Questions with Correct Answers
what should you test when you want to see extrinsic problems? Correct
Answer-PT
what should you test when you want to see intrinsic problems? Correct
Answer-ptt
this hematologic disorder happens when the platelet count is <150,000;
can be inherited or acquired thru high doses of ASA/chemo meds that ->
accelerated platelet destruction Correct Answer-thrombocytopenia
thrombocytopenia, due to drugs, is caused by accelerated platelet
destruction because antibodies attack the platelets. what will this cause?
Correct Answer-bleeding
what are SSx of bleeding? Correct Answer-bleeding gums/poop,
petechiae, purpura, ecchymosis
this type of thrombocytopenia is idiopathic; can be autoimmune; is the
most common acquired thrombocytopenia; happens when the
destruction of platelets is abnormal Correct Answer-ITP (immune
thrombocytopenic purpura)
is the normal platelet survival time? Correct Answer-8-10 days
(shortened w/ ITP)
, what is the patho behind ITP? Correct Answer-immune system creates
antibodies that attach to platelets-> spleen sees something foreign->
platelets destroyed
what labs would we see w/ ITP? Correct Answer-decreased platelets
what are SSx of ITP? Correct Answer-bleeding (especially in
gums/stool); pt easily bruised
what infections might contribute to ITP? Correct Answer-H. pylori &
viral infections
what is included in the Tx of ITP? Correct Answer-NO
ASA/PLATELET IMPAIRING MEDS; corticosteroids
(prednisone/methylprednisone); IVIG if unresponsive to steroids;
rituximab; splenectomy if unresponsive to steroids or IVIG;
immunosuppressive (azathioprine (Imuran)); platelet transfusion if count
>10,000
why would we give corticosteroids to a pt w/ ITP? Correct Answer-
suppresses macrophages that destroy the platelets and thereby increasing
the platelet life span
why would we want to avoid ASA/platelet impairing meds w/ ITP?
Correct Answer-they need to bleed LESS (not more)