Radiation Therapy Exam Questions and
Answers Latest Update
roentgen - Answer-who defined radiation oncology in 1928 - the key to modern radiation
oncology?
radiation oncology - Answer-_____ ______: The utilization of ionizing radiation in the
treatment of disease
cell mitosis, oxygenated - Answer-ionization is most effective during ___ _____ and in
well ______ conditions
DNA - Answer-Then it appears oxygen fixes the lesion and the target molecule is _____
direct - Answer-______ effect: the target molecule is ionized and it is most likely DNA
considering sensitivity during mitosis
indirect - Answer-______ effect: another molecule is ionized and the energy is
chemically transferred to the target molecule (DNA). H2O is thought to be the primary
source of unstable chemical elements which result from combination with free O2
indirect - Answer-Due to the prevalence of H2O and the importance of O2 in cell kill we
believe most damage results from _____ effect.
oxygen enhancement ratio - Answer-______ _____ _____: dose hypoxic / dose
oxygenated This ratio is 3 to 1 for the clinical range of x-radiation
reproductive death - Answer-_______ _____: the major effect of radiation on dividing
cells. Cells fail to produce viable progeny
interphase death - Answer-______ ______: seen in non-dividing cells such as mature
nervous system or muscle tissues. Cells simply lose the ability to function and
die...typically at high doses of radiation.
fractionation - Answer-______: A tumor tends to outgrow its blood supply. By dividing
the total dose into a number of relatively small daily doses (fractions) the tumor is
allowed to reoxygenate. This also allows normal cells to repair PLD (potentially lethal
damage)
therapeutic ratio - Answer-_____ _____: Typically this determines the curability of a
lesion and the decision to treat. Defined as the Normal Tissue Tolerance / Tumor
Control Dose. Practically, the tumor control dose depends on the tissue of origin and the
size of the tumor
, Seminoma
Hodgkins Disease
Neuroblastoma
Wilms Tumor
Larynx
Squamous Cell less than 4cm - Answer-what are some different types of radiocurable
tumors?
3500-6000 rads - Answer-what exposure dose is typically used for radiocurable tumors?
6000-7500 - Answer-Size typically greater than 2cm but less than 4cm with cureative
doses of ____-______rads
Oral Cavity
Pharynx
Bladder
Cervix & Uterus
Ovary
Lung - Answer-what are some of the different types of tumors that are less than 4cm but
greater than 2cm that are radiocurable?
8000 and above - Answer-what is the curative dose range for the least radiocurable
tumors?
Large to massive squamous cell and adenocarcinoma greater than 4cm in diameter -
Answer-what are some examples of the least radiocurable tumors?
definitive - Answer-______ treatment: patient treated for cure. Typically a four to six
week course of therapy
palliative - Answer-_______ treatment: treatment is to alleviate symptoms such as:
pain
bleeding
obstruction
paralysis
teletherapy - Answer-______: use of external beam treatment from high energy x-rays
or gamma rays. Used to treat a relatively large tissue volume to a low to moderate dose.
brachytherapy - Answer-_______: implant a radioactive source close to the lesion. Used
to treat a small volume to a high dose. May be
intracavitary - gyn
or
interstial - prostate, base of tongue, breast
Answers Latest Update
roentgen - Answer-who defined radiation oncology in 1928 - the key to modern radiation
oncology?
radiation oncology - Answer-_____ ______: The utilization of ionizing radiation in the
treatment of disease
cell mitosis, oxygenated - Answer-ionization is most effective during ___ _____ and in
well ______ conditions
DNA - Answer-Then it appears oxygen fixes the lesion and the target molecule is _____
direct - Answer-______ effect: the target molecule is ionized and it is most likely DNA
considering sensitivity during mitosis
indirect - Answer-______ effect: another molecule is ionized and the energy is
chemically transferred to the target molecule (DNA). H2O is thought to be the primary
source of unstable chemical elements which result from combination with free O2
indirect - Answer-Due to the prevalence of H2O and the importance of O2 in cell kill we
believe most damage results from _____ effect.
oxygen enhancement ratio - Answer-______ _____ _____: dose hypoxic / dose
oxygenated This ratio is 3 to 1 for the clinical range of x-radiation
reproductive death - Answer-_______ _____: the major effect of radiation on dividing
cells. Cells fail to produce viable progeny
interphase death - Answer-______ ______: seen in non-dividing cells such as mature
nervous system or muscle tissues. Cells simply lose the ability to function and
die...typically at high doses of radiation.
fractionation - Answer-______: A tumor tends to outgrow its blood supply. By dividing
the total dose into a number of relatively small daily doses (fractions) the tumor is
allowed to reoxygenate. This also allows normal cells to repair PLD (potentially lethal
damage)
therapeutic ratio - Answer-_____ _____: Typically this determines the curability of a
lesion and the decision to treat. Defined as the Normal Tissue Tolerance / Tumor
Control Dose. Practically, the tumor control dose depends on the tissue of origin and the
size of the tumor
, Seminoma
Hodgkins Disease
Neuroblastoma
Wilms Tumor
Larynx
Squamous Cell less than 4cm - Answer-what are some different types of radiocurable
tumors?
3500-6000 rads - Answer-what exposure dose is typically used for radiocurable tumors?
6000-7500 - Answer-Size typically greater than 2cm but less than 4cm with cureative
doses of ____-______rads
Oral Cavity
Pharynx
Bladder
Cervix & Uterus
Ovary
Lung - Answer-what are some of the different types of tumors that are less than 4cm but
greater than 2cm that are radiocurable?
8000 and above - Answer-what is the curative dose range for the least radiocurable
tumors?
Large to massive squamous cell and adenocarcinoma greater than 4cm in diameter -
Answer-what are some examples of the least radiocurable tumors?
definitive - Answer-______ treatment: patient treated for cure. Typically a four to six
week course of therapy
palliative - Answer-_______ treatment: treatment is to alleviate symptoms such as:
pain
bleeding
obstruction
paralysis
teletherapy - Answer-______: use of external beam treatment from high energy x-rays
or gamma rays. Used to treat a relatively large tissue volume to a low to moderate dose.
brachytherapy - Answer-_______: implant a radioactive source close to the lesion. Used
to treat a small volume to a high dose. May be
intracavitary - gyn
or
interstial - prostate, base of tongue, breast
