1
TEST BANK FOR FUNDAMENTALS OF MOLECULAR
VIROLOGY 2ND EDITION BY ACHESON.
Page 1 of 255
,Package Title: Testbank
Course Title: Acheson 2nd edition
Chapter Number: 01
Question type: Multiple Choice
1) Which of the following terms describes the protein shell that surrounds the viral genome?
a) capsid
b) envelope
c) matrix
d) virion
e) capsomere
ANS:->>: a
2) Which of the following would not be a nucleic acid form found in a viral genome?
a) dsDNA
b) ssDNA
c) dsRNA
d) ssRNA
e) an RNA:DNA hybrid
ANS:->>: e
3) Which of the following is an enzyme that most RNA pathogen encode in their genome?
a) DNA-dependent-RNA-polymerase
b) RNA-dependent-RNA-polymerase
c) DNA-dependent-DNA-polymerase
d) DNA-dependent-RNA-polymerase
e) RNA-dependent-protein-synthetase
ANS:->>: b
Page 2 of 255
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4) Pathogen play a major role in the ecology of the ocean by doing which of the following?
a) By infecting photosynthetic bacteria and increasing their growth.
b) By infecting harmful bacteria found in the ocean and limiting their growth.
c) By killing off fish and preventing them from becoming too plentiful.
d) By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.
e) All of the above statements are correct.
ANS:->>: d
5) If you wanted to show that an infectious agent is a pathogen/virus, what experiment could you do?
a) Show that the agent can be seen under a light microscope.
b) Show that agent contains a lipid membrane.
c) Show that the agent can form single colonies on an agar plate.
d) Show that the agent can be diluted and can still cause disease in an animal.
e) Show that the agent can pass through a porcelain filter and is still infectious.
ANS:->>: e
6) What does the word “pathogen/virus” mean in Latin?
a) infectious agent
b) liquid
c) poison
d) death
e) disease
ANS:->>: c
7) The word “phage” is a shortened version of the name of a pathogen/virus that can infect which type of
organism?
a) bacterial cell
b) human cell
c) eukaryotic cell
d) plant cell
e) inset cell
ANS:->>: a
Page 3 of 255
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8) The study of which group of pathogen led to the discovery of cellular genes that can promoter
cancer inanimal cells?
a) papillomapathogen
b) retropathogen
c) adneopathogen
d) polyomapathogen
e) picornapathog
enANS:->>: b
9) When doing a plaque assay with human or animal cells, a layer of nutrient media mixed with agar is
put on top of the cells after they have been infected with the diluted pathogen/virus. What is the major
purpose ofthis agar layer?
a) It helps to feed the cells as they grow.
b) It promotes the replication of the pathogen/virus.
c) It makes the infected cells easier to visualize.
d) It limits the movement of pathogen/virus particles.
e) All of the above are correct.
ANS:->>: d
10) To start an experiment, you do an infection by putting 0.5 ml of a pathogen/virus stock that has a
titer of 6 x 107 pfu/ml onto a plate of animal cells that contains 5 x 10 6 cells. What is the multiplicity of
infection for this experiment?
a) 12
b) 6
c) 5
d) 3
e) 1
ANS:->>:
b
11) During a single growth cycle experiment, the titer of extracellular and intracellular pathogen/virus
drops in thefirst hour. What explains this observation?
Page 4 of 255
TEST BANK FOR FUNDAMENTALS OF MOLECULAR
VIROLOGY 2ND EDITION BY ACHESON.
Page 1 of 255
,Package Title: Testbank
Course Title: Acheson 2nd edition
Chapter Number: 01
Question type: Multiple Choice
1) Which of the following terms describes the protein shell that surrounds the viral genome?
a) capsid
b) envelope
c) matrix
d) virion
e) capsomere
ANS:->>: a
2) Which of the following would not be a nucleic acid form found in a viral genome?
a) dsDNA
b) ssDNA
c) dsRNA
d) ssRNA
e) an RNA:DNA hybrid
ANS:->>: e
3) Which of the following is an enzyme that most RNA pathogen encode in their genome?
a) DNA-dependent-RNA-polymerase
b) RNA-dependent-RNA-polymerase
c) DNA-dependent-DNA-polymerase
d) DNA-dependent-RNA-polymerase
e) RNA-dependent-protein-synthetase
ANS:->>: b
Page 2 of 255
,2
4) Pathogen play a major role in the ecology of the ocean by doing which of the following?
a) By infecting photosynthetic bacteria and increasing their growth.
b) By infecting harmful bacteria found in the ocean and limiting their growth.
c) By killing off fish and preventing them from becoming too plentiful.
d) By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.
e) All of the above statements are correct.
ANS:->>: d
5) If you wanted to show that an infectious agent is a pathogen/virus, what experiment could you do?
a) Show that the agent can be seen under a light microscope.
b) Show that agent contains a lipid membrane.
c) Show that the agent can form single colonies on an agar plate.
d) Show that the agent can be diluted and can still cause disease in an animal.
e) Show that the agent can pass through a porcelain filter and is still infectious.
ANS:->>: e
6) What does the word “pathogen/virus” mean in Latin?
a) infectious agent
b) liquid
c) poison
d) death
e) disease
ANS:->>: c
7) The word “phage” is a shortened version of the name of a pathogen/virus that can infect which type of
organism?
a) bacterial cell
b) human cell
c) eukaryotic cell
d) plant cell
e) inset cell
ANS:->>: a
Page 3 of 255
, 3
8) The study of which group of pathogen led to the discovery of cellular genes that can promoter
cancer inanimal cells?
a) papillomapathogen
b) retropathogen
c) adneopathogen
d) polyomapathogen
e) picornapathog
enANS:->>: b
9) When doing a plaque assay with human or animal cells, a layer of nutrient media mixed with agar is
put on top of the cells after they have been infected with the diluted pathogen/virus. What is the major
purpose ofthis agar layer?
a) It helps to feed the cells as they grow.
b) It promotes the replication of the pathogen/virus.
c) It makes the infected cells easier to visualize.
d) It limits the movement of pathogen/virus particles.
e) All of the above are correct.
ANS:->>: d
10) To start an experiment, you do an infection by putting 0.5 ml of a pathogen/virus stock that has a
titer of 6 x 107 pfu/ml onto a plate of animal cells that contains 5 x 10 6 cells. What is the multiplicity of
infection for this experiment?
a) 12
b) 6
c) 5
d) 3
e) 1
ANS:->>:
b
11) During a single growth cycle experiment, the titer of extracellular and intracellular pathogen/virus
drops in thefirst hour. What explains this observation?
Page 4 of 255
