PHARMACOLOGY MSN 571 NEWEST ACTUAL EXAM
COMPLETE 140 QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED A+
Prescriptive authority - ANSWER: legal authority granted to advanced practice nurses
to prescribe medication; DETERMINED BY STATE LAW
Rational Drug Selection - ANSWER: based on individual patient and addresses
disease specific information: ONLY A GUIDELINE
Drug Selection - ANSWER: includes analysis of cost, guidelines, avaibalbility,
interactions, side effects, allergies, hepatic and renal function, need for monitoring,
special precautions i.e elderly
medication education basic components - ANSWER: medication name
purpose
dosing regimen
administration
adverse effects
any storage needs
associated labs testing
food & drug interactions
duration of therapy
medication adherence - ANSWER: barriers to adherence=
forgetfulness
lack of planning
cost
dissatisfaction
altered dosing
Phamacokinetics - ANSWER: study of drug movement throughout body
principles of pharmacokinetics - ANSWER: absorption
distribution
metabolism
excretion
Passage of drugs across membranes - ANSWER: - channels and pores
- transport systems (P-glycoprotein)
- direct penetration of the membrane
Absorption of drugs - ANSWER: Transfer of drugs from site of administration across
cell membrane into the blood stream
, factors that affect absorption of drugs - ANSWER: rate of dissolution- how easy
dissolves
surface area- >surface area moves faster
blood flow- >blood flow moves faster
lipid solubility - lipid easily cross membrane
ph partitioning -
Distribution of drugs - ANSWER: movement of drugs from systemic circulation to site
of drug action
factors that determine drug flow - ANSWER: blood flow to tissues
ability to exit vascular system
ability to enter cell
Drug ability to exit vascular system - ANSWER: capillary bed- typical
blood brain barreier
placenta drug transfer
protein binding - albumin
drug ability to enter cell - ANSWER: binds with receptors on external surface of cell
membrane
drug metabolism - ANSWER: the enzymatic biotransformation of a drug structure
most occur in liver by P450 system
first pass effect - ANSWER: rapid hepatic inactivation of drug on its first pass through
liver
drug excretion - ANSWER: elimination of a drug from the body
Drug Excretion Routes - ANSWER: renal
breast milk
bile
lungs
sweat
saliva
therapeutic drug range - ANSWER: range of drug between minimum effective dose
and toxic dose. larger index - safer dose smaller index- harmful dose
drug half life - ANSWER: the time required for the amount of drug in the body to
decrease by 50%
Phamacodynamics - ANSWER: biochemical and physiological effects of drugs on body
dose-response relationship - ANSWER: the relationship between the size of an
administered dose and the intensity it produces
COMPLETE 140 QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED A+
Prescriptive authority - ANSWER: legal authority granted to advanced practice nurses
to prescribe medication; DETERMINED BY STATE LAW
Rational Drug Selection - ANSWER: based on individual patient and addresses
disease specific information: ONLY A GUIDELINE
Drug Selection - ANSWER: includes analysis of cost, guidelines, avaibalbility,
interactions, side effects, allergies, hepatic and renal function, need for monitoring,
special precautions i.e elderly
medication education basic components - ANSWER: medication name
purpose
dosing regimen
administration
adverse effects
any storage needs
associated labs testing
food & drug interactions
duration of therapy
medication adherence - ANSWER: barriers to adherence=
forgetfulness
lack of planning
cost
dissatisfaction
altered dosing
Phamacokinetics - ANSWER: study of drug movement throughout body
principles of pharmacokinetics - ANSWER: absorption
distribution
metabolism
excretion
Passage of drugs across membranes - ANSWER: - channels and pores
- transport systems (P-glycoprotein)
- direct penetration of the membrane
Absorption of drugs - ANSWER: Transfer of drugs from site of administration across
cell membrane into the blood stream
, factors that affect absorption of drugs - ANSWER: rate of dissolution- how easy
dissolves
surface area- >surface area moves faster
blood flow- >blood flow moves faster
lipid solubility - lipid easily cross membrane
ph partitioning -
Distribution of drugs - ANSWER: movement of drugs from systemic circulation to site
of drug action
factors that determine drug flow - ANSWER: blood flow to tissues
ability to exit vascular system
ability to enter cell
Drug ability to exit vascular system - ANSWER: capillary bed- typical
blood brain barreier
placenta drug transfer
protein binding - albumin
drug ability to enter cell - ANSWER: binds with receptors on external surface of cell
membrane
drug metabolism - ANSWER: the enzymatic biotransformation of a drug structure
most occur in liver by P450 system
first pass effect - ANSWER: rapid hepatic inactivation of drug on its first pass through
liver
drug excretion - ANSWER: elimination of a drug from the body
Drug Excretion Routes - ANSWER: renal
breast milk
bile
lungs
sweat
saliva
therapeutic drug range - ANSWER: range of drug between minimum effective dose
and toxic dose. larger index - safer dose smaller index- harmful dose
drug half life - ANSWER: the time required for the amount of drug in the body to
decrease by 50%
Phamacodynamics - ANSWER: biochemical and physiological effects of drugs on body
dose-response relationship - ANSWER: the relationship between the size of an
administered dose and the intensity it produces
