what is pharmacodynamics? Correct Answer-the study of drug
mechanisms that produce biochemical/physiological changes in body
(how drug effects body)
what is drug action? Correct Answer-how a drug exerts its desired
effects (classified by their actions) -> Ex; vasodilators act by dilating
vessels
what is the drug effect Correct Answer-the response that happens from
the drug action
what is a drug receptor? Correct Answer-an part of tissue or cell that a
drug can bind to and initiate its effects
what is the difference between selective, non-selective, and specific
effects that drugs have when finding receptors? Correct Answer--
selective effects (drugs only like B1 receptors)
- non-selective (drugs will go for any B receptor -B1 in cardiac, B2 in
lungs)
- specificity ( drug will only like 1 specific B1 receptor)
what is something we can keep in mind for non-selective drugs? Correct
Answer-they can cause side effects because they go for any B receptor
, what triggers a biological response with receptors? Correct Answer-the
drug being recognized by receptor (agonist tips the equilibrium so more
of receptors are activated)
what is the role of a drug receptor ? Correct Answer-- set qualitative
relationship between drug dose and pharmacological response (more
drugs filling receptor, more response)
- mediate between blocking drug effect and stimulating it
what 4 factors determine the way a receptor will response to drug?
Correct Answer-1. Affinity (strength of binding - high or low)
2. Efficacy (drugs ability to stimulate receptor to cause response after it
binds)
3. Potency (ability of set dose to elicit maximum effect)
4. Quantity (amount of drug that reaches receptor)
what is an agonist? Correct Answer-drug that binds with receptor to
stimulate/produce effect (has high affinity)
what Is an agonist's intrinsic activity? Correct Answer-drugs ability to
initiate response after binding
why do agonists have high affinity for activating cell receptors? Correct
Answer-they resemble naturally occurring
hormones/transmitters/enzymes (but they act longer than the natural
substances they mimic)