Anatomy and Physiology 1
Lecture Outline
Chapter 6
The Skeletal System: Bone Tissue
I. Functions of Bones and the Skeletal System
a. Support
b. Protection
c. Aid in movement
d. Mineral homeostasis
i. Calcium
ii. Phosphorus
e. Hemopoiesis in red bone marrow
f. Triglyceride storage in yellow marrow
II. Gross Structure of Long Bone
a. Diaphysis
b. Epiphyses
c. Metaphyses
i. Epiphyseal plate – hyaline cartilage
ii. Epiphyseal line – bone
d. articular cartilage – hyaline cartilage
e. periosteum – dense irregular CT
i. contains osteoblasts
ii. aids in fracture repair
iii. attachment point for tendons and ligaments
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, f. medullary cavity
i. contains red marrow in children
ii. contains yellow marrow in adults
g. endosteum
i. osteoblasts and connective tissue
III. Histology of Bone Tissue (Osseous tissue)
a. Introduction
i. Matrix
1. water (25%)
2. collagen fibers (25%) – flexibility
3. crystallized mineral salts (50%) – hardness
a. calcium phosphate
b. calcium carbonate
c. magnesium hydroxide
d. fluoride
e. sulfate
4. calcification
a. depositing minerals in spaces between collagen fibers
b. osteoblasts initiate calcification
b. Cells
i. Osteogenic cells
1. stem cells
2. undergo mitosis
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