Pathophysiology Exam 1
An ordered photographic show of a fixed of chromosomes from a unmarried mobile is a(n):
A) metaphase unfold.
B) autosomal unfold.
C) karyotype.
D) anaphase spread. - ANSc
An mistakes wherein homologous chromosomes fail to split in the course of meiosis is termed:
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
D) anaplasia. - ANSb
A somatic cellular that does not contain a multiple of 23 chromosomes is referred to as:
A) an aneuploid cell.
B) a euploid cellular.
C) a polyploidy cellular.
D) a haploid mobile. - ANSa
A 20-year-vintage pregnant woman gives beginning to a stillborn toddler. Autopsy famous that
the fetus has 92 chromosomes. Which of the subsequent describes this condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy - ANSc
If a person is a chromosomal mosaic, the man or woman may additionally:
A) be a service of the genetic disease.
B) have a slight form of the genetic disorder.
C) have two genetic diseases.
D) be sterile as a result of the genetic ailment. - ANSb
The most not unusual purpose of Down syndrome is:
A) paternal nondisjunction.
B) maternal translocations.
C) maternal nondisjunction.
D) paternal translocations. - ANSc
Risk factors for Down syndrome encompass:
A) fetal exposure to mutagens inside the uterus.
B) increased paternal age.
,C) circle of relatives history of Down syndrome.
D) pregnancy in girls over age 35. - ANSd
A thirteen-yr-old female has a karyotype that exhibits an absent homologous X chromosome
with best a single X chromosome gift. Her circumstance is called:
A) Down syndrome.
B) Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome - ANSc
A child is identified with cystic fibrosis. History reveals that the child's dad and mom are first
cousins. Cystic fibrosis turned into most probable the end result of:
A) X inactivation.
B) genomic imprinting.
C) consanguinity.
D) obligate companies. - ANSc
Joey, age nine, is admitted to a pediatric unit with Duchenne muscular dystrophy. He inherited
this circumstance through a:
A) sex-related dominant trait.
B) intercourse-encouraged trait.
C) intercourse-constrained trait.
D) sex-linked recessive trait. - ANSd
A 50-year-antique male changed into these days identified with Huntington sickness.
Transmission of this ailment is associated with:
A) penetrance.
B) recurrence chance.
C) expressivity.
D) delayed age of onset. - ANSd
People who have neurofibromatosis will show various levels of the ailment; this is because of
the genetic principle of:
A) penetrance.
B) expressivity.
C) dominance.
D) recessiveness. - ANSb
Cystic fibrosis is due to an _____ gene.
A) X-connected dominant
B) X-related recessive
C) autosomal dominant
D) autosomal recessive - ANSd
, To explicit a polygenic trait:
A) genes have to interact with the environment.
B) several genes have to act together.
C) more than one mutations need to arise inside the equal family.
D) in situ cloning must arise. - ANSb
The sluggish growth in height the various human population during the last one hundred years
is an example of:
A) polygenic trait.
B) multifactorial trait.
C) crossing over.
D) recombination. - ANSb
A couple has three offspring: one child with an autosomal dominant disease trait and who're
regular. The father is stricken by the autosomal dominant ailment, but the mom does no longer
have the sickness gene. What is the recurrence hazard of this autosomal dominant sickness for
their next baby?
A) 50%
B) 33%
C) 25%
D) Impossible to determine - ANSa
A 12-year-antique male is diagnosed with Klinefelter syndrome. His karyotype might reveal
which of the following?
A) XY
B) XX
C) XYY
D) XXY - ANSd
A 5-12 months-vintage male offers with mental retardation and is diagnosed with Fragile X
syndrome. Which of the subsequent is most in all likelihood to purpose this syndrome?
A) Translocation
B) Inversion
C) Nondisjunction
D) Duplication at fragile web sites - ANSd
The outward manifestation of a disease, regularly inspired with the aid of both genes and the
environment, is called the disorder:
A) genotype.
B) allele.
C) phenotype.
