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Research Animal Management Exam 1 part 1 Questions with Verified Answers

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What are the various levels of technician certification offered by the American Association of Laboratory Animal Science (AALAS)? - Answer-ALAT, LAT, LATG Which organization recognizes a Veterinary Technician Specialty (VTS) in Laboratory Animal Medicine? - Answer-Academy of Laboratory Animal Veterinary technicians and nurses List reasons why we use laboratory animals - Answer--The rapid rise of medical knowledge after 1800 can be attributed in large part to the increased use of lab animals - it is not always possible to find substitutes for laboratory animals -the study of bacteria, tissue culture, and computer simulation can give important information but lack the complexity of an entire organism how have animals used in biomedical research facilitated advances in medicine and science? - Answer--Provided advances in medicine and science -Higher-order animals are best predictors of complex biomedical responses of humans What is the Food, Drug and Cosmetic Act of 1938 and why was it passed? - Answer-untested products led to the human deaths -improperly prepared sulfonamide antibiotic led to mass poisoning and death of more than 100 people what can the term "cruelty-free" imply? - Answer-unregulated and not clearly defined by law. therefore, can imply many things: -neither product no ingredients have ever been tested on animals (highly unlikely) -ingredients tests on animals, but not the final product -testing done in foreign country what percentage of animals used in research are made up of mice and rats? - Answer-85-95% what are the two primary public granting agencies discussed in class? - Answer-National Institutes of Health (NIH) National Science Foundations (NSF) what does AAALAC stand for and what do they do? - Answer-Association of Assessment of Laboratory Animal Care -they voluntary put standards in place to apply federal and state and local levels to obey the laws

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Research Animal Management Exam 1
part 1 Questions with Verified Answers
What are the various levels of technician certification offered by the American
Association of Laboratory Animal Science (AALAS)? - Answer-ALAT, LAT, LATG

Which organization recognizes a Veterinary Technician Specialty (VTS) in Laboratory
Animal Medicine? - Answer-Academy of Laboratory Animal Veterinary technicians and
nurses

List reasons why we use laboratory animals - Answer--The rapid rise of medical
knowledge after 1800 can be attributed in large part to the increased use of lab animals
- it is not always possible to find substitutes for laboratory animals
-the study of bacteria, tissue culture, and computer simulation can give important
information but lack the complexity of an entire organism

how have animals used in biomedical research facilitated advances in medicine and
science? - Answer--Provided advances in medicine and science
-Higher-order animals are best predictors of complex biomedical responses of humans

What is the Food, Drug and Cosmetic Act of 1938 and why was it passed? - Answer-
untested products led to the human deaths
-improperly prepared sulfonamide antibiotic led to mass poisoning and death of more
than 100 people

what can the term "cruelty-free" imply? - Answer-unregulated and not clearly defined by
law. therefore, can imply many things:
-neither product no ingredients have ever been tested on animals (highly unlikely)
-ingredients tests on animals, but not the final product
-testing done in foreign country

what percentage of animals used in research are made up of mice and rats? - Answer-
85-95%

what are the two primary public granting agencies discussed in class? - Answer-
National Institutes of Health (NIH)
National Science Foundations (NSF)

what does AAALAC stand for and what do they do? - Answer-Association of
Assessment of Laboratory Animal Care
-they voluntary put standards in place to apply federal and state and local levels to obey
the laws

, what does IACUC stand for and what are the roles of this committee? - Answer-
Institutional Animal Care and Use Committee
-meetings once a monthly
-review and approve animal protocols
-authorize extension of protocols
-authorize extension of protocols
-attend researcher's concerns
-suspect protocols not in compliance
-communicate with PI
-inspect animal housing facilities
-keep records

what information should an IACUC protocol include? - Answer--proposed animal care
and use
-justify use of animals
-assurance that study is not unnecessary duplication
-staff have adequate training
-alternative have been considered
-activities that may include animal pain or distress are scientifically necessary

what are the 3Rs of animal research? - Answer-refinement, replacement, reduction

describe the difference between "animal rights" and "animal welfare" - Answer-animal
rights
-animals have the same equality and protection as humans
-animal use is viewed are exploitations and should be banned

animal welfare
-animals can be used but must be treated humanely
-animal's physical and psychological well-being is met

what is the Animal Welfare Act (AWA) and in what year was it first passed? - Answer-
passed in 1966
the first law that protected nonfarm animals in the United States

which agency enforces the regulations established under the Animal Welfare Act? -
Answer-responsibility for administration and enforcement delegated to the USDA's
animal care programs of Animal and Plant Health Inspection Service (APHIS)

the AWA establishes minimal care standards for which regulated species used in
research? - Answer-dogs, cats, primates, rabbits, hamsters and guinea pigs

Public Health Service (PHS) Policy regarding the use of animals in research applies to
which animal species? - Answer-use of all live vertebrate animals

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