ABSITE -- Biliary
What is Charcot's triad and Reynold's Pentad? - ANSFever*
Jaundice*
Right upper quadrant pain*
Shock
Altered intellectual fame
**charcot's triad
What is step one in control of acute cholangitis? - ANSInitiation of IVF and antibiotics
Supportive take care of septic surprise, which may additionally encompass starting
vasopressors
**in 15% of instances, pressing (within 12-24 hours) endoscopic retrograde
cholangiopancreatography (ERCP) or percutaneous transheptic cholangiography (PTC) may
additionally need to be accomplished** however the first step is resuscitation and abx
What are the three maximum commonplace reasons of cholangitis?
What is the most commonplace micro organism associated with it?
What antibiotic insurance must you include? - ANSBiliary calculi
Malignancy
Benign strictures
E coli is the most common bacterial isolate
Klebsiella
Enterobacter
Enterococcus
*Typically deal with with piperacillin-tazobactam with a purpose to have Pseudomonas
insurance
If you've got multiplied Alanine aminotransferase (ALT) what are the related ailment
pathologies? - ANSViral hepatitis (Hep C, B)
Diabetes
Congestive coronary heart failure
Liver damage
Bile duct issues
Infectious mononucleosis
Myopathy
If you have got multiplied Aspartate aminotransferase (AST) what are the associated ailment
pathologies? - ANSMyocardial infarction
Acute pancreatitis
, Acute hemolytic anemia
Severe burns
Acute renal ailment
Musculoskeletal diseases
Trauma
If you have got multiplied Alkaline phosphatase (ALP) what are the associated disease
pathologies? - ANSBiliary obstruction
Osteoblastic bone tumors
Osteomalacia
Osteoporosis
Hepatitis
Cirrhosis
Acute cholecystitis
Myelofibrosis
Leukemoid reaction
Lymphoma
Paget ailment
Sarcoidosis
Hyperthyroidism
Hyperparathyroidism
Myocardial infarction
Pregnancy
If you've got increased Total bilirubin (T bili) what are the associated disorder pathologies? -
ANSHemolysis
Gilbert syndrome (slight liver disease wherein the liver does not well technique bilirubin.
Gilbert's syndrome is because of a mutation within the UGT1A1 gene)
Rotor syndrome (Rare reason of combined direct and indirect hyperbilirubinemia, noticeably
benign, autosomal recessive bilirubin ailment characterized by way of non-hemolytic
jaundice because of the persistent elevation of predominantly conjugated bilirubin)
Hepatitis
Biliary obstruction
Crigler-Najjar syndrome (Rare inherited disease affecting the metabolism of bilirubin, a
chemical fashioned from the breakdown of the heme in red blood cells leading to
nonhemolytic jaundice, which leads to excessive levels of unconjugated bilirubin and
frequently leads to brain harm in toddlers, autosomal recessive way)
Dubin-Johnson syndrome (Rare, autosomal recessive, benign sickness that reasons an
remoted boom of conjugated bilirubin in the serum. Classically, the circumstance causes a
black liver because of the deposition of a pigment similar to melanin. This situation is related
to a defect in the ability of hepatocytes to secrete conjugated bilirubin into the bile, and is
similar to Rotor syndrome)
Cirrhosis
**ought to differentiate between direct and indirect to decide etiology of pathology
If you've got improved Lipase what are the associated ailment pathologies? - ANSPancreatic
obstruction
Pancreatic destruction
What is Charcot's triad and Reynold's Pentad? - ANSFever*
Jaundice*
Right upper quadrant pain*
Shock
Altered intellectual fame
**charcot's triad
What is step one in control of acute cholangitis? - ANSInitiation of IVF and antibiotics
Supportive take care of septic surprise, which may additionally encompass starting
vasopressors
**in 15% of instances, pressing (within 12-24 hours) endoscopic retrograde
cholangiopancreatography (ERCP) or percutaneous transheptic cholangiography (PTC) may
additionally need to be accomplished** however the first step is resuscitation and abx
What are the three maximum commonplace reasons of cholangitis?
What is the most commonplace micro organism associated with it?
What antibiotic insurance must you include? - ANSBiliary calculi
Malignancy
Benign strictures
E coli is the most common bacterial isolate
Klebsiella
Enterobacter
Enterococcus
*Typically deal with with piperacillin-tazobactam with a purpose to have Pseudomonas
insurance
If you've got multiplied Alanine aminotransferase (ALT) what are the related ailment
pathologies? - ANSViral hepatitis (Hep C, B)
Diabetes
Congestive coronary heart failure
Liver damage
Bile duct issues
Infectious mononucleosis
Myopathy
If you have got multiplied Aspartate aminotransferase (AST) what are the associated ailment
pathologies? - ANSMyocardial infarction
Acute pancreatitis
, Acute hemolytic anemia
Severe burns
Acute renal ailment
Musculoskeletal diseases
Trauma
If you have got multiplied Alkaline phosphatase (ALP) what are the associated disease
pathologies? - ANSBiliary obstruction
Osteoblastic bone tumors
Osteomalacia
Osteoporosis
Hepatitis
Cirrhosis
Acute cholecystitis
Myelofibrosis
Leukemoid reaction
Lymphoma
Paget ailment
Sarcoidosis
Hyperthyroidism
Hyperparathyroidism
Myocardial infarction
Pregnancy
If you've got increased Total bilirubin (T bili) what are the associated disorder pathologies? -
ANSHemolysis
Gilbert syndrome (slight liver disease wherein the liver does not well technique bilirubin.
Gilbert's syndrome is because of a mutation within the UGT1A1 gene)
Rotor syndrome (Rare reason of combined direct and indirect hyperbilirubinemia, noticeably
benign, autosomal recessive bilirubin ailment characterized by way of non-hemolytic
jaundice because of the persistent elevation of predominantly conjugated bilirubin)
Hepatitis
Biliary obstruction
Crigler-Najjar syndrome (Rare inherited disease affecting the metabolism of bilirubin, a
chemical fashioned from the breakdown of the heme in red blood cells leading to
nonhemolytic jaundice, which leads to excessive levels of unconjugated bilirubin and
frequently leads to brain harm in toddlers, autosomal recessive way)
Dubin-Johnson syndrome (Rare, autosomal recessive, benign sickness that reasons an
remoted boom of conjugated bilirubin in the serum. Classically, the circumstance causes a
black liver because of the deposition of a pigment similar to melanin. This situation is related
to a defect in the ability of hepatocytes to secrete conjugated bilirubin into the bile, and is
similar to Rotor syndrome)
Cirrhosis
**ought to differentiate between direct and indirect to decide etiology of pathology
If you've got improved Lipase what are the associated ailment pathologies? - ANSPancreatic
obstruction
Pancreatic destruction
