Answers All Correct
Principle adverse effect is hypokalemia - Answer- Thiazides
Produce much greater diuresis than thiazides - Answer- Loop diuretics
Diuretics not used routinely for HTN - Answer- Loop diuretics
Diuretics used for low GFR and patients needing ⬆️ diuresis - Answer- Loop diuretics
Their most significant adverse effect is hyperkalemia - Answer- Potassium sparing
diuretics
Cannot be used with ACEIs, ARBs, or aldosterone agonists because these agents
promote hyperkalemia - Answer- Potassium sparing diuretics
Used to treat HTn and edema associated with 💗 failure - Answer- Loop diuretics and
thiazides
p.456
These hypertensive meds can cause REFLEX TACHYCARDIA, dizziness, gingival
hyperplasia, peripheral edema - Answer- CCBs
Dihydropyridines
p. 508
These hypertensive meds block glocogenolysis and mask early signs of hypoglycemia. -
Answer- Beta blockers
p. 511
Hypentensive drug treatment for diabetic - Answer- ACEIs, ARBs, CCBs, and diuretics
in low doses
p.511
These 2 classes of antihypertensives ⬇️ mortality and morbidity - Answer- Beta
blockers and diuretics
p.511
These drugs slow progression of renal damage and ⬇️ albuminuria - Answer- ACEIs
and ARBs
p. 511
, Drug of choice for hypertensive emergencies - Answer- Nitroprusside (IV)
Nipride
p.515
______ ⬆️ Renal excretion of potassium and - Answer- Aldosterone
_______ is the most abundant intracellular cation - Answer- Potassium
Two categories dihydropyridines (smooth muscles affected)
Nondihydropyridines (affect calcium channels) - Answer- CCB
In high doses _______ stimulates K+ uptake by cells - Answer- Insulin
What is the most modifiable risk factor for coronary heart disease, stroke, heart failure,
ESRD, pvd - Answer- Blood pressure
Do not abruptly d/c these drugs - Answer- CCB
Normal BP - Answer- <120/<80
PreHTN - Answer- 120-139/80-89
Stage I HTN - Answer- 140-159/90-99
Initial treatment of HTN in blacks including those with diabetes - Answer- Thiazides
CCBs
What is the moa for diuretics? - Answer- Affects Maintenance of ecf volume and
composition
What is the Path that urine takes through the nephron - Answer- Glomerulus▶️Prox
convol tube▶️Loop of Henle: Descrnding limb▶️Ascending limb▶️DCT▶️Collecting
duct
What is the site of action for osmotic diuretics like
Mannitol? - Answer- Proximal convoluted tubule
What is the Site of action for Thiazide diuretics like
HCTZ? - Answer- Early distal convoluted tubule
What is the (site of action for Potassium sparing diuretics like
Spironolactone? - Answer- Late distal convoluted tubule and collecting duct (distal
nephron)
What is the sote of action for Loop diuretics like