NEONATAL HEMATOLOGY EXAM QUESTIONS WITH COMPLETE ANSWERS { GRADED A+}

NEONATAL HEMATOLOGY EXAM

QUESTIONS WITH COMPLETE

ANSWERS { GRADED A+}




Delivers O2 from lungs to tissues - ✔✔hemoglobin


fetal Hgb is a major component by _____ wks gestation - ✔✔10


transition begins at end of fetal life; RBCs contain ______% of HgbF at

birth - ✔✔70-90%


fetal Hgb has increased affinity for oxygen which results in increase or

decreased O2 release to tissues? - ✔✔decreased - blue baby at birth!!


T/F? Hct values increase immediately after birth - ✔✔TRUE

,formation, production, and maintenance of blood cells -

✔✔hematopoiesis


Where does hematopoiesis occur in the fetus? - ✔✔yolk sac (3-6 wks)


liver (6-16 wks)

bone marrow (predominates after 22-24 wks)


production of erythrocytes (RBCs) - ✔✔erythropoiesis


erythropoiesis is increased in response to? - ✔✔anemia and low oxygen


Erythropoiesis and synthesis of hemoglobin are regulated by the

hormone? - ✔✔erythropoietin


erythropoietin production is increase in response to ______ and

______ and decreased in response to ______ - ✔✔anemia and low

oxygen availability




hypertransfusion

, low oxygen pressure causes the kidneys and liver to release

erythropoietin which stimulates the production of RBC that carry

oxygen to the tissues increasing the oxygen carrying capacity; once the

oxygen carrying capacity is increased, the production of erythropoietin

is inhibited- this is called? - ✔✔negative feedback loop


_______ cause hematopoietic stem cell to become any formed cell

needed - ✔✔colony stimulating factors


Sites of extramedullary hematopoiesis which are _______ aid

production of cells during fetal life when long bones are small -

✔✔liver, spleen, thymus, kidneys


What are RBC function? - ✔✔tissue oxygenation by Hgb transport


CO2 removal through reaction with carbonic anhydrase

Hgb can serve as a buffer to maintain acid-base balance


life span of RBC in adult, term infant, preterm infant? - ✔✔adult: 100-

120 days