Blood Banking Chapter 11 Review Questions with complete Solutions 100%+

Blood Banking Chapter 11 Review Questions with complete Solutions 100%+ A newborn phenotypes as group O, D-positive with a 1+ direct antiglobulin test. The mother's antibody screening test is negative. Assuming the antibody screen is valid, one should consider the reason for the positive DAT is due to an antibody against __________ antigen - Answers D antigen (Rh)?? ABO ?? Select the situation where the administration of Rh immune globulin would be contraindicated. MOTHER NEWBORN A. r"r; no antibody detected Ror; DAT negative B. rr; no antibody detected R1r; DAT negative C. Rr; anti-E detected R2r; DAT positive D. r"r; 4+ anti-D detected R2r: DAT positive - Answers Rr; anti-E detected R2r; DAT positive and r"r; 4+ anti-D detected DAT positive Select the true statement regarding ABO hemolytic disease of the fetus and newborn - Answers The frequency of ABO hemolytic disease of the fetus and newborn is greater than Rh hemolytic disease of the fetus and newborn. In testing amniotic fluid, the Liley method of predicting the severity of hemolytic disease of the fetus and newborn is based on - Answers change in optical densiy measured at 450 nm What is the most common antibody specificity associated with hemolytic disease of the fetus and newborn - Answers Anti A, B Amniotic fluid analysis showed a marked increase into zone III of the Liley graph. Lecithin-sphingomyelin ratios indicated that the fetal lungs were not mature. Select the most appropriate decision regarding medical intervention. - Answers An intrauterine transfusion To prevent graft-versus-host disease, red blood cells prepared for intrauterine transfusions should be - Answers Irradiated The Kleihauer Betke test was performed using a 1-hour postdelivery maternal blood sample. Results: 10 fetal cells/1000 cells counted It is the policy to add 1 vial of Rh immune globulin to the calculated dose when the estimated volume of the hemorrhage exceeds 30 mL of whole blood. Calculate the number of vials of Rh immune globulin that would be indicated under these circumstances - Answers 3 Which elution method is ideal in the investigation of ABO hemolytic disease of the fetus and newborn - Answers Freeze-thaw Which of the following best describes the principle of the Kleihauer-Betke test - Answers Fetal hemoglobin is resistant to acid elution and remains in the cell to stain pink, whereas adult cells appear as ghost cells. All of the following are goals of an exchange transfusion except to - Answers restore the platelet count Why is reverse grouping omitted in the neonatal period for ABO testing - Answers the antibody titer levels are generally too low for detection To identify the cause of suspected hemolytic disease of the fetus and newborn, which tests are performed - Answers ABO, D, DAT All of the following are common characteristics of ABO hemolytic disease of the fetus and newborn except: - Answers Mother is group A Which of the following antibodies have not been known to cause hemolytic disease of the fetus and newborn - Answers Anti-Lea A group O, D-positive mother gave birth to an A-negative infant. After 24 hours, the newborn's bilirubin level rose to 19 mg/dL. A direct antiglobulin test performed on the cord blood specimen was positive with anti-IgG. What is the most probable antibody causing this - Answers ABO anti A, B Anti-D in the serum of a third-trimester pregnant woman with a titer of 16 is indicative of - Answers presence of Rh Immune globulin administered at 28 weeks Rh immune globulin should be given within how many hours following delivery - Answers 72 A 300-µg dose of Rh immune globulin contains sufficient anti-D to protect against how much whole blood - Answers 30 ml Which of the following is true regarding the rosette test - Answers The test is valid only if the mother is D-negative and the infant is D-positive To be considered a candidate for Rh immune globulin, the mother is __________ and the infant is __________. - Answers D negative, D positive During a first-trimester prenatal examination, it was determined that a pregnant woman was group A, D-negative with an anti-D titer of 8. What is the most likely course of action - Answers baseline is determined to be repeated in 4 to 6 week intervals. Rh immune globulin contains - Answers IgG anti D In which type of hemolytic disease of the fetus and newborn is the first-born affected - Answers ABO