D) dominance. - ANSc
An ordered photographic show of a fixed of chromosomes from a unmarried mobile is a(n):
A) metaphase unfold.
B) autosomal unfold.
C) karyotype.
D) anaphase spread. - ANSc
An mistakes wherein homologous chromosomes fail to split in the course of meiosis is termed:
A) aneuploidy.
B) nondisjunction.
C) polyploidy.
D) anaplasia. - ANSb
A somatic cellular that does not contain a multiple of 23 chromosomes is referred to as:
A) an aneuploid cell.
B) a euploid cellular.
C) a polyploidy cellular.
D) a haploid mobile. - ANSa
A 20-year-vintage pregnant woman gives beginning to a stillborn toddler. Autopsy famous that
the fetus has 92 chromosomes. Which of the subsequent describes this condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy - ANSc
If a person is a chromosomal mosaic, the man or woman may additionally:
A) be a service of the genetic disease.
B) have a slight form of the genetic disorder.
C) have two genetic diseases.
D) be sterile as a result of the genetic ailment. - ANSb
The most not unusual purpose of Down syndrome is:
A) paternal nondisjunction.
B) maternal translocations.
C) maternal nondisjunction.
D) paternal translocations. - ANSc
Risk factors for Down syndrome encompass:
A) fetal exposure to mutagens inside the uterus.
B) increased paternal age.
,C) circle of relatives history of Down syndrome.
D) pregnancy in girls over age 35. - ANSd
A thirteen-yr-old female has a karyotype that exhibits an absent homologous X chromosome
with best a single X chromosome gift. Her circumstance is called:
A) Down syndrome.
B) Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome - ANSc
A child is identified with cystic fibrosis. History reveals that the child's dad and mom are first
cousins. Cystic fibrosis turned into most probable the end result of:
A) X inactivation.
B) genomic imprinting.
C) consanguinity.
D) obligate companies. - ANSc
Joey, age nine, is admitted to a pediatric unit with Duchenne muscular dystrophy. He inherited
this circumstance through a:
A) sex-related dominant trait.
B) intercourse-encouraged trait.
C) intercourse-constrained trait.
D) sex-linked recessive trait. - ANSd
A 50-year-antique male changed into these days identified with Huntington sickness.
Transmission of this ailment is associated with:
A) penetrance.
B) recurrence chance.
C) expressivity.
D) delayed age of onset. - ANSd
People who have neurofibromatosis will show various levels of the ailment; this is because of
the genetic principle of:
A) penetrance.
B) expressivity.
C) dominance.
D) recessiveness. - ANSb
Cystic fibrosis is due to an _____ gene.
A) X-connected dominant
B) X-related recessive
C) autosomal dominant
D) autosomal recessive - ANSd
, To explicit a polygenic trait:
A) genes have to interact with the environment.
B) several genes have to act together.
C) more than one mutations need to arise inside the equal family.
D) in situ cloning must arise. - ANSb
The sluggish growth in height the various human population during the last one hundred years
is an example of:
A) polygenic trait.
B) multifactorial trait.
C) crossing over.
D) recombination. - ANSb
A couple has three offspring: one child with an autosomal dominant disease trait and who're
regular. The father is stricken by the autosomal dominant ailment, but the mom does no longer
have the sickness gene. What is the recurrence hazard of this autosomal dominant sickness for
their next baby?
A) 50%
B) 33%
C) 25%
D) Impossible to determine - ANSa
A 12-year-antique male is diagnosed with Klinefelter syndrome. His karyotype might reveal
which of the following?
A) XY
B) XX
C) XYY
D) XXY - ANSd
A 5-12 months-vintage male offers with mental retardation and is diagnosed with Fragile X
syndrome. Which of the subsequent is most in all likelihood to purpose this syndrome?
A) Translocation
B) Inversion
C) Nondisjunction
D) Duplication at fragile web sites - ANSd
The outward manifestation of a disease, regularly inspired with the aid of both genes and the
environment, is called the disorder:
A) genotype.
B) allele.
C) phenotype.
D) dominance. - ANSc
