pancreas is connected to?✔️✔️the small intestine
Endocrine islet of langerghans are made up of three cell types✔️✔️Alpha cells, beta cells,
and delta cells
Alpha cells make?✔️✔️Glucagon which stimulates glycogen into glucose glycogenolysis.
Beta cells make✔️✔️Insulin which promotes glycogenesis and lowers glucose levels
Delta cells make✔️✔️Gastrin and somatostatin
Amylase✔️✔️Break down startch and glycogen. Increased in acute panncreatitis
Lipase✔️✔️Hydrolyzes fats to make alcohols and fatty acids. Increased in acute pancreatis.
Cystic Fibrosis✔️✔️genetic dysfunction of exocrine glands like liver lungs saliva glands
pulmonary disease intestinal malabsorption caused by lack of pancreatic enzymes excretion
pancreatitis✔️✔️pancreas inflammation seenwith alcohol abuse gallbladder disorder can be
acute or chroniccaused by release of pancreatic enzymes from cells into surrounding
pancreatic tissue
Diabetis mellitus✔️✔️Type I and II and GD notenough insulin that leads to hyperglycemia
and the destruction of beta cells
, pancreatic cancer✔️✔️5% survival rate seen in pancreatic dust insulinoma at the beta cells
in islets increased insulin and hypoglycemia
Pancreatic exocrine Function test✔️✔️Secretin. Quantitative fecal fat. Sweat cl
test(pilocarpine nitrate stimulated sweating). Enzyme testing(amaylase lipase)
Glycogenesis✔️✔️Glycogen formation from glucose
Glycogenolysis✔️✔️Glycogen breakdown to glucose
Glycolysis✔️✔️Catabolism of glucose to pyruvate for ATP
Gluconeogenesis✔️✔️Formation of glucose from aa and lipids
Fasting plasma glucose for diabetes✔️✔️> or = 126 mg/dL
2 hr post prandial plasma glucose for diabetes✔️✔️> or = 200 mg/dL
OGTT oralglucose tolerance test for diabetes✔️✔️> or = 200
Nonlactose fermenting, hydrogen sulfide producing, indole and VP negative but utilises
citrate as a source of carbon✔️✔️Salmonella
Rh haplotype among whites✔️✔️DCe
antinuclear antibody (ANA) testing pattern for homogeneous✔️✔️nucleus (nuclei) of the
interphase cell smooth staining in the nucleus of the interphase cells