QUESTIONS AND ANSWERS 100%
CORRECT!
Doxorubicin - ANSWER Cardiotoxic
TISSUE VESICANT
Baseline MUGA and total dose (CONCERN at 550 mg/m2)
URINE=RED
IF EXTRAVASATION OCCURS= cool/ice + Totect
Idamycin - ANSWER Cardiotoxic (cardiomyopathy)
Bleomycin - ANSWER AVOID oxygen supplementation
Methotrexate - ANSWER *Leukovorin decreases cytotoxicity*
Pemetrexed - ANSWER Vitamin B12 & folic acid supplements to decrease toxicity
Fludarabine - ANSWER Immunosuppression
Thioguanine - ANSWER Bone Marrow Suppression
Stomatitis/Mucositis
5-FU - ANSWER *Stomatitis
Bone marrow depression
*Diarrhea
Mucositis
Capeticibine - ANSWER ***Pro-drug that converts 5FU in liver
Stomatitis & mucositis
Palmar-plantar erythrodysthesias (hand foot syndrome)
Cytarabine or Cytosine Arabinoside - ANSWER Cerebellar neurotoxicity
Gemcitabine - ANSWER Radiosensitizer DO NOT GIVE W/ RADIATION, except at very
low doses