What is acute glomerulonephritis? - Answers Inflammation of the membrane tissue in the kidneys that
serve as a filter (glomeruli)
How many glomeruli are in each kidney? - Answers About 1 million
How does filtration work? - Answers Blood gets filtered through glomerulus and takes back what it
needs and extra fluid/waste passes into tubules to become urine.
What occurs in glomerular disease? - Answers Damage to glomeruli allows protein and RBC to leak into
urine.
What are the 2 types of glomerular disease? - Answers Acute and chronic.
What are the causes of acute glomerular disease? - Answers Infections (strep throat), lupus, and
goodpasture.
What type of infection typically causes acute glomerulonephritis? - Answers Some type of strep
infection. Like strep throat or a skin infection.
Why does the strep infection cause acute issues? - Answers Certain strep antigens resemble the
basement membrane of the glomerulus resulting in causing an antigen antibody forming which gets
caught in the glomerulus causing an inflammatory response.
What does this strep related inflammation response do? - Answers Causes swelling and break downs
glomeruli capillaries.
Which form of lupus causes glomerulonephritis? - Answers Lupus SLE (systemic lupus erythematosus)
What else can lupus sle effect? - Answers Many other parts of body such as joints, skin, kidneys, heart,
and lungs.
What is goodpasture disease/syndrome? What does it do? - Answers It is an autoimmune disease. It
creates substances that attack a protein that can get into air sacks in lungs or glomeruli of kidneys.
What are the clinical manifestations of acute glomerulonephritis? - Answers Albuminuria, hematuria, ↓
GFR, hypoproteinemia, edema, ↑ BP, fatigue, and anemia.
What is albuminuria? - Answers Large amounts of protein in the urine.
What is hematuria? - Answers Blood in the urine.
What is ↓ GFR? - Answers inefficient filtering of wastes from the blood.
What is hypoproteinemia? - Answers low blood protein.
What is a s/s of albuminuria? - Answers Excessively foamy or bubbly urine.