solutions 2024/2025
Antibody - ANSWER-a substance produced by the body that destroys or
inactivates an antigen that has entered the body
What are the actions of antibodies - ANSWER--Opsonization ( marks for
phagocytosis, changes charge to make visible to phagocytes and to repel other
cells)
- Agglutination
-Neutralisation
-Activation of complement (recruits MAC attach complex)
-Antibody-mediated cytotoxicity
IgA - ANSWER-LOCATION: mucusal areas (gut, respiratory tract, urogenital tract),
tears, saliva, breast milk
FUNCTION: prevents colonisation by pathogens
Dimer
IgD - ANSWER-LOCATION: On B-cells that haven't been exposed to antigens
FUNCTION: As BCR, activate basophils + mast cells, produce antimicrobial
factors
Monomer
IgE - ANSWER-FUNCTION: binds to allergens, triggers histamine release (mast
cells + basophils), involved in parasite destruction