs have different active ingredients
B) Brand-name drugs are less effective
C) Generic drugs are usually less expensive
D) Brand-name drugs are safer
Answer: C
Rationale: Generic drugs typically cost less but have the same active
ingredients as brand-name drugs.
NCLEX Focus: Drug classification
6. The nurse is assessing a patient who is taking multiple medications.
What term is used to describe the use of multiple medications by a
patient?
A) Monotherapy
B) Polypharmacy
C) Drug synergy
D) Tolerance
Answer: B
Rationale: Polypharmacy refers to the use of multiple medications, often
seen in older adults or patients with chronic conditions.
NCLEX Focus: Safety - polypharmacy
7. Which of the following factors is most likely to affect a drug's
absorption?
A) The patient's gender
B) The route of administration
C) The patient's eye color
D) The patient's job
Answer: B
Rationale: The route of administration (oral, IV, etc.) has a significant
impact on the absorption rate of a drug.
NCLEX Focus: Pharmacokinetics - absorption
8. A nurse is reviewing the concept of bioavailability with a patient. What
does bioavailability refer to?
A) The time it takes for a drug to work
B) The percentage of the drug that reaches the bloodstream
C) The amount of the drug metabolized by the liver

, D) The effect of the drug on target cells
Answer: B
Rationale: Bioavailability refers to the proportion of a drug that enters the
bloodstream and is available for action.
NCLEX Focus: Pharmacokinetics - bioavailability
9. The nurse is caring for a patient who has taken an overdose of a
medication. What term describes the harmful effects of a drug when
taken in excessive amounts?
A) Tolerance
B) Toxicity
C) Dependence
D) Resistance
Answer: B
Rationale: Toxicity occurs when a drug is taken in excessive amounts,
leading to harmful effects.
NCLEX Focus: Safety - overdose and toxicity
10.The nurse is explaining drug distribution to a patient. Which of the
following is most important for drug distribution in the body?
A) The drug’s half-life
B) Blood flow to tissues
C) The color of the drug
D) The route of administration
Answer: B
Rationale: Blood flow to tissues is essential for proper distribution of the
drug throughout the body.
NCLEX Focus: Pharmacokinetics - distribution
11.A nurse is caring for a patient with liver disease. How might liver
disease affect drug metabolism?
A) The drug will be excreted faster
B) The drug will be metabolized slower
C) The drug will have no effect on the body
D) The drug will work faster
Answer: B
Rationale: Liver disease can impair drug metabolism, leading to a slower
breakdown of drugs and potential drug accumulation.
NCLEX Focus: Pharmacokinetics - metabolism
12.Which of the following describes the process of a drug being broken
down and converted to an inactive form in the body?
A) Absorption
B) Distribution

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